mycophenolic-acid and Lymphoma--T-Cell

Subcutaneous panniculitis-like T-cell lymphoma is a rare, indolent cutaneous cytotoxic alpha-beta T-cell lymphoma, where no specific therapy regimen is defined. We present a case with a diagnostically challenging association with anti-double stranded DNA and provides one of the first reports of a successful treatment with mycophenolate mofetil and glucocorticosteroids.

Topics: Humans; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Mycophenolic Acid; Panniculitis; Skin Neoplasms

Topics: Antibiotics, Antineoplastic; Female; Humans; Lymphoma, T-Cell; Middle Aged; Mycophenolic Acid; Panniculitis; Prognosis; Receptors, Antigen, T-Cell, gamma-delta

Posttransplant lymphoproliferative disorders (PTLD) are a potentially life-threatening complication of immunosuppression in transplant recipients. The majority of cases are Epstein-Barr virus-associated lesions of B cell origin. T cell PTLD is rare, particularly in pediatric patients. We present an unusual case of monomorphic T cell PTLD with features of angioimmunoblastic T cell lymphoma in an 8-year-old heart transplant patient, presenting with cranial nerve palsy.

Topics: Alveolitis, Extrinsic Allergic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Cyclophosphamide; Cytarabine; Etoposide; Heart Transplantation; Humans; Hydrocortisone; Immunoblastic Lymphadenopathy; Immunocompromised Host; Immunophenotyping; Immunosuppressive Agents; Kartagener Syndrome; Lymphoma, T-Cell; Methotrexate; Mycophenolic Acid; Oculomotor Nerve Diseases; Postoperative Complications; Prednisone; Remission Induction; T-Lymphocyte Subsets; Tacrolimus; Vincristine