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n(1)-acetylspermidine and Cancer of Colon

n(1)-acetylspermidine has been researched along with Cancer of Colon in 5 studies

N(1)-acetylspermidine : An acetylspermidine having the acetyl group at the N1-position.

Research Excerpts

ExcerptRelevanceReference
"The association of N1-acetylspermidine with human colorectal adenocarcinomas has been evaluated in this study."7.67Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas. ( Hoshi, H; Kimura, H; Matsuzaki, S; Nakamura, T; Nakano, G; Shoda, H; Takenoshita, S, 1984)
"The association of N1-acetylspermidine with human colorectal adenocarcinomas has been evaluated in this study."3.67Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas. ( Hoshi, H; Kimura, H; Matsuzaki, S; Nakamura, T; Nakano, G; Shoda, H; Takenoshita, S, 1984)
"When human colon cancer cells were exposed to 7beta-OHsitosterol and to 7beta-OHcholesterol at concentrations inhibiting growth by the same degree, both compounds caused a reduction of polyamine biosynthetic enzyme activity, of the polyamine pools, and an increase of N1-acetylspermidine concentration indicating the enhancement of polyamine catabolism."1.33Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol. ( Aoudé-Werner, D; Geoffroy, P; Gossé, F; Marchioni, E; Miesch, M; Raul, F; Roussi, S; Zhang, X, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roussi, S1
Gossé, F1
Aoudé-Werner, D1
Zhang, X1
Geoffroy, P1
Miesch, M1
Marchioni, E1
Raul, F1
Takenoshita, S1
Matsuzaki, S1
Nakano, G1
Kimura, H1
Hoshi, H1
Shoda, H1
Nakamura, T1
Halline, AG3
Dudeja, PK3
Brasitus, TA3
Lashner, BA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Urinary Excretion of Acetylamantadine by Cancer Patients[NCT02277938]120 participants (Anticipated)Observational2013-08-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for n(1)-acetylspermidine and Cancer of Colon

ArticleYear
Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol.
    International journal of oncology, 2006, Volume: 29, Issue:6

    Topics: Biogenic Polyamines; Caco-2 Cells; Cell Death; Cell Growth Processes; Colonic Neoplasms; Drug Synerg

2006
Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas.
    Cancer research, 1984, Volume: 44, Issue:2

    Topics: Adenocarcinoma; Adenoma; Chromatography, High Pressure Liquid; Colonic Neoplasms; Humans; Rectal Neo

1984
1,2-Dimethylhydrazine-induced alterations in N1-acetylspermidine levels in rat distal colonic mucosa: effects of 2-difluoromethylornithine.
    Biochimica et biophysica acta, 1989, Jul-21, Volume: 992, Issue:1

    Topics: 1,2-Dimethylhydrazine; Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Chromatography

1989
Urinary excretion of N1-acetylspermidine and other acetylated and free polyamines in the 1,2-dimethylhydrazine model of experimental rat colon cancer.
    Cancer research, 1989, Sep-01, Volume: 49, Issue:17

    Topics: 1,2-Dimethylhydrazine; Acetylation; Animals; Biogenic Polyamines; Biomarkers, Tumor; Colonic Neoplas

1989
Premalignant alterations in rat colonic N1-acetylspermidine levels induced by 1,2-dimethylhydrazine: effects of a high corn oil dietary regimen.
    Biochimica et biophysica acta, 1989, Mar-24, Volume: 990, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Biogenic Polyamines; Colonic Neoplasms; Corn Oil; Di

1989