mycophenolic-acid and Hypertension--Malignant

mycophenolic-acid has been researched along with Hypertension--Malignant* in 1 studies

Other Studies

1 other study(ies) available for mycophenolic-acid and Hypertension--Malignant

ArticleYear
Renal manifestations in toddlers with Takayasu's arteritis and malignant hypertension.
    Pediatric nephrology (Berlin, Germany), 2009, Volume: 24, Issue:6

    Three children under the age of 3 years presented with malignant hypertension, proteinuria, and acute kidney injury. Takayasu's arteritis was diagnosed on the basis of clinical symptoms of weight loss and low grade fever in conjunction with elevated sedimentation rate and radiographic evidence of aortic and renal artery stenosis. One patient had a renal biopsy which showed arteriolar sclerosis and focal glomerulosclerosis. All three patients required multiple antihypertensive agents, ultimately including angiotensin receptor blockers and/or angiotensin converting enzyme inhibitors. The vasculitis was treated with pulse corticosteroids followed by cyclophosphamide in one patient and mycophenolate mofetil as maintenance therapy in all. Follow-up has ranged from 2 to 8 years. Although global renal function has normalized in each patient, two have unilateral non-function of one kidney. The last patient has persistent aortic and renal artery stenosis with complex collateralization requiring ongoing medical and anticipated surgical management.

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biopsy; Child, Preschool; Female; Follow-Up Studies; Glomerulosclerosis, Focal Segmental; Humans; Hypertension, Malignant; Immunosuppressive Agents; Infant; Kidney; Male; Mycophenolic Acid; Renal Artery Obstruction; Takayasu Arteritis; Time Factors; Treatment Outcome

2009