Page last updated: 2024-08-21

mustard gas and Disease Models, Animal

mustard gas has been researched along with Disease Models, Animal in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (8.45)18.2507
2000's20 (28.17)29.6817
2010's40 (56.34)24.3611
2020's5 (7.04)2.80

Authors

AuthorsStudies
Cohen, M; Dachir, S; Egoz, I; Gez, R; Gutman, H; Horwitz, V; Kadar, T1
Barillo, AR; Barillo, DJ; Croutch, CR; Reid, F; Roseman, J; Thompson, CK1
Ghazanfari, T; Hashemi, SM; Mehdi Naghizadeh, M; Mosaffa, N; Sadeghi, S1
Eisen, MM; Hamilton, TA; Kniffin, DM; Lyman, ME; Mangkhalakhili, MC; McNutt, PM; Nelson, MR; Nguyen, DL; Ondeck, CA; Pagarigan, KT; Wolfe, SE1
Armeli, F; Businaro, R; Laskin, DL; Maggi, E; Murray, A1
Amir, A; Cohen, L; Cohen, M; Dachir, S; Gore, A; Gutman, H; Horwitz, V; Kadar, T1
Chen, Y; Feng, Y; Lin, F; Meng, W; Pei, Z; Shi, W; Sun, M; Xiao, K; Xu, Q; Zhao, J1
Cohen, L; Cohen, M; Dachir, S; Gez, R; Gore, A; Gutman, H; Horwitz, V; Kadar, T1
Jiang, YY; Li, ZS; Xie, JW; Yu, D; Zhong, YX; Zhu, XJ1
Buch, H; Cohen, L; Cohen, M; Dachir, S; Gez, R; Gore, A; Gutman, H; Horwitz, V; Kadar, T1
Beth-Din, A; Cohen, L; Cohen, M; Cohen-Gihon, I; Dachir, S; Egoz, I; Gez, R; Gore, A; Gutman, H; Horwitz, V; Israeli, O; Kadar, T; Zaide, G; Zvi, A1
Fairhall, S; Jenner, J; Jugg, B; Mann, T; Perrott, R; Rutter, S; Salguero, J; Sciuto, AM; Shute, J; Smith, A1
Adkins, A; Glotfelty, E; Hamilton, T; Hughes, J; Lyman, M; McNutt, P; Nelson, M; Tuznik, K1
Amir, A; Brandeis, R; Cohen, L; Cohen, M; Dachir, S; Fishbine, E; Gore, A; Gutman, H; Horwitz, V; Kadar, T; Turetz, J1
Babin, MC; Casillas, RP; Cervelli, JA; Composto, GM; Gerecke, DR; Heck, DE; Joseph, LB; Laskin, DL; Laskin, JD; Sinko, PJ1
Ghanei, M; Karimzadeh, I; Khalili, H; Saburi, A; Shohrati, M1
Bakdouri, NE; Batal, M; Bertoni, M; Boudry, I; Cléry-Barraud, C; Douki, T; Emorine, S; Mouret, S; Peinnequin, A; Poyot, T; Wartelle, J1
Anderson, DR; Garlick, RB; Hendry-Hofer, TB; Holmes, WW; Houin, PR; Loader, JE; Paradiso, DC; Rancourt, RC; Rioux, JS; Smith, RW; Veress, LA; White, CW1
Beaslas, O; Hildebrand, RB; Lammers, B; Olkkonen, VM; Van Berkel, TJ; Van Eck, M; van Kampen, E1
Chao, Z; Chengjin, L; Haibo, C; Rui, X; Shengming, Z; Tao, W; Wenjun, G; Xiao, M; Xiaoji, Z1
Ji, P; Ju, LY; Wang, M; Wang, T; Yang, H; Zhao, J; Zhong, Y; Zhu, S; Zhu, X1
Glotfelty, EJ; Hamilton, TA; Lyman, ME; McNutt, PM; Nelson, MR; Tuznik, KM1
Ben-Sasson, S; Ben-Yehuda Greenwald, M; Bianco-Peled, H; Frušić-Zlotkin, M; Kohen, R; Soroka, Y1
Chilcott, RP; Chipman, JK; Dalton, CH; Graham, JS; Hall, CA; Lydon, HL1
Deckert, RR; Graham, JS; Hamilton, TA; Lee, RB; Mitcheltree, LW; Schiavetta, AM; Stevenson, RS1
Smith, WJ1
Amir, A; Brandeis, R; Buch, H; Cohen, L; Cohen, M; Dachir, S; Fishbine, E; Gutman, H; Horwitz, V; Kadar, T; Sahar, R; Solomon, A; Turetz, J1
Agarwal, R; Gu, M; Orlicky, DJ; Pal, A; Rana, S; Tewari-Singh, N; White, CW1
Kehe, K; Thiermann, H1
Das, SK; Mukherjee, S; Mukhopadhyay, S; Smith, M; Stone, WL1
Allon, N; Amir, A; Dachir, S; Kadar, T; Manisterski, E; Rabinovitz, I1
Graham, JS; McDougal, JN; Price, JA; Reid, FM; Rogers, JV; Shaw, MQ1
Benson, JM; Blair, LF; Cheng, YS; Grotendorst, GR; Irvin, CM; Kracko, DA; Lehman, MR; McDonald, JD; Weber, WM; White, RK1
Brandies, R; Cohen, M; Dachir, S; Fishbeine, E; Horwitz, V; Kadar, T; Sahar, R1
Breton, P; Daulon, S; Dorandeu, F; Foquin, A; Lallement, G; Perrier, N; Taysse, L1
Boudry, I; Cruz, C; Daulon, S; Dorandeu, F; Foquin, A; Hérodin, F; Lallement, G; Mathieu, J; Taysse, L1
Hendry-Hofer, TB; Loader, JE; O'Neill, HC; Rancourt, RC; Veress, LA; White, CW1
Loke, WK; Ng, ET; Sim, MK1
Fairhall, SJ; Jenner, J; Jugg, BJ; Mann, TM; Read, RW; Rutter, SJ; Sciuto, AM; Smith, AJ; Stubbs, SJ1
Agarwal, R; Jain, AK; Orlicky, DJ; Tewari-Singh, N; White, CW1
Fabio, KM; Flowers, RA; Guillon, CD; Harman, MP; Heck, DE; Heindel, ND; Huang, MT; Laskin, JD; Saxena, J; Vetrano, AM; Young, SC1
Deb, U; Jadhav, SE; Lomash, V; Pant, SC; Rai, R; Vijayaraghavan, R1
Cheng, YS; Cox, CE; Grotendorst, GR; Kracko, DA; Lehman, MR; McDonald, JD; Weber, WM1
Ghanei, M; Harandi, AA1
Amnuaysirikul, J; Anderson, DR; Brown, AW; Chua, AL; Gao, X; Holmes, WW; Lin, H; Ray, P1
Guo, X; Hendry-Hofer, TB; Jones, TN; Rancourt, RC; Veress, LA; White, CW1
Adkins, A; Hamilton, T; Lawrence, R; McNutt, P; Milhorn, D; Nelson, M; Swartz, A1
Jadhav, SE; Lomash, V; Pant, SC; Vijayaraghavan, R1
Arlaud, C; Boudry, I; Cléry-Barraud, C; Coulon, D; Four, E; Nguon, N; Sentenac, C; Vallet, V1
Loke, WK; Tang, FR1
Beach, SL; Dillman, JF; Hilber, DJ; Jarecke, AJ; Rothwell, CC; Ruff, AL1
Amir, A; Brandeis, R; Cohen, L; Cohen, M; Dachir, S; Gutman, H; Horwitz, V; Kadar, T1
Garlick, RB; Hendry-Hofer, TB; Loader, JE; Rioux, JS; Veress, LA; White, CW1
Brodsky, B; Casillas, RP; Nyska, A; Sintov, A; Wormser, U1
Rice, P1
Diemel, RV; Kuijpers, WC; van Helden, HP1
Cai, Y; Hu, W; Jiang, P; Ma, Q; Yuan, W; Zhang, L; Zhao, J; Zhu, M1
Brown, RF; Evison, D; Rice, P1
Graham, JS; Niemuth, NA; Reid, FM; Shumaker, SM; Waugh, JD1
Castagna, MP; Gordon, RK; Isidore, MA; Nambiar, MP; Steele, KE1
Graham, JS; Hurst, CG; Moeller, RB; Okerberg, CV; Skelton, H; Smith, KJ1
Lindsay, CD; Rice, P1
Casillas, R; Graham, J; Hackley, BE; Skelton, HG; Smith, KJ; Stemler, F1
Kjellström, BT; Persson, JK; Runn, P1
Oglesby-Megee, S; Petrali, JP1
Bennett, NJ; Brown, RF; Chilcott, RP; Lam, DG; Rice, P1
Brown, RF; Chilcott, RP; Rice, P1
Conley, J; Hamilton, M; Hunter, K; Lundy, P; Sawyer, TW1
Brodsky, B; Nyska, A; Sintov, A; Wormser, U1
Amir, A; Barness, I; Chapman, S; Fishbeine, E; Kadar, T; Liani, H; Meshulam, Y; Sahar, R1
Braue, EH; Mershon, MM; Mitcheltree, LW; Petrali, JP; Wade, JV1

Reviews

7 review(s) available for mustard gas and Disease Models, Animal

ArticleYear
Nutraceuticals as potential therapeutics for vesicant-induced pulmonary fibrosis.
    Annals of the New York Academy of Sciences, 2020, Volume: 1480, Issue:1

    Topics: Animals; Chemical Warfare Agents; Dietary Supplements; Disease Models, Animal; Humans; Irritants; Mechlorethamine; Mustard Gas; Pulmonary Fibrosis

2020
The role of N-acetylcysteine in the management of acute and chronic pulmonary complications of sulfur mustard: a literature review.
    Inhalation toxicology, 2014, Volume: 26, Issue:9

    Topics: Acetylcysteine; Animals; Bronchiolitis Obliterans; Chemical Warfare Agents; Disease Models, Animal; Humans; Lung; Mustard Gas; Oxidative Stress; Randomized Controlled Trials as Topic

2014
Contributions of tissue-specific pathologies to corneal injuries following exposure to SM vapor.
    Annals of the New York Academy of Sciences, 2016, Volume: 1374, Issue:1

    Topics: Animals; Cornea; Corneal Injuries; Disease Models, Animal; Environmental Exposure; Humans; Mustard Gas; Volatilization

2016
Therapeutic options to treat sulfur mustard poisoning--the road ahead.
    Toxicology, 2009, Sep-01, Volume: 263, Issue:1

    Topics: Acute Disease; Animals; Chemical Warfare Agents; Dermatologic Agents; Disease Models, Animal; Humans; Mustard Gas; Poisoning; Skin Absorption; Skin Diseases

2009
Molecular and cellular mechanism of lung injuries due to exposure to sulfur mustard: a review.
    Inhalation toxicology, 2011, Volume: 23, Issue:7

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Inflammation; Inhalation Exposure; Lung Injury; Mustard Gas; Oxidative Stress; Peptide Hydrolases; Pulmonary Disease, Chronic Obstructive

2011
Sulfur mustard and respiratory diseases.
    Critical reviews in toxicology, 2012, Volume: 42, Issue:8

    Topics: Animals; Bronchiolitis Obliterans; Chemical Warfare Agents; Disease Models, Animal; E-Selectin; Glutathione; Humans; Iran; Iraq; Lung Neoplasms; Mustard Gas; Nitric Oxide Synthase; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Pulmonary Fibrosis; Respiratory System; World War I

2012
Sulphur mustard injuries of the skin. Pathophysiology and management.
    Toxicological reviews, 2003, Volume: 22, Issue:2

    Topics: Animals; Burns, Chemical; Chemical Warfare Agents; Disease Models, Animal; Humans; Mustard Gas; Skin

2003

Other Studies

64 other study(ies) available for mustard gas and Disease Models, Animal

ArticleYear
Limbal stem cell deficiency (LSCD) in rats and mice following whole body exposure to sulfur mustard (SM) vapor.
    Experimental eye research, 2022, Volume: 223

    Topics: Animals; Corneal Diseases; Corneal Injuries; Disease Models, Animal; Eosine Yellowish-(YS); Epithelium, Corneal; Hematoxylin; Humans; Inflammation; Limbus Corneae; Mice; Mustard Gas; Rabbits; Rats; Stem Cells; Toxic Optic Neuropathy

2022
Debridement of Sulfur Mustard Skin Burns: A Comparison of Three Methods.
    Journal of burn care & research : official publication of the American Burn Association, 2020, 01-30, Volume: 41, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bandages; Burns, Chemical; Chemical Warfare Agents; Debridement; Disease Models, Animal; Laser Therapy; Lasers, Solid-State; Mafenide; Mustard Gas; Swine; Swine, Miniature; Wound Healing

2020
The immunomodulatory effects of mesenchymal stem cells on long term pulmonary complications in an animal model exposed to a sulfur mustard analog.
    International immunopharmacology, 2020, Volume: 80

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Differentiation; Chemical Warfare Agents; Cytokines; Disease Models, Animal; Immunologic Factors; Lung; Lung Diseases; Macrophages, Alveolar; Male; Mesenchymal Stem Cells; Mice, Inbred C57BL; Mustard Gas

2020
Corneal Endothelial Cell Toxicity Determines Long-Term Outcome After Ocular Exposure to Sulfur Mustard Vapor.
    Cornea, 2020, Volume: 39, Issue:5

    Topics: Animals; Basement Membrane; Corneal Injuries; Disease Models, Animal; Disease Progression; Endothelium, Corneal; Female; Follow-Up Studies; Mustard Gas; Rabbits; Time Factors

2020
Ocular Surface Changes After Sulfur Mustard Exposure in Rabbits, Monitored by Impression Cytology.
    Cornea, 2017, Volume: 36, Issue:8

    Topics: Animals; Burns, Chemical; Cell Count; Chemical Warfare Agents; Conjunctiva; Cornea; Disease Models, Animal; Epithelium, Corneal; Eye Burns; Female; Goblet Cells; Limbus Corneae; Mustard Gas; Rabbits

2017
Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subsequent Nrf2 pathway activation.
    Scientific reports, 2017, 08-25, Volume: 7, Issue:1

    Topics: Animals; Disease Models, Animal; Gene Expression; Hydrogen Sulfide; Kelch-Like ECH-Associated Protein 1; Lung; Mice; Mustard Gas; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Protein Transport; Reactive Oxygen Species; Signal Transduction; Sulfides

2017
Successful single treatment with ziv-aflibercept for existing corneal neovascularization following ocular chemical insult in the rabbit model.
    Experimental eye research, 2018, Volume: 171

    Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Burns, Chemical; Chemical Warfare Agents; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Female; Mustard Gas; Rabbits; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Treatment Outcome; Vascular Endothelial Growth Factor A

2018
Changes in inflammatory factors and protein expression in sulfur mustard (1LD
    International immunopharmacology, 2018, Volume: 61

    Topics: Acute Lung Injury; Administration, Inhalation; Animals; Chemical Warfare Agents; Cytokines; Disease Models, Animal; Injections, Intraperitoneal; Male; Mitogen-Activated Protein Kinases; Mustard Gas; NF-kappa B; Pulmonary Alveoli; Rats, Sprague-Dawley

2018
Differential expression of corneal and limbal cytokines and chemokines throughout the clinical course of sulfur mustard induced ocular injury in the rabbit model.
    Experimental eye research, 2018, Volume: 177

    Topics: Acute Disease; Animals; Burns, Chemical; Chemical Warfare Agents; Chemokines; Cornea; Corneal Injuries; Cytokines; Disease Models, Animal; Eye Burns; Limbus Corneae; Mustard Gas; Rabbits

2018
A comprehensive analysis of corneal mRNA levels during sulfur mustard induced ocular late pathology in the rabbit model using RNA sequencing.
    Experimental eye research, 2019, Volume: 184

    Topics: Animals; Chemical Warfare Agents; Cornea; Corneal Neovascularization; Corneal Opacity; Disease Models, Animal; Mustard Gas; Rabbits; RNA, Messenger

2019
N-acetyl-L-cysteine protects against inhaled sulfur mustard poisoning in the large swine.
    Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:4

    Topics: Acetylcysteine; Administration, Inhalation; Aerosols; Animals; Antidotes; Antioxidants; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Disease Models, Animal; Expectorants; Female; Gas Poisoning; Lung; Lung Diseases; Mustard Gas; Neutrophil Infiltration; Random Allocation; Respiratory Insufficiency; Survival Analysis; Sus scrofa

2013
Structural, morphological, and functional correlates of corneal endothelial toxicity following corneal exposure to sulfur mustard vapor.
    Investigative ophthalmology & visual science, 2013, Oct-15, Volume: 54, Issue:10

    Topics: Animals; Cell Membrane Permeability; Chemical Warfare Agents; Corneal Diseases; Disease Models, Animal; Disease Progression; Endothelium, Corneal; Eye Injuries; Female; Microscopy, Confocal; Microscopy, Electron, Scanning; Mustard Gas; Rabbits

2013
The beneficial effects of doxycycline, an inhibitor of matrix metalloproteinases, on sulfur mustard-induced ocular pathologies depend on the injury stage.
    Current eye research, 2014, Volume: 39, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Burns, Chemical; Corneal Injuries; Disease Models, Animal; Doxycycline; Eye Burns; Female; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mustard Gas; Ophthalmic Solutions; Rabbits; Wound Healing

2014
Structural changes in hair follicles and sebaceous glands of hairless mice following exposure to sulfur mustard.
    Experimental and molecular pathology, 2014, Volume: 96, Issue:3

    Topics: Animals; Apoptosis; Caspase 3; Cell Differentiation; Cell Proliferation; Disease Models, Animal; DNA Damage; Down-Regulation; Epithelial Cells; Galectin 3; Hair Follicle; Histones; Keratinocytes; Male; Mice; Mice, Hairless; Mustard Gas; Receptor, Fibroblast Growth Factor, Type 2; Sebaceous Glands; Skin; Wound Healing

2014
Time course of skin features and inflammatory biomarkers after liquid sulfur mustard exposure in SKH-1 hairless mice.
    Toxicology letters, 2015, Jan-05, Volume: 232, Issue:1

    Topics: Animals; Biomarkers; Burns, Chemical; Cell Degranulation; Chemical Warfare Agents; Dermatitis, Contact; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Inflammation Mediators; Laminin; Male; Mast Cells; Matrix Metalloproteinase 9; Mice, Hairless; Mustard Gas; Neutrophils; RNA, Messenger; Skin; Time Factors

2015
Airway tissue plasminogen activator prevents acute mortality due to lethal sulfur mustard inhalation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 143, Issue:1

    Topics: Acidosis; Administration, Inhalation; Airway Obstruction; Animals; Chemical Warfare Agents; Disease Models, Animal; Drug Administration Schedule; Fibrinolytic Agents; Inhalation Exposure; Lung; Male; Mustard Gas; Oxygen; Pulmonary Ventilation; Rats, Sprague-Dawley; Respiration; Respiratory Insufficiency; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator

2015
Orp8 deficiency in bone marrow-derived cells reduces atherosclerotic lesion progression in LDL receptor knockout mice.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Atherosclerosis; ATP Binding Cassette Transporter 1; Biomarkers; Bone Marrow Cells; Cholesterol; Cytokines; Disease Models, Animal; Female; Foam Cells; Gene Expression; Inflammation Mediators; Leukocyte Count; Macrophages; Male; Mice; Mice, Knockout; Mustard Gas; Plaque, Atherosclerotic; Receptors, LDL; Receptors, Steroid; Time Factors; Triglycerides

2014
Mechanism underlying acute lung injury due to sulfur mustard exposure in rats.
    Toxicology and industrial health, 2016, Volume: 32, Issue:8

    Topics: Acute Lung Injury; Alkylating Agents; Alveolar Epithelial Cells; Animals; Apoptosis; Biomarkers; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Disease Models, Animal; DNA Damage; Endoplasmic Reticulum, Rough; Lung; Lymphocyte Activation; Male; Microscopy, Electron, Transmission; Microvilli; Mitochondria; Mustard Gas; Oxidative Stress; Rats, Sprague-Dawley; Respiratory Mucosa; Specific Pathogen-Free Organisms

2016
[Morphological assessment of sulfur mustard-induced acute lung injury in rats through different routes].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2015, Volume: 33, Issue:9

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Lung; Male; Mustard Gas; Peritoneum; Pulmonary Alveoli; Rats; Trachea

2015
A novel role of topical iodine in skin: Activation of the Nrf2 pathway.
    Free radical biology & medicine, 2017, Volume: 104

    Topics: Administration, Topical; Animals; Burns; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Interleukin-8; Iodides; Iodine; Mice; Mustard Gas; NF-E2-Related Factor 2; Skin; Ultraviolet Rays

2017
The percutaneous toxicokinetics of Sulphur mustard in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant.
    Journal of applied toxicology : JAT, 2017, Volume: 37, Issue:9

    Topics: Animals; Chemical Warfare Agents; Decontamination; Disease Models, Animal; Female; Intestine, Small; Kidney; Liver; Mustard Gas; Skin; Skin Absorption; Swine; Toxicokinetics

2017
Medical management of cutaneous sulfur mustard injuries.
    Toxicology, 2009, Sep-01, Volume: 263, Issue:1

    Topics: Administration, Cutaneous; Animals; Cells, Cultured; Chemical Warfare Agents; Debridement; Dermatologic Agents; Disease Models, Animal; Female; Mustard Gas; Poisoning; Skin; Skin Absorption; Skin Diseases; Skin Transplantation; Swine; Water; Wound Healing

2009
Ocular injuries following sulfur mustard exposure--pathological mechanism and potential therapy.
    Toxicology, 2009, Sep-01, Volume: 263, Issue:1

    Topics: Adult Stem Cells; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Warfare Agents; Corneal Diseases; Corneal Edema; Corneal Neovascularization; Corneal Opacity; Dexamethasone; Disease Models, Animal; Doxycycline; Drug Combinations; Enzyme Inhibitors; Female; Instillation, Drug; Limbus Corneae; Matrix Metalloproteinase Inhibitors; Mustard Gas; Neomycin; Rabbits

2009
Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 108, Issue:1

    Topics: Administration, Topical; Analysis of Variance; Animals; Apoptosis; Biomarkers, Pharmacological; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermis; Female; Inflammation; Mast Cells; Mice; Mice, Hairless; Mustard Gas; Neutrophil Infiltration; Peroxidase; Proliferating Cell Nuclear Antigen; Random Allocation; Skin

2009
Clinical picture of sulfur mustard poisoning.
    Toxicology, 2009, Sep-01, Volume: 263, Issue:1

    Topics: Animals; Chemical Warfare Agents; Disease Models, Animal; Humans; Mustard Gas; Poisoning

2009
Role of MAPK/AP-1 signaling pathway in the protection of CEES-induced lung injury by antioxidant liposome.
    Toxicology, 2009, Jul-10, Volume: 261, Issue:3

    Topics: Acetylcysteine; Activating Transcription Factors; Animals; Antidotes; Antioxidants; Blood Proteins; Cell Proliferation; Cyclin D1; Disease Models, Animal; Erythrocytes; Guinea Pigs; Liposomes; Lung; Lung Injury; Male; Mitogen-Activated Protein Kinases; Mustard Gas; Neutrophil Infiltration; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pulmonary Eosinophilia; Time Factors; Tocopherols; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2009
Inhalation exposure to sulfur mustard in the guinea pig model: clinical, biochemical and histopathological characterization of respiratory injuries.
    Toxicology and applied pharmacology, 2009, Dec-01, Volume: 241, Issue:2

    Topics: Alkylating Agents; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Inhalation Exposure; Lethal Dose 50; Lung Injury; Mustard Gas; Respiratory Mucosa; Spectroscopy, Fourier Transform Infrared

2009
Transcriptional changes in porcine skin at 7 days following sulfur mustard and thermal burn injury.
    Cutaneous and ocular toxicology, 2009, Volume: 28, Issue:3

    Topics: Animals; Burns; Burns, Chemical; Disease Models, Animal; Female; Gene Expression Profiling; Mustard Gas; Oligonucleotide Array Sequence Analysis; Principal Component Analysis; Skin; Sus scrofa; Transcription, Genetic; Wound Healing

2009
Inhalation exposure systems for the development of rodent models of sulfur mustard-induced pulmonary injury.
    Toxicology mechanisms and methods, 2010, Volume: 20, Issue:1

    Topics: Aerosols; Animals; Chemical Warfare Agents; Disease Models, Animal; Female; Inhalation Exposure; Intubation, Intratracheal; Lung; Lung Diseases; Mustard Gas; Particle Size; Pilot Projects; Rats; Rats, Inbred F344; Turbinates; Volatilization

2010
Characterization of acute and long-term sulfur mustard-induced skin injuries in hairless guinea-pigs using non-invasive methods.
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2010, Volume: 16, Issue:1

    Topics: Acute Disease; Animals; Biopsy; Blister; Chronic Disease; Dermatitis, Contact; Dermatologic Agents; Disease Models, Animal; Erythema; Guinea Pigs; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mustard Gas; Skin; Skin Absorption; Water

2010
Cutaneous challenge with chemical warfare agents in the SKH-1 hairless mouse (II): effects of some currently used skin decontaminants (RSDL and Fuller's earth) against liquid sulphur mustard and VX exposure.
    Human & experimental toxicology, 2011, Volume: 30, Issue:6

    Topics: Aluminum Compounds; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Decontamination; Diacetyl; Disease Models, Animal; Magnesium Compounds; Male; Mice; Mice, Hairless; Mustard Gas; Organothiophosphorus Compounds; Polyethylene Glycols; Silicates; Skin

2011
Cutaneous challenge with chemical warfare agents in the SKH-1 hairless mouse. (I) Development of a model for screening studies in skin decontamination and protection.
    Human & experimental toxicology, 2011, Volume: 30, Issue:6

    Topics: Animals; Chemical Warfare Agents; Decontamination; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Mice; Mice, Hairless; Mustard Gas; Organothiophosphorus Compounds; Skin; Skin Tests

2011
Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation.
    American journal of respiratory and critical care medicine, 2010, Dec-01, Volume: 182, Issue:11

    Topics: Airway Obstruction; Animals; Blotting, Western; Bronchi; Bronchoalveolar Lavage Fluid; Capillary Permeability; Chemical Warfare Agents; Disease Models, Animal; Fibrin; Immunoglobulin M; Inhalation Exposure; Male; Microdissection; Microscopy, Confocal; Mustard Gas; Rats; Rats, Sprague-Dawley

2010
Protective actions of des-aspartate-angiotensin I in mice model of CEES-induced lung intoxication.
    Journal of applied toxicology : JAT, 2011, Volume: 31, Issue:6

    Topics: Angiotensin I; Animals; Bronchoalveolar Lavage Fluid; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Epoprostenol; Intercellular Adhesion Molecule-1; Losartan; Lung; Male; Mice; Mice, Inbred BALB C; Mustard Gas; NADPH Oxidases; Peroxidase; Reactive Oxygen Species; Receptors, Immunologic; Signal Transduction

2011
Exposure-response effects of inhaled sulfur mustard in a large porcine model: a 6-h study.
    Inhalation toxicology, 2010, Volume: 22, Issue:14

    Topics: Acute Lung Injury; Age Factors; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inhalation Exposure; Mustard Gas; Oxyhemoglobins; Respiratory Mucosa; Swine; Time Factors

2010
2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin.
    Toxicology, 2011, Apr-11, Volume: 282, Issue:3

    Topics: Animals; Blister; Chemical Warfare Agents; Dermatitis, Contact; Disease Models, Animal; Immunohistochemistry; Male; Mast Cells; Mice; Mice, Hairless; Mustard Gas; Organ Size; Peroxidase; Skin

2011
Investigation of anticholinergic and non-steroidal anti-inflammatory prodrugs which reduce chemically induced skin inflammation.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:2

    Topics: Acetylcholinesterase; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Warfare Agents; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, Animal; Ear; Female; Humans; Inflammation; Irritants; Mice; Mustard Gas; Prodrugs; Skin; Tetradecanoylphorbol Acetate

2012
Designing of mouse model: a new approach for studying sulphur mustard-induced skin lesions.
    Burns : journal of the International Society for Burn Injuries, 2011, Volume: 37, Issue:5

    Topics: Acetone; Animals; Blood Cell Count; Body Weight; Burns, Chemical; Chemical Warfare Agents; Disease Models, Animal; Glutathione; Kidney; Lipid Peroxidation; Liver; Mice; Mustard Gas; Skin; Spleen

2011
Dermal and ocular exposure systems for the development of models of sulfur mustard-induced injury.
    Toxicology mechanisms and methods, 2011, Volume: 21, Issue:7

    Topics: Animals; Blister; Burns, Chemical; Chemical Warfare Agents; Disease Models, Animal; Eye Burns; Guinea Pigs; Mustard Gas; Rabbits; Skin; Skin Absorption; Time Factors; Volatilization

2011
Pathological studies on the protective effect of a macrolide antibiotic, roxithromycin, against sulfur mustard inhalation toxicity in a rat model.
    Toxicologic pathology, 2011, Volume: 39, Issue:7

    Topics: Acute Lung Injury; Animals; Bronchi; Disease Models, Animal; Histocytochemistry; Inhalation Exposure; Male; Mustard Gas; Protective Agents; Pulmonary Alveoli; Rats; Research Design; Roxithromycin; Trachea

2011
Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Airway Obstruction; Animals; Antigens, Surface; Bronchi; Bronchoalveolar Lavage Fluid; Cell Line, Transformed; Chemical Warfare Agents; Disease Models, Animal; Epithelial Cells; Factor VII; Factor Xa; Humans; Inhalation Exposure; Male; Milk Proteins; Mustard Gas; Proteins; Rats; Rats, Sprague-Dawley; Thromboplastin; Time Factors

2012
Pathogenesis of acute and delayed corneal lesions after ocular exposure to sulfur mustard vapor.
    Cornea, 2012, Volume: 31, Issue:3

    Topics: Acute Disease; Animals; Chemical Warfare Agents; Corneal Diseases; Corneal Edema; Disease Models, Animal; Disease Progression; Gas Chromatography-Mass Spectrometry; Mustard Gas; Rabbits

2012
Time course pathogenesis of sulphur mustard-induced skin lesions in mouse model.
    International wound journal, 2013, Volume: 10, Issue:4

    Topics: Animals; Biopsy, Needle; Blister; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-6; Mice; Mice, Inbred Strains; Mustard Gas; Nitric Oxide Synthase Type III; Random Allocation; Risk Assessment; Time Factors; Transforming Growth Factor alpha

2013
Sulfur mustard cutaneous injury characterization based on SKH-1 mouse model: relevance of non-invasive methods in terms of wound healing process analyses.
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2013, Volume: 19, Issue:1

    Topics: Administration, Cutaneous; Animals; Body Water; Chemical Warfare Agents; Disease Models, Animal; Elasticity; Erythema; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Hairless; Mustard Gas; Skin; Skin Diseases; Water Loss, Insensible; Wound Healing

2013
Development of a mouse model for sulfur mustard-induced ocular injury and long-term clinical analysis of injury progression.
    Cutaneous and ocular toxicology, 2013, Volume: 32, Issue:2

    Topics: Animals; Chemical Warfare Agents; Cytokines; Disease Models, Animal; Disease Progression; Epithelium, Corneal; Eye Injuries; Female; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mustard Gas; Neovascularization, Physiologic; Vascular Cell Adhesion Molecule-1

2013
Prolonged impairment of corneal innervation after exposure to sulfur mustard and its relation to the development of delayed limbal stem cell deficiency.
    Cornea, 2013, Volume: 32, Issue:4

    Topics: Animals; Calcitonin Gene-Related Peptide; Chemical Warfare Agents; Cornea; Corneal Diseases; Disease Models, Animal; Female; Limbus Corneae; Mustard Gas; Ophthalmic Nerve; Rabbits; Stem Cells

2013
Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction.
    American journal of respiratory cell and molecular biology, 2013, Volume: 48, Issue:4

    Topics: Airway Obstruction; Animals; Chemical Warfare Agents; Disease Models, Animal; Fibrin; Fibrinolytic Agents; Humans; Mustard Gas; Rats; Rats, Sprague-Dawley; Respiratory Insufficiency; Tissue Plasminogen Activator

2013
Protective effect of topical iodine containing anti-inflammatory drugs against sulfur mustard-induced skin lesions.
    Archives of toxicology, 2004, Volume: 78, Issue:3

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Chemical Warfare Agents; Clobetasol; Disease Models, Animal; Drug Combinations; Ear Diseases; Edema; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Mustard Gas; Piroxicam; Povidone-Iodine; Protective Agents; Skin; Skin Diseases; Skin Irritancy Tests; Time Factors

2004
Asthmalike symptoms following intratracheal exposure of Guinea pigs to sulfur mustard aerosol: therapeutic efficacy of exogenous lung surfactant curosurf and salbutamol.
    Inhalation toxicology, 2004, Volume: 16, Issue:8

    Topics: Aerosols; Albuterol; Animals; Asthma; Biological Products; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Chemical Warfare Agents; Disease Models, Animal; Guinea Pigs; Intubation, Intratracheal; Lethal Dose 50; Lung; Male; Mustard Gas; Phospholipids; Respiratory Function Tests; Specific Pathogen-Free Organisms; Surface Tension; Trachea

2004
[Therapeutic effects of rhEPO, rhG-CSF on sulfur mustard induced toxicity in dogs].
    Wei sheng yan jiu = Journal of hygiene research, 2004, Volume: 33, Issue:6

    Topics: Animals; Blood Cell Count; Disease Models, Animal; Dogs; Drug Therapy, Combination; Erythropoietin; Granulocyte Colony-Stimulating Factor; Mustard Gas; Poisoning; Recombinant Proteins

2004
The treatment of sulphur mustard burns with laser debridement.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2006, Volume: 59, Issue:10

    Topics: Animals; Burns, Chemical; Chemical Warfare Agents; Debridement; Disease Models, Animal; Epithelium; Female; Laser Therapy; Mustard Gas; Regeneration; Swine; Wound Healing

2006
Biomechanical monitoring of cutaneous sulfur mustard-induced lesions in the weanling pig model for depth of injury.
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2007, Volume: 13, Issue:2

    Topics: Animals; Biomechanical Phenomena; Disease Models, Animal; Female; Mustard Gas; Severity of Illness Index; Skin; Skin Diseases; Swine

2007
A dorsal model for cutaneous vesicant injury by 2-chloroethyl ethyl sulfide using C57BL/6 mice.
    Cutaneous and ocular toxicology, 2007, Volume: 26, Issue:3

    Topics: Animals; Body Weight; Chemical Warfare Agents; Dermatitis; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Erythema; Irritants; Male; Mice; Mice, Inbred C57BL; Motor Activity; Mustard Gas; Necrosis; Severity of Illness Index; Skin Pigmentation; Time Factors; Wound Healing

2007
Histopathologic features seen in sulfur mustard induced cutaneous lesions in hairless guinea pigs.
    Journal of cutaneous pathology, 1995, Volume: 22, Issue:3

    Topics: Animals; Chemical Warfare Agents; Disease Models, Animal; Guinea Pigs; Mustard Gas; Skin; Skin Diseases

1995
Changes in connective tissue macromolecular components of Yucatan mini-pig skin following application of sulphur mustard vapour.
    Human & experimental toxicology, 1995, Volume: 14, Issue:4

    Topics: Animals; Basement Membrane; Blister; Collagen; Connective Tissue; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Immunohistochemistry; Laminin; Mustard Gas; Skin; Swine; Swine, Miniature

1995
Histopathologic features seen with different animal models following cutaneous sulfur mustard exposure.
    Journal of dermatological science, 1997, Volume: 14, Issue:2

    Topics: Animals; Blister; Disease Models, Animal; Guinea Pigs; Humans; Irritants; Keratinocytes; Male; Mice; Mice, Hairless; Mice, Nude; Mustard Gas; Skin; Species Specificity; Swine; Transplantation, Heterologous

1997
Surgical treatment of skin lesions induced by sulfur mustard ("mustard gas")--an experimental study in the guinea pig.
    Annals of the Academy of Medicine, Singapore, 1997, Volume: 26, Issue:1

    Topics: Animals; Chemical Warfare Agents; Disease Models, Animal; Guinea Pigs; Male; Mustard Gas; Photomicrography; Skin; Skin Diseases; Skin Transplantation; Survival Rate; Wound Healing

1997
Toxicity of mustard gas skin lesions.
    Microscopy research and technique, 1997, May-01, Volume: 37, Issue:3

    Topics: Animals; Chemical Warfare Agents; Dermatitis, Irritant; Disease Models, Animal; Guinea Pigs; Humans; Immunohistochemistry; Mustard Gas; Skin Diseases, Vesiculobullous

1997
Dermabrasion--a novel concept in the surgical management of sulphur mustard injuries.
    Burns : journal of the International Society for Burn Injuries, 2000, Volume: 26, Issue:1

    Topics: Animals; Burns, Chemical; Dermabrasion; Disease Models, Animal; Mustard Gas; Skin; Swine; Swine, Miniature; Treatment Outcome; Wound Healing

2000
Non-invasive quantification of skin injury resulting from exposure to sulphur mustard and Lewisite vapours.
    Burns : journal of the International Society for Burn Injuries, 2000, Volume: 26, Issue:3

    Topics: Animals; Arsenicals; Burns, Chemical; Chemical Warfare; Dermatologic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Environmental Exposure; Environmental Monitoring; Female; Injury Severity Score; Mustard Gas; Skin; Swine; Water Loss, Insensible

2000
Domestic swine model for the assessment of chemical warfare agent-anesthetic interactions: some effects of sulfur mustard.
    Military medicine, 2000, Volume: 165, Issue:8

    Topics: Anesthesia, General; Anesthetics; Animals; Apnea; Chemical Warfare; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Drug Monitoring; Halothane; Humans; Ketamine; Male; Military Medicine; Mustard Gas; Neuromuscular Agents; Seizures; Succinylcholine; Swine; Time Factors

2000
Topical iodine preparation as therapy against sulfur mustard-induced skin lesions.
    Toxicology and applied pharmacology, 2000, Nov-15, Volume: 169, Issue:1

    Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Dermatologic Agents; Disease Models, Animal; Drug Interactions; Guinea Pigs; Irritants; Lidocaine; Male; Mustard Gas; Povidone-Iodine; Skin; Skin Diseases; Time Factors

2000
Treatment of skin injuries induced by sulfur mustard with calmodulin antagonists, using the pig model.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Administration, Topical; Anesthetics, Local; Animals; Blister; Calmodulin; Dermatologic Agents; Disease Models, Animal; Dopamine Antagonists; Female; Injections, Intradermal; Lidocaine; Mustard Gas; Procaine; Swine; Thioridazine; Trifluoperazine

2000
Hairless guinea pig bioassay model for vesicant vapor exposures.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1990, Volume: 15, Issue:3

    Topics: Animals; Blister; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Guinea Pigs; Irritants; Male; Mustard Gas; Volatilization

1990