mycophenolic-acid and Angioedemas--Hereditary

Here, we report a family with two children (the elder son and younger daughter) diagnosed with juvenile-onset systemic lupus erythematosus (SLE) and the father diagnosed with hereditary angioedema. Serum C1 inhibitor (C1-INH) levels were low, and clinical exome next-generation sequencing detected a frameshift mutation in the

Topics: Angioedemas, Hereditary; Complement C1 Inhibitor Protein; Family; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Male; Middle Aged; Mycophenolic Acid; Phenotype; Steroids; Young Adult