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n(1)-methylnicotinamide and Alloxan Diabetes

n(1)-methylnicotinamide has been researched along with Alloxan Diabetes in 5 studies

N(1)-methylnicotinamide: RN given refers to parent cpd
1-methylnicotinamide : A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent.

Research Excerpts

ExcerptRelevanceReference
"Comparisons were made of the dose-response and time-course characteristics of nicotinamide (NIC) and its metabolite, N1-methylnicotinamide (MNIC), protection from alloxan-induced diabetes in mice."5.27Characteristics of nicotinamide and N1-methylnicotinamide protection from alloxan diabetes in mice. ( Falany, J; Fischer, LJ; Fisher, R, 1983)
"Comparisons were made of the dose-response and time-course characteristics of nicotinamide (NIC) and its metabolite, N1-methylnicotinamide (MNIC), protection from alloxan-induced diabetes in mice."1.27Characteristics of nicotinamide and N1-methylnicotinamide protection from alloxan diabetes in mice. ( Falany, J; Fischer, LJ; Fisher, R, 1983)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Chen, Y1
Zhang, J1
Li, P1
Liu, C1
Li, L1
Przyborowski, K1
Wojewoda, M1
Sitek, B1
Zakrzewska, A1
Kij, A1
Wandzel, K1
Zoladz, JA1
Chlopicki, S2
Kuchmerovska, T1
Shymanskyy, I1
Klimenko, A1
Országhová, Z1
Uličná, O1
Liptáková, A1
Zitňanová, I1
Muchová, J1
Watala, C1
Duračková, Z1
Fischer, LJ1
Falany, J1
Fisher, R1

Other Studies

5 other studies available for n(1)-methylnicotinamide and Alloxan Diabetes

ArticleYear
N1‑methylnicotinamide ameliorates insulin resistance in skeletal muscle of type 2 diabetic mice by activating the SIRT1/PGC‑1α signaling pathway.
    Molecular medicine reports, 2021, Volume: 23, Issue:4

    Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Insulin Receptor Sub

2021
Effects of 1-Methylnicotinamide (MNA) on Exercise Capacity and Endothelial Response in Diabetic Mice.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Epoprostenol;

2015
1-methylnicotinamide (MNA) in prevention of diabetes-associated brain disorders.
    Neurochemistry international, 2010, Volume: 56, Issue:2

    Topics: Animals; Brain Diseases; Diabetes Mellitus, Experimental; Male; Niacinamide; Rats; Serotonin; Signal

2010
Effects of N1-methylnicotinamide on oxidative and glycooxidative stress markers in rats with streptozotocin-induced diabetes mellitus.
    Redox report : communications in free radical research, 2012, Volume: 17, Issue:1

    Topics: Animals; Antioxidants; Biomarkers; Diabetes Mellitus, Experimental; DNA Damage; Drug Evaluation, Pre

2012
Characteristics of nicotinamide and N1-methylnicotinamide protection from alloxan diabetes in mice.
    Toxicology and applied pharmacology, 1983, Volume: 70, Issue:1

    Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug;

1983