mycophenolic-acid and Diabetic-Angiopathies

We report a successful en bloc pancreas and kidney transplantation on a type I diabetic patient with advanced peripheral arterial calcific disease, who had frequent life-threatening episodes of hypoglycemia. The en bloc double organ, created by joining the graft renal artery to the arterial Y graft of the pancreas, was implanted to the proximal left common iliac artery, which was the only site available for an arterial anastomosis. Under appropriate circumstances, this procedure would be an option for potential combined pancreas-kidney transplant recipients with severe calcific arterial disease.

Topics: Adult; Anastomosis, Surgical; Arteriovenous Anastomosis; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Female; Graft Rejection; Humans; Iliac Artery; Iliac Vein; Immunosuppressive Agents; Kidney Transplantation; Methylprednisolone; Mycophenolic Acid; Pancreas Transplantation; Postoperative Period; Radionuclide Imaging; Regional Blood Flow; Tacrolimus; Technetium Tc 99m Pentetate