n(1), n(12)-diethylspermine has been researched along with Carcinoma, Anaplastic in 3 studies
N(1), N(12)-diethylspermine: structure in first source
N(1),N(12)-diethylspermine : A substituted spermine that is spermine in which a hydrogen attached to each of the primary amino groups has been replaced by an ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cytotoxic response of the human large cell lung carcinoma line NCI H157 to exposure to the polyamine analogue N1 N12-bis(ethyl)spermine (BESpm) is preceded by an extremely high induction of spermidine/spermine N1-acetyltransferase (SSAT)." | 7.68 | High specific induction of spermidine/spermine N1-acetyltransferase in a human large cell lung carcinoma. ( Casero, RA; Celano, P; Ervin, SJ; Pegg, AE; Wiest, L, 1990) |
| " Detailed studies with estrogen receptor-positive MCF-7 and estrogen receptor- negative Hs578t cells show a similar dose-response curve with concentrations of 1-10 microM resulting in maximal growth inhibition." | 5.29 | Growth inhibition of hormone-responsive and -resistant human breast cancer cells in culture by N1, N12-bis(ethyl)spermine. ( Bergeron, RJ; Casero, RA; Davidson, NE; Mank, AR; Prestigiacomo, LJ, 1993) |
| "The cytotoxic response of the human large cell lung carcinoma line NCI H157 to exposure to the polyamine analogue N1 N12-bis(ethyl)spermine (BESpm) is preceded by an extremely high induction of spermidine/spermine N1-acetyltransferase (SSAT)." | 3.68 | High specific induction of spermidine/spermine N1-acetyltransferase in a human large cell lung carcinoma. ( Casero, RA; Celano, P; Ervin, SJ; Pegg, AE; Wiest, L, 1990) |
| " Detailed studies with estrogen receptor-positive MCF-7 and estrogen receptor- negative Hs578t cells show a similar dose-response curve with concentrations of 1-10 microM resulting in maximal growth inhibition." | 1.29 | Growth inhibition of hormone-responsive and -resistant human breast cancer cells in culture by N1, N12-bis(ethyl)spermine. ( Bergeron, RJ; Casero, RA; Davidson, NE; Mank, AR; Prestigiacomo, LJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davidson, NE | 1 |
| Mank, AR | 1 |
| Prestigiacomo, LJ | 1 |
| Bergeron, RJ | 2 |
| Casero, RA | 3 |
| Celano, P | 2 |
| Ervin, SJ | 2 |
| Wiest, L | 1 |
| Pegg, AE | 1 |
| Baylin, SB | 1 |
3 other studies available for n(1), n(12)-diethylspermine and Carcinoma, Anaplastic
| Article | Year |
|---|---|
Growth inhibition of hormone-responsive and -resistant human breast cancer cells in culture by N1, N12-bis(ethyl)spermine.
Topics: Acetyltransferases; Breast Neoplasms; Carcinoma; Cell Division; Drug Resistance; Enzyme Induction; F | 1993 |
High specific induction of spermidine/spermine N1-acetyltransferase in a human large cell lung carcinoma.
Topics: Acetyltransferases; Amino Acid Sequence; Amino Acids; Blotting, Western; Carcinoma; Enzyme Induction | 1990 |
Differential response to treatment with the bis(ethyl)polyamine analogues between human small cell lung carcinoma and undifferentiated large cell lung carcinoma in culture.
Topics: Adenosylmethionine Decarboxylase; Carcinoma; Carcinoma, Small Cell; Cells, Cultured; Humans; Lung Ne | 1989 |