mycophenolic-acid and Ileitis

We report a case of mycophenolate mofetil-induced collagenous ileitis in a kidney transplant patient. A 38-year-old Chinese man who had received a kidney transplant 3 years earlier was admitted to our department for severe diarrhea and rapid weight loss. Infection studies were negative, and tumors were ruled out, so drug-induced factors were suspected. He had been taking mycophenolate mofetil for immunosuppression, which was then suspended, and he had a rapid resolution of diarrhea. Pathological findings of gastrointestinal endoscopy biopsy showed the presence of thickened collagen bands in the subepithelium of the terminal ileum. This is the first report of collagenous ileitis caused by mycophenolate mofetil in a patient with a kidney transplantation, adding another reversible cause to this rare condition. It is important for clinicians to recognize and treat it promptly.

Topics: Adult; Diarrhea; Graft Rejection; Humans; Ileitis; Immunosuppressive Agents; Kidney Transplantation; Male; Mycophenolic Acid

Topics: Anemia, Iron-Deficiency; Diabetic Nephropathies; Humans; Ileitis; Ileum; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Single-Balloon Enteroscopy; Ulcer

Topics: Colitis; Colonoscopy; Histoplasmosis; Humans; Ileitis; Immunocompromised Host; Immunosuppressive Agents; Lung Diseases, Interstitial; Male; Middle Aged; Mycophenolic Acid; Prednisone; Scleroderma, Systemic

Topics: Abdominal Pain; Crohn Disease; Humans; Ileitis; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid