muscimol has been researched along with Urinary Bladder, Overactive in 2 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Urinary Bladder, Overactive: Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. URINARY INCONTINENCE may or may not be present.
| Excerpt | Relevance | Reference |
|---|---|---|
| "At 4 weeks after Th9-10 spinal cord transection awake cystometry and recordings of external urethral sphincter electromyogram were performed to examine the effect of intrathecal application of the gamma-aminobutyric acid A and B agonists muscimol and baclofen or the gamma-aminobutyric acid A and B antagonists bicuculline and saclofen (Tocris Cookson, Ellisville, Missouri), respectively, at the level of the L6-S1 spinal cord." | 1.35 | GABA receptor activation in the lumbosacral spinal cord decreases detrusor overactivity in spinal cord injured rats. ( Chancellor, MB; de Groat, WC; Hiragata, S; Miyazato, M; Sasatomi, K; Sugaya, K; Yoshimura, N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vignes, JR | 1 |
| Deloire, MS | 1 |
| Petry, KG | 1 |
| Nagy, F | 1 |
| Miyazato, M | 1 |
| Sasatomi, K | 1 |
| Hiragata, S | 1 |
| Sugaya, K | 1 |
| Chancellor, MB | 1 |
| de Groat, WC | 1 |
| Yoshimura, N | 1 |
2 other studies available for muscimol and Urinary Bladder, Overactive
| Article | Year |
|---|---|
Characterization and restoration of altered inhibitory and excitatory control of micturition reflex in experimental autoimmune encephalomyelitis in rats.
Topics: Animals; Baclofen; Bicuculline; Cauda Equina; Efferent Pathways; Electric Stimulation; Encephalomyel | 2007 |
GABA receptor activation in the lumbosacral spinal cord decreases detrusor overactivity in spinal cord injured rats.
Topics: Animals; Baclofen; Bicuculline; Disease Models, Animal; Female; GABA Agonists; GABA Antagonists; Glu | 2008 |