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n(1), n(12)-diethylspermine and Carcinoma, Anaplastic

n(1), n(12)-diethylspermine has been researched along with Carcinoma, Anaplastic in 3 studies

N(1), N(12)-diethylspermine: structure in first source
N(1),N(12)-diethylspermine : A substituted spermine that is spermine in which a hydrogen attached to each of the primary amino groups has been replaced by an ethyl group.

Research Excerpts

ExcerptRelevanceReference
"The cytotoxic response of the human large cell lung carcinoma line NCI H157 to exposure to the polyamine analogue N1 N12-bis(ethyl)spermine (BESpm) is preceded by an extremely high induction of spermidine/spermine N1-acetyltransferase (SSAT)."7.68High specific induction of spermidine/spermine N1-acetyltransferase in a human large cell lung carcinoma. ( Casero, RA; Celano, P; Ervin, SJ; Pegg, AE; Wiest, L, 1990)
" Detailed studies with estrogen receptor-positive MCF-7 and estrogen receptor- negative Hs578t cells show a similar dose-response curve with concentrations of 1-10 microM resulting in maximal growth inhibition."5.29Growth inhibition of hormone-responsive and -resistant human breast cancer cells in culture by N1, N12-bis(ethyl)spermine. ( Bergeron, RJ; Casero, RA; Davidson, NE; Mank, AR; Prestigiacomo, LJ, 1993)
"The cytotoxic response of the human large cell lung carcinoma line NCI H157 to exposure to the polyamine analogue N1 N12-bis(ethyl)spermine (BESpm) is preceded by an extremely high induction of spermidine/spermine N1-acetyltransferase (SSAT)."3.68High specific induction of spermidine/spermine N1-acetyltransferase in a human large cell lung carcinoma. ( Casero, RA; Celano, P; Ervin, SJ; Pegg, AE; Wiest, L, 1990)
" Detailed studies with estrogen receptor-positive MCF-7 and estrogen receptor- negative Hs578t cells show a similar dose-response curve with concentrations of 1-10 microM resulting in maximal growth inhibition."1.29Growth inhibition of hormone-responsive and -resistant human breast cancer cells in culture by N1, N12-bis(ethyl)spermine. ( Bergeron, RJ; Casero, RA; Davidson, NE; Mank, AR; Prestigiacomo, LJ, 1993)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davidson, NE1
Mank, AR1
Prestigiacomo, LJ1
Bergeron, RJ2
Casero, RA3
Celano, P2
Ervin, SJ2
Wiest, L1
Pegg, AE1
Baylin, SB1

Other Studies

3 other studies available for n(1), n(12)-diethylspermine and Carcinoma, Anaplastic

ArticleYear
Growth inhibition of hormone-responsive and -resistant human breast cancer cells in culture by N1, N12-bis(ethyl)spermine.
    Cancer research, 1993, May-01, Volume: 53, Issue:9

    Topics: Acetyltransferases; Breast Neoplasms; Carcinoma; Cell Division; Drug Resistance; Enzyme Induction; F

1993
High specific induction of spermidine/spermine N1-acetyltransferase in a human large cell lung carcinoma.
    The Biochemical journal, 1990, Sep-15, Volume: 270, Issue:3

    Topics: Acetyltransferases; Amino Acid Sequence; Amino Acids; Blotting, Western; Carcinoma; Enzyme Induction

1990
Differential response to treatment with the bis(ethyl)polyamine analogues between human small cell lung carcinoma and undifferentiated large cell lung carcinoma in culture.
    Cancer research, 1989, Feb-01, Volume: 49, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Carcinoma; Carcinoma, Small Cell; Cells, Cultured; Humans; Lung Ne

1989