mycophenolic-acid and Thrombocythemia--Essential

mycophenolic-acid has been researched along with Thrombocythemia--Essential* in 1 studies

Other Studies

1 other study(ies) available for mycophenolic-acid and Thrombocythemia--Essential

Article	Year
Henoch-Schonlein Purpura with thrombocythaemia: an abnormality in Smad4 expression? Rheumatology international, 2009, Volume: 29, Issue:5 We discuss a patient with Henoch-Schonlein Purpura (HSP) and a thrombocythaemia which was diagnosed as a coincidental Essential Thrombocythaemia. We suggest that deficiencies in Smad4 expression may allow for escape thrombocythaemia under the influence of the high levels of TGF-beta found in HSP. With normal Smad4 expression TGF-beta provides inhibition of thrombocyte proliferation. While this needs further elucidation, it could lead to a new approach to classification and management of HSP. Topics: Biopsy; Blood Platelets; Cell Proliferation; Dermatologic Surgical Procedures; Female; Follow-Up Studies; Humans; IgA Vasculitis; Immunosuppressive Agents; Middle Aged; Mycophenolic Acid; Platelet Count; Prednisolone; Skin; Smad4 Protein; Thrombocythemia, Essential; Time Factors; Transforming Growth Factor beta; Treatment Outcome	2009

Article

Year

Henoch-Schonlein Purpura with thrombocythaemia: an abnormality in Smad4 expression?

Rheumatology international, 2009, Volume: 29, Issue:5

We discuss a patient with Henoch-Schonlein Purpura (HSP) and a thrombocythaemia which was diagnosed as a coincidental Essential Thrombocythaemia. We suggest that deficiencies in Smad4 expression may allow for escape thrombocythaemia under the influence of the high levels of TGF-beta found in HSP. With normal Smad4 expression TGF-beta provides inhibition of thrombocyte proliferation. While this needs further elucidation, it could lead to a new approach to classification and management of HSP.

Topics: Biopsy; Blood Platelets; Cell Proliferation; Dermatologic Surgical Procedures; Female; Follow-Up Studies; Humans; IgA Vasculitis; Immunosuppressive Agents; Middle Aged; Mycophenolic Acid; Platelet Count; Prednisolone; Skin; Smad4 Protein; Thrombocythemia, Essential; Time Factors; Transforming Growth Factor beta; Treatment Outcome

2009