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n(1), n(12)-diethylspermine and Leukemia L 1210

n(1), n(12)-diethylspermine has been researched along with Leukemia L 1210 in 10 studies

N(1), N(12)-diethylspermine: structure in first source
N(1),N(12)-diethylspermine : A substituted spermine that is spermine in which a hydrogen attached to each of the primary amino groups has been replaced by an ethyl group.

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's7 (70.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergeron, RJ9
Neims, AH1
McManis, JS3
Hawthorne, TR2
Vinson, JR3
Bortell, R1
Ingeno, MJ2
Liu, CZ1
Feng, Y3
Weimar, WR3
Luchetta, GR1
Wu, Q2
Ortiz-Ocasio, J1
Kramer, D1
Yao, GW1
Yao, H1
Sninsky, CA1
Raisler, B2
Gao, F1
Dimova, H1
Porter, C1
Phanstiel, O1
Albanese, L1
Pegg, AE3
Poulin, R1
Vertino, PM1
Beerman, TA1
Kelly, EJ1
Porter, CW3
Ganis, B1
Madhabala, R1
Beck, DE1
McManis, J1
Casero, RA1

Other Studies

10 other studies available for n(1), n(12)-diethylspermine and Leukemia L 1210

ArticleYear
Synthetic polyamine analogues as antineoplastics.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:6

    Topics: Animals; Antineoplastic Agents; DNA, Mitochondrial; Leukemia L1210; Male; Mice; Mice, Inbred DBA; Po

1988
Antiproliferative properties of polyamine analogues: a structure-activity study.
    Journal of medicinal chemistry, 1994, Oct-14, Volume: 37, Issue:21

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Cell Division;

1994
Metabolically programmed polyamine analogue antidiarrheals.
    Journal of medicinal chemistry, 1996, Jun-21, Volume: 39, Issue:13

    Topics: Animals; Antidiarrheals; Biological Transport; Castor Oil; Cell Division; Computer Simulation; Diarr

1996
A comparison of structure-activity relationships between spermidine and spermine analogue antineoplastics.
    Journal of medicinal chemistry, 1997, May-09, Volume: 40, Issue:10

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cell Division;

1997
Investigations of the mechanism by which mammalian cell growth is inhibited by N1N12-bis(ethyl)spermine.
    The Biochemical journal, 1993, Apr-01, Volume: 291 ( Pt 1)

    Topics: Animals; Cell Division; Cell Line; DNA, Mitochondrial; Humans; Leukemia L1210; Mitoguazone; Oxygen C

1993
Stable intracellular acidification upon polyamine depletion induced by alpha-difluoromethylornithine or N1,N12-bis(ethyl)spermine in L1210 leukaemia cells.
    The Biochemical journal, 1995, Dec-15, Volume: 312 ( Pt 3)

    Topics: Animals; Antineoplastic Agents; Bicarbonates; Eflornithine; Hydrogen-Ion Concentration; Leukemia L12

1995
Selective cellular depletion of mitochondrial DNA by the polyamine analog N1,N12-bis(ethyl)spermine and its relationship to polyamine structure and function.
    Molecular pharmacology, 1991, Volume: 39, Issue:4

    Topics: Animals; Antineoplastic Agents; Blotting, Southern; Cell Division; Cell Line, Transformed; DNA; DNA

1991
Combined regulation of ornithine and S-adenosylmethionine decarboxylases by spermine and the spermine analogue N1 N12-bis(ethyl)spermine.
    The Biochemical journal, 1990, May-15, Volume: 268, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Kinetics; Leukemia

1990
Role of the methylene backbone in the antiproliferative activity of polyamine analogues on L1210 cells.
    Cancer research, 1989, Jun-01, Volume: 49, Issue:11

    Topics: Animals; Antineoplastic Agents; Binding, Competitive; Cell Division; Cell Survival; DNA, Neoplasm; L

1989
Relative abilities of bis(ethyl) derivatives of putrescine, spermidine, and spermine to regulate polyamine biosynthesis and inhibit L1210 leukemia cell growth.
    Cancer research, 1987, Jun-01, Volume: 47, Issue:11

    Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Cell Division; Leukemia L1210; Mice

1987