n(1)-methylnicotinamide has been researched along with Diabetes Mellitus, Type 2 in 5 studies
N(1)-methylnicotinamide: RN given refers to parent cpd
1-methylnicotinamide : A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with manifest type 2 diabetes have a significantly (approximately twofold) higher NNMT expression both in omental and subcutaneous WAT compared with controls." | 2.80 | Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance. ( Blüher, M; Dietrich, A; Kannt, A; Klöting, N; Pfenninger, A; Schön, MR; Teichert, L; Tönjes, A, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 2 |
| Chen, Y | 2 |
| Liu, C | 2 |
| Li, L | 3 |
| Li, P | 2 |
| Kannt, A | 1 |
| Pfenninger, A | 1 |
| Teichert, L | 1 |
| Tönjes, A | 1 |
| Dietrich, A | 1 |
| Schön, MR | 1 |
| Klöting, N | 1 |
| Blüher, M | 1 |
| Liu, M | 1 |
| Chu, J | 1 |
| Zhu, B | 1 |
| Zhang, Q | 1 |
| Yin, X | 1 |
| Jiang, W | 1 |
| Dai, G | 1 |
| Ju, W | 1 |
| Wang, Z | 1 |
| Yang, Q | 1 |
| Fang, Z | 1 |
| Zhou, SS | 1 |
| Li, D | 1 |
| Sun, WP | 1 |
| Guo, M | 1 |
| Lun, YZ | 1 |
| Zhou, YM | 1 |
| Xiao, FC | 1 |
| Jing, LX | 1 |
| Sun, SX | 1 |
| Zhang, LB | 1 |
| Luo, N | 1 |
| Bian, FN | 1 |
| Zou, W | 1 |
| Dong, LB | 1 |
| Zhao, ZG | 1 |
| Li, SF | 1 |
| Gong, XJ | 1 |
| Yu, ZG | 1 |
| Sun, CB | 1 |
| Zheng, CL | 1 |
| Jiang, DJ | 1 |
| Li, ZN | 1 |
1 trial available for n(1)-methylnicotinamide and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance.
Topics: Adult; Aged; Bariatric Surgery; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Diabetes | 2015 |
4 other studies available for n(1)-methylnicotinamide and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
N
Topics: Acetylation; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; Forkhead Box Protein O1; | 2020 |
N1‑methylnicotinamide ameliorates insulin resistance in skeletal muscle of type 2 diabetic mice by activating the SIRT1/PGC‑1α signaling pathway.
Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Insulin Receptor Sub | 2021 |
Serum N(1)-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese.
Topics: Adult; Asian People; Body Mass Index; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fem | 2015 |
Nicotinamide overload may play a role in the development of type 2 diabetes.
Topics: Adult; Aged; Aldehyde Oxidase; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Erythrocytes; Fema | 2009 |