n(1)-methylnicotinamide has been researched along with Leukemia, Erythroblastic, Acute in 2 studies
N(1)-methylnicotinamide: RN given refers to parent cpd
1-methylnicotinamide : A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent.
Leukemia, Erythroblastic, Acute: A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Exposure of murine erythroleukemia cells (MELCs) to nicotinamide (NA) or its synthetic analog N'-methylnicotinamide (N'-MN) reduces cell growth and induces terminal differentiation, marked by increased heme and globin accumulation." | 1.34 | 1-Methylnicotinamide stimulates cell growth and inhibits hemoglobin synthesis in differentiating murine erythroleukemia cells. ( Cox, R; Kinder, D; Kuykendall, JR, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuykendall, JR | 2 |
| Cox, R | 2 |
| Kinder, D | 1 |
2 other studies available for n(1)-methylnicotinamide and Leukemia, Erythroblastic, Acute
| Article | Year |
|---|---|
1-Methylnicotinamide stimulates cell growth and inhibits hemoglobin synthesis in differentiating murine erythroleukemia cells.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Erythropoiesis; Globins; Hemogl | 2007 |
Detection of 5-methylcytosine removal from DNA of Friend erythroleukemia cells following exposure to several differentiating agents.
Topics: 5-Methylcytosine; Acetamides; Animals; Cell Differentiation; Cytosine; Dimethyl Sulfoxide; DNA; Frie | 1989 |