myelin-basic-protein and Affective-Disorders--Psychotic

myelin-basic-protein has been researched along with Affective-Disorders--Psychotic* in 1 studies

Other Studies

1 other study(ies) available for myelin-basic-protein and Affective-Disorders--Psychotic

ArticleYear
[The state of the immune system in endogenous mental diseases with pronounced affective disorders].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2011, Volume: 111, Issue:12

    Parameters of innate and adaptive immunity were studied in the blood serum of 180 patients, aged 15-25 years, with different endogenous mental diseases with depressive and mania disorders in the clinical picture (affective psychoses (29 patients), schizoaffective psychoses (106 patients) , slow-progressive schizophrenia (23 patients) and intermittent-progressive schizophrenia (22 patients)). The activation of innate immunity (the increase in the degranulation activity of leukocyte elastase (LE) and functional activity of alpha-1-proteinase inhibitor (α1-PI) were found in all the diseases. The increase in disease severity (from affective disorders to intermittent-progressive schizophrenia) was correlated with the significant elevation of LE activity. The LE activity did not depend on the polarity and severity of affective pathology in each diagnostic group. The mean levels of autoantibodies to the nerve growth factor and the myelin basic protein did not differ from the control values in all the groups of patients.

    Topics: Adaptive Immunity; Adolescent; Adult; Affective Disorders, Psychotic; alpha 1-Antitrypsin; Autoantibodies; Female; Humans; Immune System; Immunity, Innate; Leukocyte Elastase; Male; Myelin Basic Protein; Nerve Growth Factor; Schizophrenia; Young Adult

2011