mycophenolic-acid and Encephalitis

mycophenolic-acid has been researched along with Encephalitis* in 2 studies

Other Studies

2 other study(ies) available for mycophenolic-acid and Encephalitis

ArticleYear
Relapsing CD8+ encephalitis-looking for a solution.
    BMJ case reports, 2016, Jun-22, Volume: 2016

    CD8+ encephalitis (CD8+E) is an emerging and incompletely understood HIV-associated neurological syndrome, typically presenting as a steroid-responsive subacute encephalopathy with prominent white matter changes in patients with apparently well-controlled HIV infection. Some cases can be associated with the phenomenon of 'viral escape' (disproportionate replication within the cerebrospinal fluid), but the most important pathophysiology of CD8+E is thought to involve an attack on HIV-infected CD4+ lymphocytes by autoreactive CD8+ cells. We report a case of CD8+E where the initial positive response to steroid treatment was followed by several relapses on withdrawal. This led to the use of mycophenolate mofetil (MMF) as a long-term steroid-sparing agent, which is the first time this approach has been reported in the literature. The patient has now been on treatment with MMF for 10 months and it has been possible to taper the steroids down to a minimal maintenance dose without further relapse.

    Topics: Adult; CD8-Positive T-Lymphocytes; Drug Resistance; Drug Therapy, Combination; Encephalitis; Female; HIV Infections; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Mycophenolic Acid; Prednisolone; Recurrence; Remission Induction; Treatment Outcome; Viral Load

2016
Successful treatment of antiN-methyl-d-aspartate receptor limbic encephalitis in a 22-monthold child with plasmapheresis and pharmacological immunomodulation.
    Archives of disease in childhood, 2010, Volume: 95, Issue:4

    Topics: Autoantibodies; Autoimmune Diseases; Child; Combined Modality Therapy; Encephalitis; Female; Humans; Immunosuppressive Agents; Mycophenolic Acid; Plasmapheresis; Receptors, N-Methyl-D-Aspartate

2010