Page last updated: 2024-08-21

mustard gas and Innate Inflammatory Response

mustard gas has been researched along with Innate Inflammatory Response in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-19904 (6.56)18.7374
1990's4 (6.56)18.2507
2000's17 (27.87)29.6817
2010's30 (49.18)24.3611
2020's6 (9.84)2.80

Authors

AuthorsStudies
Cohen, M; Dachir, S; Egoz, I; Gez, R; Gutman, H; Horwitz, V; Kadar, T1
Cen, J; Gong, C; Han, H; He, X; Hu, B; Mao, G; Meng, W; Pei, Z; Sun, M; Wan, J; Xiao, K; Xu, Q; Zhang, X1
Bhaskar, ASB; Gupta, AK; Kannan, GM; Nagar, DP; Pathak, U; Soni, AK1
Pal, A; Pal, S; Rizwan, H; Sabnam, S1
Ahmad, A; Ahmad, S; Chandrashekar, DS; Hamid, T; Husain, M; Mariappan, N; Rana, T; Varambally, S; Zafar, I1
Abramova, EV; Casillas, RP; Croutch, CR; Laskin, DL; Laskin, JD; Malaviya, R; Napierala, M; Peters, E; Rancourt, RC; Roseman, J; Sunil, VR; Tuttle, R; Weinstock, D1
Bei, YY; Han, W; Li, Y; Liu, F; Yu, D; Zhao, J; Zhao, YL; Zhong, YX; Zhu, XJ1
Ghanei, M; Hassani, S; Panahi, Y; Sahebkar, A1
Jiang, N; Liu, F; Mei, Y; Wang, T; Zhang, X; Zhang, Y; Zhou, W1
Azimzadeh Jamalkandi, S; Iman, M; Kheradmand, F; Rezaei, R; Salimian, J; Shariati, P1
Ghanei, M; Hashjin, MM; Panahi, Y; Rezaee, R; Sahebkar, A1
Casillas, RP; Chang, YC; Gerecke, DR; Gordon, MK; Hahn, RA; Laskin, JD; Soriano, M1
Pal, A; Sabnam, S1
Borna, H; Ghanei, M; Ghatrehsamani, M; Harchegani, AB; Hosseini Qale Noe, SH; Shahriary, A; Talatappe, NR1
Kehe, K; Lang, S; Popp, T; Schmidt, A; Steinritz, D; Thiermann, H; Wagner, S1
Balszuweit, F; Bloemeke, B; Menacher, G; Schmidt, A; Steinritz, D; Thiermann, H; Worek, F1
Bashiri, S; Ghanei, M; Hajihashemi, A; Panahi, Y; Sahebkar, A1
Ahmad, A; Ahmad, S1
Azimzadeh Jamalkandi, S; Imani Fooladi, AA; Mahmoodzadeh Hosseini, H; Nourani, MR1
Pal, A; Pal, S; Parida, SR; Rizwan, H; Sabnam, S; Sagar, S; Swain, MM1
Ben-Sasson, S; Ben-Yehuda Greenwald, M; Bianco-Peled, H; Frušić-Zlotkin, M; Kohen, R; Soroka, Y1
Agarwal, R; Gu, M; Orlicky, DJ; Pal, A; Rana, S; Tewari-Singh, N; White, CW1
Casillas, RP; Gerecke, DR; Gordon, MK; Gray, JP; Heck, DE; Heindel, ND; Laskin, DL; Laskin, JD; Shakarjian, MP; Sinko, PJ1
Benson, J; Grotendorst, G; Jaramillo, R; March, T; Mishra, NC; Rir-sima-ah, J; Schultz, G; Seagrave, JC; Sopori, M; Weber, W1
Gao, X; Ishida, K; Ray, P; Ray, R; Xiao, Y1
Day, BJ; Hendry-Hofer, TB; Huang, J; Loader, JE; Min, E; O'Neill, HC; Rancourt, RC; Veress, LA; White, CW1
Black, AT; Casillas, RP; Gerecke, DR; Heck, DE; Joseph, LB; Laskin, DL; Laskin, JD; Sinko, PJ1
Ebrahimi, M; Imani Fooladi, AA; Keshavarz, S; Khaheshi, I; Nourani, MR; Panahi, Y; Shohrati, M; Yazdani, S1
Brannon, M; Kumari, S; Paromov, V; Qui, M; Samala, M; Smith, M; Stone, WL1
Fabio, KM; Flowers, RA; Guillon, CD; Harman, MP; Heck, DE; Heindel, ND; Huang, MT; Laskin, JD; Saxena, J; Vetrano, AM; Young, SC1
Ghanei, M; Harandi, AA1
Babin, MC; Black, AT; Casillas, RP; Cervelli, JA; Gerecke, DR; Heck, DE; Joseph, LB; Laskin, DL; Laskin, JD; Sinko, PJ1
Ebrahimi, M; Ghanei, M; Imani Fooladi, AA; Karimfar, MH; Mirbagheri, L; Nourani, MR; Yazdani, S1
Sahebkar, A1
Gow, AJ; Laskin, DL; Laskin, JD; Patel-Vayas, K; Shen, J; Sunil, VR1
Pohanka, M1
Agarwal, C; Agarwal, R; Inturi, S; Jain, AK; Tewari-Singh, N; White, CW1
Calvet, JH; d'Ortho, MP; Delamanche, S; Galiacy, S; Guignabert, C; Planus, E; Taysse, L1
Bellier, B; Breton, P; Daulon, S; Delamanche, S; Taysse, L1
Barker, PE; Gao, X; Ray, P; Ray, R; Xiao, Y1
Brodsky, B; Erlanger-Rosengarten, A; Proscura, E; Shapira, E; Wormser, U1
Abe, Y; Boulay, M; Dannenberg, AM; Dinh, TT; Lee, K; Rao, JB; Schofield, BH; Steinbeck, MJ; Tsuruta, J1
Abe, Y; Dannenberg, AM; Sugisaki, K1
Dube, SN; Husain, K; Somani, SM; Sugendran, K; Vijayaraghavan, R1
Blaha, M; Bowers, W; DuBose, D; Kohl, J; Walker, J1
Alkhyyat, A; Blaha, M; Bowers, W; DuBose, D; Kohl, J; Walker, J; Wong, G1
Amir, A; Chapman, S; Fishbeine, E; Frishman, G; Gilat, E; Kadar, T; Liani, H; Meshulam, J; Sahar, R; Turetz, J1
Atkins, KB; Hinshaw, DB; Hurley, LL; Lodhi, IJ1
Blank, JA; Casillas, RP; Lane, LA; Menton, RG1
Babin, MC; Casillas, RP; Gazaway, M; Mitcheltree, LW; Ricketts, K; Skvorak, JP1
Brozetti, JJ; Dick, EJ; Finger, AV; Hamilton, TA; Petrali, JP1
Allon, N; Amir, A; Chapman, S; Gozes, Y; Kadar, T; Sahar, R1
Arroyo, CM; Broomfield, CA; Carmichael, AJ; Kurt, EM; Schafer, RJ1
Casillas, RP; Doyel, TD; France, JA; Gazaway, MY; Graziosi, AM; Ricketts, KM; Santai, CT1
Broomfield, CA; Cowan, FM; Smith, WJ1
Meier, HL; Millard, C; Moser, J1
Beck, G; Boulay, MG; Habicht, GS; Hirshman, CA; Nakamura, M; Rennie, LL; Rikimaru, T; Spannhake, EW; Widra, M; Yano, T1
Dannenberg, AM; Harada, S; Higuchi, K; Kajiki, A; Nakamura, M; Pula, PJ; Scott, AL1
Dannenberg, AM; Harada, S; Higuchi, K; Kajiki, A; Liu, LH; Pula, PJ; Tanaka, F; Vogt, RF1
Dannenberg, AM; Harada, S; Higuchi, K; Kajiki, A; Pula, PJ; Tanaka, F1
Mráz, J; Simsa, J1

Reviews

10 review(s) available for mustard gas and Innate Inflammatory Response

ArticleYear
TGF-β and Th17 cells related injuries in patients with sulfur mustard exposure.
    Journal of cellular physiology, 2018, Volume: 233, Issue:4

    Topics: Humans; Inflammation; Lung; Mustard Gas; T-Lymphocytes, Regulatory; Th17 Cells; Transforming Growth Factor beta

2018
Th17/Treg immunoregulation and implications in treatment of sulfur mustard gas-induced lung diseases.
    Expert review of clinical immunology, 2017, Volume: 13, Issue:12

    Topics: Airway Obstruction; Airway Remodeling; Animals; Chemical Warfare; Goblet Cells; Humans; Immunomodulation; Immunotherapy; Inflammation; Lung Diseases; Metaplasia; Mustard Gas; Pulmonary Disease, Chronic Obstructive; T-Lymphocytes, Regulatory; Th17 Cells

2017
Potential Utility of N-acetylcysteine for Treating Mustard Lung.
    Critical reviews in eukaryotic gene expression, 2017, Volume: 27, Issue:3

    Topics: Acetylcysteine; Apoptosis; Chemical Warfare Agents; Humans; Inflammation; Lung; Lung Diseases; Mustard Gas; Oxidative Stress

2017
A review on proteomics analysis to reveal biological pathways and predictive proteins in sulfur mustard exposed patients: roles of inflammation and oxidative stress.
    Inhalation toxicology, 2019, Volume: 31, Issue:1

    Topics: Chemical Warfare Agents; Humans; Inflammation; Mustard Gas; Mutagens; Oxidative Stress; Proteins; Proteome; Proteomics

2019
Emerging targets for treating sulfur mustard-induced injuries.
    Annals of the New York Academy of Sciences, 2016, Volume: 1374, Issue:1

    Topics: Animals; Blood Coagulation; Humans; Inflammation; Models, Biological; Molecular Targeted Therapy; Mustard Gas; Oxidative Stress

2016
Cellular and molecular mechanisms of acute exposure to sulfur mustard: a systematic review.
    Journal of receptor and signal transduction research, 2017, Volume: 37, Issue:2

    Topics: Cell Death; Chemical Warfare Agents; DNA Damage; DNA Repair; Inflammation; Interleukin-17; Mustard Gas; Oxidative Stress; Signal Transduction

2017
Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 114, Issue:1

    Topics: Administration, Cutaneous; Animals; Chemical Warfare Agents; Inflammation; Inflammation Mediators; Irritants; Models, Animal; Mustard Gas; Protein Array Analysis; Skin; Skin Irritancy Tests

2010
Molecular and cellular mechanism of lung injuries due to exposure to sulfur mustard: a review.
    Inhalation toxicology, 2011, Volume: 23, Issue:7

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Inflammation; Inhalation Exposure; Lung Injury; Mustard Gas; Oxidative Stress; Peptide Hydrolases; Pulmonary Disease, Chronic Obstructive

2011
Baicalin as a potentially promising drug for the management of sulfur mustard induced cutaneous complications: a review of molecular mechanisms.
    Cutaneous and ocular toxicology, 2012, Volume: 31, Issue:3

    Topics: Calcium Signaling; Chemical Warfare Agents; DNA Damage; Flavonoids; Humans; Inflammation; Matrix Metalloproteinases; Mitogen-Activated Protein Kinases; Mustard Gas; Nitric Oxide; Oxidative Stress; Quality of Life; Skin Diseases

2012
Antioxidants countermeasures against sulfur mustard.
    Mini reviews in medicinal chemistry, 2012, Volume: 12, Issue:8

    Topics: Animals; Antioxidants; Chemical Warfare Agents; DNA Damage; Humans; Inflammation; Mustard Gas; Oxidative Stress; Poly(ADP-ribose) Polymerases

2012

Trials

1 trial(s) available for mustard gas and Innate Inflammatory Response

ArticleYear
Short-term Curcuminoid Supplementation for Chronic Pulmonary Complications due to Sulfur Mustard Intoxication: Positive Results of a Randomized Double-blind Placebo-controlled Trial.
    Drug research, 2015, Volume: 65, Issue:11

    Topics: Adult; Anti-Inflammatory Agents; Chemical Warfare Agents; Chronic Disease; Curcumin; Cytokines; Diarylheptanoids; Double-Blind Method; Forced Expiratory Volume; Humans; Inflammation; Inflammation Mediators; Lung Diseases; Male; Middle Aged; Mustard Gas; Pilot Projects; Treatment Outcome; Vital Capacity

2015

Other Studies

50 other study(ies) available for mustard gas and Innate Inflammatory Response

ArticleYear
Limbal stem cell deficiency (LSCD) in rats and mice following whole body exposure to sulfur mustard (SM) vapor.
    Experimental eye research, 2022, Volume: 223

    Topics: Animals; Corneal Diseases; Corneal Injuries; Disease Models, Animal; Eosine Yellowish-(YS); Epithelium, Corneal; Hematoxylin; Humans; Inflammation; Limbus Corneae; Mice; Mustard Gas; Rabbits; Rats; Stem Cells; Toxic Optic Neuropathy

2022
MiR-146a-5p delivered by hucMSC extracellular vesicles modulates the inflammatory response to sulfur mustard-induced acute lung injury.
    Stem cell research & therapy, 2023, 05-30, Volume: 14, Issue:1

    Topics: Extracellular Vesicles; Humans; Inflammation; MicroRNAs; Mustard Gas; TNF Receptor-Associated Factor 6

2023
Pulmonary protective efficacy of S-2[2-aminoethylamino] ethyl phenyl sulphide (DRDE-07) and its analogues against sulfur mustard induced toxicity in mice.
    Environmental toxicology and pharmacology, 2020, Volume: 76

    Topics: Amifostine; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Female; Gene Expression Regulation, Enzymologic; Inflammation; Lung; Lung Diseases; Macrophages; Malondialdehyde; Matrix Metalloproteinase 9; Mice; Mustard Gas; Oxidative Stress

2020
CEES-induced ROS accumulation regulates mitochondrial complications and inflammatory response in keratinocytes.
    Chemico-biological interactions, 2020, Apr-25, Volume: 321

    Topics: Animals; Cell Line; Chemical Warfare Agents; DNA Damage; DNA, Mitochondrial; Humans; Inflammation; Irritants; Keratinocytes; Membrane Potential, Mitochondrial; Mice; Mice, Hairless; Mitochondria; Mustard Gas; Oxidative Stress; Reactive Oxygen Species; Signal Transduction

2020
MicroRNA-mediated inflammation and coagulation effects in rats exposed to an inhaled analog of sulfur mustard.
    Annals of the New York Academy of Sciences, 2020, Volume: 1479, Issue:1

    Topics: Acute Lung Injury; Animals; Blood Coagulation; Chemical Warfare Agents; Early Growth Response Protein 2; Fibroblast Growth Factor 9; Inflammation; Interleukin-1alpha; Interleukin-6; Male; MicroRNAs; Mustard Gas; Rats; Rats, Sprague-Dawley

2020
Progressive Lung Injury, Inflammation, and Fibrosis in Rats Following Inhalation of Sulfur Mustard.
    Toxicological sciences : an official journal of the Society of Toxicology, 2020, 12-01, Volume: 178, Issue:2

    Topics: Animals; Chemical Warfare Agents; Fibrosis; Inflammation; Lung; Lung Injury; Mustard Gas; Oxidative Stress; Rats

2020
In vitro the differences of inflammatory and oxidative reactions due to sulfur mustard induced acute pulmonary injury underlying intraperitoneal injection and intratracheal instillation in rats.
    International immunopharmacology, 2017, Volume: 47

    Topics: Acute Lung Injury; Animals; Cell Adhesion Molecules; Chemical Warfare Agents; China; Cytokines; Dermatologic Agents; Glutathione Peroxidase; Heme Oxygenase-1; Inflammation; Injections, Intraperitoneal; Intubation, Intratracheal; L-Lactate Dehydrogenase; Lethal Dose 50; Male; Mustard Gas; Oxidative Stress; Rats; Rats, Sprague-Dawley

2017
Early oxidative stress, DNA damage and inflammation resulting from subcutaneous injection of sulfur mustard into mice.
    Environmental toxicology and pharmacology, 2017, Volume: 55

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cytokines; Deoxyguanosine; DNA Damage; Gene Expression Regulation; Inflammation; Injections, Subcutaneous; Male; Mice; Mustard Gas; Oxidative Stress; Reactive Oxygen Species

2017
Expression of cytokines and chemokines in mouse skin treated with sulfur mustard.
    Toxicology and applied pharmacology, 2018, 09-15, Volume: 355

    Topics: Animals; Chemical Warfare Agents; Chemokines; Cytokines; Ear, External; Immunohistochemistry; Inflammation; Inflammation Mediators; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 8; Mice; Mustard Gas; RNA; Skin; Skin Diseases

2018
Relevance of Erk1/2-PI3K/Akt signaling pathway in CEES-induced oxidative stress regulates inflammation and apoptosis in keratinocytes.
    Cell biology and toxicology, 2019, Volume: 35, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; Chemical Warfare Agents; DNA Damage; Glutathione; Inflammation; Keratinocytes; Lipid Peroxidation; MAP Kinase Signaling System; Mice; Mice, Hairless; Mitogen-Activated Protein Kinases; Mustard Gas; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction

2019
Evaluation of selective and non-selective cyclooxygenase inhibitors on sulfur mustard-induced pro-inflammatory cytokine formation in normal human epidermal keratinocytes.
    Toxicology letters, 2019, Sep-15, Volume: 312

    Topics: Cell Line; Cyclooxygenase Inhibitors; Cytokines; Gene Expression Regulation; Humans; Inflammation; Keratinocytes; Mustard Gas

2019
Development of a co-culture of keratinocytes and immune cells for in vitro investigation of cutaneous sulfur mustard toxicity.
    Chemico-biological interactions, 2014, Nov-05, Volume: 223

    Topics: Apoptosis; Cell Line; Chemical Warfare Agents; Coculture Techniques; Humans; Inflammation; Interleukin-6; Keratinocytes; Langerhans Cells; Monocytes; Mustard Gas; Necrosis

2014
Increasing NO level regulates apoptosis and inflammation in macrophages after 2-chloroethyl ethyl sulphide challenge.
    The international journal of biochemistry & cell biology, 2017, Volume: 83

    Topics: Animals; Antioxidants; Apoptosis; Cell Cycle Checkpoints; Cell Line; DNA Damage; Humans; Inflammation; Inflammation Mediators; Lipid Peroxidation; Macrophages; Mice; Mice, Hairless; Mustard Gas; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; RAW 264.7 Cells; RNA, Messenger

2017
A novel role of topical iodine in skin: Activation of the Nrf2 pathway.
    Free radical biology & medicine, 2017, Volume: 104

    Topics: Administration, Topical; Animals; Burns; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Interleukin-8; Iodides; Iodine; Mice; Mustard Gas; NF-E2-Related Factor 2; Skin; Ultraviolet Rays

2017
Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 108, Issue:1

    Topics: Administration, Topical; Analysis of Variance; Animals; Apoptosis; Biomarkers, Pharmacological; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermis; Female; Inflammation; Mast Cells; Mice; Mice, Hairless; Mustard Gas; Neutrophil Infiltration; Peroxidase; Proliferating Cell Nuclear Antigen; Random Allocation; Skin

2009
Sulfur mustard induces immune sensitization in hairless guinea pigs.
    International immunopharmacology, 2010, Volume: 10, Issue:2

    Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chemical Warfare Agents; Cytokines; Guinea Pigs; Hypersensitivity, Delayed; Inflammation; Lung; Lymph Nodes; Male; Mustard Gas; Skin

2010
Macrolide antibiotics improve chemotactic and phagocytic capacity as well as reduce inflammation in sulfur mustard-exposed monocytes.
    Pulmonary pharmacology & therapeutics, 2010, Volume: 23, Issue:2

    Topics: Anti-Bacterial Agents; Apoptosis; Cell Line; Chemical Warfare Agents; Chemotaxis; Cytokines; Humans; Inflammation; Inflammation Mediators; Macrolides; Monocytes; Mustard Gas; Nitric Oxide; Nitric Oxide Synthase Type II; Phagocytosis

2010
Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.
    Free radical biology & medicine, 2010, May-01, Volume: 48, Issue:9

    Topics: Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Inflammation; Inhalation Exposure; L-Lactate Dehydrogenase; Lung; Male; Metalloporphyrins; Mustard Gas; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley

2010
Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide.
    Toxicology and applied pharmacology, 2010, Jun-15, Volume: 245, Issue:3

    Topics: Animals; Antioxidants; Cell Line; Chemical Warfare Agents; Dose-Response Relationship, Drug; Eicosanoids; Enzyme Activation; Gene Expression Regulation, Enzymologic; Inflammation; Inflammation Mediators; Irritants; Keratinocytes; Mice; Mitogen-Activated Protein Kinases; Mustard Gas; Oxidative Stress; Protein Carbonylation

2010
Loss of expression of TGF-βs and their receptors in chronic skin lesions induced by sulfur mustard as compared with chronic contact dermatitis patients.
    BMC dermatology, 2011, Jan-14, Volume: 11

    Topics: Adult; Aged; Burns, Chemical; Chemical Warfare; Chemical Warfare Agents; Chronic Disease; Dermatitis, Allergic Contact; Epidermis; Gene Expression; Humans; Inflammation; Iran; Irritants; Male; Middle Aged; Military Personnel; Mustard Gas; Protein Serine-Threonine Kinases; Pruritus; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta1; Transforming Growth Factor beta2

2011
Sodium pyruvate modulates cell death pathways in HaCaT keratinocytes exposed to half-mustard gas.
    International journal of toxicology, 2011, Volume: 30, Issue:2

    Topics: Antioxidants; Apoptosis; Biomarkers; Cells, Cultured; DNA Damage; Drug Combinations; Humans; Inflammation; Keratinocytes; Liposomes; Mustard Gas; Necrosis; Oxidative Stress; Pyruvates; Skin

2011
Investigation of anticholinergic and non-steroidal anti-inflammatory prodrugs which reduce chemically induced skin inflammation.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:2

    Topics: Acetylcholinesterase; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Warfare Agents; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, Animal; Ear; Female; Humans; Inflammation; Irritants; Mice; Mustard Gas; Prodrugs; Skin; Tetradecanoylphorbol Acetate

2012
Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage.
    Experimental and molecular pathology, 2011, Volume: 91, Issue:2

    Topics: Animals; Apoptosis; Biomarkers; Caspase 3; Cell Degranulation; Cell Differentiation; Cyclooxygenase 2; DNA Damage; Histones; Inflammation; Keratinocytes; Keratins; Male; Mast Cells; Mice; Mice, Hairless; Mustard Gas; Peroxidase; Proliferating Cell Nuclear Antigen; Skin; Staining and Labeling; Wound Healing

2011
Nuclear factor κB1/RelA mediates the inflammation and/or survival of human airway exposed to sulfur mustard.
    Journal of receptor and signal transduction research, 2011, Volume: 31, Issue:5

    Topics: Adult; Bronchi; Cell Survival; Epithelial Cells; Humans; Inflammation; Lung; Male; Middle Aged; Mustard Gas; NF-kappa B; Transcription Factor RelA

2011
Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning.
    Toxicology and applied pharmacology, 2012, May-15, Volume: 261, Issue:1

    Topics: Acute-Phase Proteins; Animals; Chemical Warfare Agents; Female; Gene Expression Regulation; Inflammation; Lipocalin-2; Lipocalins; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Mice, Knockout; Mustard Gas; Nitric Oxide Synthase Type II; Oncogene Proteins; Oxidative Stress; Reactive Nitrogen Species; Time Factors; Tumor Necrosis Factor-alpha

2012
Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antidotes; Apoptosis; Cells, Cultured; Chemical Warfare Agents; Cyclooxygenase 2; Deoxyguanosine; DNA Damage; Female; Gene Expression Regulation; Humans; Inflammation; Matrix Metalloproteinase 9; Mice; Mice, Hairless; Mustard Gas; Nitric Oxide Synthase Type II; Oxidative Stress; Signal Transduction; Silybin; Silymarin; Skin

2012
Effect of doxycycline on sulfur mustard-induced respiratory lesions in guinea pigs.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 289, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Chemical Warfare Agents; Doxycycline; Epithelial Cells; Gelatinases; Guinea Pigs; Inflammation; Male; Mustard Gas; Protease Inhibitors; Respiratory System; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2

2005
Skin decontamination of mustards and organophosphates: comparative efficiency of RSDL and Fuller's earth in domestic swine.
    Human & experimental toxicology, 2007, Volume: 26, Issue:2

    Topics: Aluminum Compounds; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Decontamination; Diacetyl; Female; Inflammation; Magnesium Compounds; Mustard Gas; Necrosis; Organothiophosphorus Compounds; Polyethylene Glycols; Silicates; Skin; Sus scrofa

2007
Inhibition of sulfur mustard-induced cytotoxicity and inflammation by the macrolide antibiotic roxithromycin in human respiratory epithelial cells.
    BMC cell biology, 2007, May-24, Volume: 8

    Topics: Anti-Bacterial Agents; Cell Line; Chemical Warfare Agents; Cytokines; Dermatologic Agents; Dose-Response Relationship, Drug; Epithelial Cells; Fluorescent Dyes; Humans; Inflammation; Mustard Gas; Nitric Oxide Synthase Type II; Respiratory Mucosa; Roxithromycin

2007
From topical antidote against skin irritants to a novel counter-irritating and anti-inflammatory peptide.
    Toxicology and applied pharmacology, 2008, Jun-15, Volume: 229, Issue:3

    Topics: Administration, Cutaneous; Animals; Anti-Infective Agents, Local; Cells, Cultured; Dose-Response Relationship, Drug; Guinea Pigs; Histones; Hot Temperature; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred ICR; Mustard Gas; Neutrophils; Oligopeptides; Peptide Fragments; Povidone-Iodine; Protective Agents; Respiratory Burst; Skin; Skin Irritancy Tests; Substance P; Transfection

2008
Histochemical demonstration of hydrogen peroxide production by leukocytes in fixed-frozen tissue sections of inflammatory lesions.
    Journal of leukocyte biology, 1994, Volume: 56, Issue:4

    Topics: Amitrole; Animals; Azides; Catalase; Dermatitis, Contact; Glutathione; Histocytochemistry; Hot Temperature; Hydrogen Peroxide; Hydrogen-Ion Concentration; Inflammation; Leukocytes; Mustard Gas; NADP; Nitric Oxide; Oxidation-Reduction; Rabbits; Superoxides

1994
Rabbit vascular endothelial adhesion molecules: ELAM-1 is most elevated in acute inflammation, whereas VCAM-1 and ICAM-1 predominate in chronic inflammation.
    Journal of leukocyte biology, 1996, Volume: 60, Issue:6

    Topics: Acute Disease; Animals; BCG Vaccine; Chronic Disease; E-Selectin; Endothelium, Vascular; Female; Hypersensitivity, Delayed; Inflammation; Intercellular Adhesion Molecule-1; Leukocyte Count; Leukocytes, Mononuclear; Lymphocyte Function-Associated Antigen-1; Mustard Gas; Neutrophils; Rabbits; Vascular Cell Adhesion Molecule-1; von Willebrand Factor

1996
Dose response of sulphur mustard: behavioral and toxic signs in rats.
    Indian journal of physiology and pharmacology, 1998, Volume: 42, Issue:3

    Topics: Animals; Body Weight; Diarrhea; Dose-Response Relationship, Drug; Inflammation; Male; Mustard Gas; Piloerection; Rats; Rats, Wistar; Salivation; Time Factors

1998
Il-1-related cytokine responses of nonimmune skin cells subjected to CEES exposure with and without potential vesicant antagonists.
    In vitro & molecular toxicology, 2000,Summer, Volume: 13, Issue:2

    Topics: Benzimidazoles; Biomarkers; Calmodulin; Cells, Cultured; Cysteine Proteinase Inhibitors; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Irritants; Keratinocytes; Leupeptins; Mustard Gas; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Receptors, Interleukin-1; Receptors, Interleukin-1 Type II; Sialoglycoproteins

2000
Effects of CEES on inflammatory mediators, heat shock protein 70A, histology and ultrastructure in two skin models.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Biomarkers; Blister; Cell Culture Techniques; Cytokines; Dermatologic Agents; HSP70 Heat-Shock Proteins; Humans; Inflammation; Keratinocytes; Models, Biological; Mustard Gas; Skin; Skin, Artificial

2000
Beneficial effects of topical anti-inflammatory drugs against sulfur mustard-induced ocular lesions in rabbits.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Dermatologic Agents; Dexamethasone; Diclofenac; Eye; Eye Diseases; Inflammation; Mustard Gas; Rabbits; Volatilization

2000
N-acetylcysteine and endothelial cell injury by sulfur mustard.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Acetylcysteine; Animals; Apoptosis; Cattle; Cytokines; Dermatologic Agents; Endothelium; Gene Expression Regulation; Glutathione; Inflammation; Mustard Gas; NF-kappa B

2000
Procedure for assessing myeloperoxidase and inflammatory mediator responses in hairless mouse skin.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Administration, Cutaneous; Animals; Biomarkers; Blood Proteins; Dermatologic Agents; Endpoint Determination; Inflammation; Mice; Mustard Gas; Peroxidase; Specimen Handling

2000
Systemic administration of candidate antivesicants to protect against topically applied sulfur mustard in the mouse ear vesicant model (MEVM).
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Blister; Dermatologic Agents; Dose-Response Relationship, Drug; Ear; Edema; Inflammation; Mice; Mustard Gas; Necrosis; Protective Agents; Steroids

2000
Acute ocular effects of mustard gas: ultrastructural pathology and immunohistopathology of exposed rabbit cornea.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Administration, Cutaneous; Animals; Basement Membrane; Cornea; Dermatologic Agents; Edema; Epithelial Cells; Fibroblasts; Inflammation; Mustard Gas; Necrosis; Rabbits

2000
Sulfur mustard toxicity in macrophages: effect of dexamethasone.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents; Cell Culture Techniques; Cell Survival; Dermatologic Agents; Dexamethasone; DNA; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Inflammation; Macrophages; Macrophages, Alveolar; Mice; Mustard Gas

2000
Response of normal human keratinocytes to sulfur mustard: cytokine release.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Biomarkers; Blister; Cell Culture Techniques; Cytokines; Dermatologic Agents; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Keratinocytes; Mustard Gas; Skin

2000
Inflammatory cytokine response in sulfur mustard-exposed mouse skin.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Cytokines; Dermatologic Agents; Ear; Edema; Inflammation; Inhalation Exposure; Interleukin-6; Mice; Mustard Gas; Skin

2000
Exposure of human epidermal keratinocyte cell cultures to sulfur mustard promotes binding of complement C1q: implications for toxicity and medical countermeasures.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Antigens, Surface; Apoptosis; Binding Sites; Blister; Carrier Proteins; Cell Culture Techniques; Complement C1q; Dermatologic Agents; Humans; Hyaluronan Receptors; Inflammation; Keratinocytes; Membrane Glycoproteins; Mitochondrial Proteins; Mustard Gas; Receptors, Complement; Receptors, Fc

2000
Poly(ADP-ribose) polymerase inhibitors regulate the mechanism of sulfur mustard-initiated cell death in human lymphocytes.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Apoptosis; Cell Membrane; Dermatologic Agents; Humans; Inflammation; Lymphocytes; Mustard Gas; NAD; Poisoning; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protective Agents

2000
Mediators, initiating the inflammatory response, released in organ culture by full-thickness human skin explants exposed to the irritant, sulfur mustard.
    The Journal of investigative dermatology, 1991, Volume: 96, Issue:6

    Topics: Administration, Cutaneous; Dinoprostone; Histamine Release; Humans; Hydrolases; Hydroxyproline; Inflammation; Interleukin-1; L-Lactate Dehydrogenase; Lysosomes; Mast Cells; Mustard Gas; Organ Culture Techniques; Proteins; Skin

1991
Proteases released in organ culture by acute dermal inflammatory lesions produced in vivo in rabbit skin by sulfur mustard: hydrolysis of synthetic peptide substrates for trypsin-like and chymotrypsin-like enzymes.
    Inflammation, 1988, Volume: 12, Issue:4

    Topics: Animals; Blood Proteins; Coumarins; Hydrolysis; Inflammation; Mustard Compounds; Mustard Gas; Oligopeptides; Organ Culture Techniques; Peptide Hydrolases; Phenylalanine; Rabbits; Skin; Substrate Specificity; Wound Healing

1988
Inflammatory mediators and modulators released in organ culture from rabbit skin lesions produced in vivo by sulfur mustard. I. Quantitative histopathology; PMN, basophil, and mononuclear cell survival; and unbound (serum) protein content.
    The American journal of pathology, 1985, Volume: 121, Issue:1

    Topics: Animals; Basophils; Blood Proteins; Cell Count; Cell Survival; Inflammation; Lymphocytes; Macrophages; Mast Cells; Monocytes; Mustard Compounds; Mustard Gas; Neutrophils; Organ Culture Techniques; Protein Binding; Rabbits; Skin

1985
Inflammatory mediators and modulators release in organ culture from rabbit skin lesions produced in vivo by sulfur mustard. II. Evans blue dye experiments that determined the rates of entry and turnover of serum protein in developing and healing lesions.
    The American journal of pathology, 1985, Volume: 121, Issue:1

    Topics: Animals; Blood Proteins; Evans Blue; Inflammation; Mustard Compounds; Mustard Gas; Organ Culture Techniques; Protein Binding; Rabbits; Skin; Wound Healing

1985
Changes in the contents of some rat serum proteins under pathologic conditions. 2. The influence of some further noxious factors in comparison with the effect of ionizing radiation.
    Radiobiologia, radiotherapia, 1974, Volume: 15, Issue:4

    Topics: Animals; Blood Proteins; Burns, Electric; Cobalt Radioisotopes; Endotoxins; Female; Infections; Inflammation; Lipoproteins; Mustard Gas; Radiation Effects; Rats; Turpentine

1974