muscimol has been researched along with Tremor in 8 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Harmaline-induced tremor in rodents is a model of essential tremor." | 7.75 | Pharmacological characterization of harmaline-induced tremor activity in mice. ( Foreman, MM; Hanania, T; Malekiani, SA; Olivier, B; Paterson, NE, 2009) |
| "Intraperitoneal injection of ethanol (1-2 g/kg) and chlordiazepoxide (2-16 mg/kg) suppressed susceptibility to audiogenically induced, clonic-tonic seizures and antagonized forelimb tremor in rats undergoing ethanol withdrawal, 30 min after treatment." | 7.66 | Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. ( Breese, GR; Frye, GD; McCown, TJ, 1983) |
| "Harmaline-induced tremor in rodents is a model of essential tremor." | 3.75 | Pharmacological characterization of harmaline-induced tremor activity in mice. ( Foreman, MM; Hanania, T; Malekiani, SA; Olivier, B; Paterson, NE, 2009) |
| "The effects of four tremorgenic and one nontremorgenic mycotoxins were studied on gamma-aminobutyric acid (GABAA) receptor binding and function in rat brain and on binding of a voltage-operated Cl- channel in Torpedo electric organ." | 3.67 | Action of tremorgenic mycotoxins on GABAA receptor. ( Cole, RJ; Eldefrawi, AT; Eldefrawi, ME; Gant, DB; Valdes, JJ, 1987) |
| "Intraperitoneal injection of ethanol (1-2 g/kg) and chlordiazepoxide (2-16 mg/kg) suppressed susceptibility to audiogenically induced, clonic-tonic seizures and antagonized forelimb tremor in rats undergoing ethanol withdrawal, 30 min after treatment." | 3.66 | Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. ( Breese, GR; Frye, GD; McCown, TJ, 1983) |
| "The tremor was accompanied by coherent oscillations in the local field potential (LFP)." | 1.48 | Loss of Balance between Striatal Feedforward Inhibition and Corticostriatal Excitation Leads to Tremor. ( Bar-Gad, I; Oran, Y, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oran, Y | 1 |
| Bar-Gad, I | 1 |
| Paterson, NE | 1 |
| Malekiani, SA | 1 |
| Foreman, MM | 1 |
| Olivier, B | 1 |
| Hanania, T | 1 |
| Bichard, AR | 1 |
| Little, HJ | 1 |
| Frye, GD | 1 |
| McCown, TJ | 1 |
| Breese, GR | 1 |
| Penn, RD | 1 |
| Kroin, JS | 1 |
| Reinkensmeyer, A | 1 |
| Corcos, DM | 1 |
| Plotkin, G | 1 |
| Nandi, D | 1 |
| Aziz, TZ | 1 |
| Liu, X | 1 |
| Stein, JF | 1 |
| Gant, DB | 1 |
| Cole, RJ | 1 |
| Valdes, JJ | 1 |
| Eldefrawi, ME | 1 |
| Eldefrawi, AT | 1 |
1 review available for muscimol and Tremor
| Article | Year |
|---|---|
Brainstem motor loops in the control of movement.
Topics: Animals; Bicuculline; Brain Stem; Electric Stimulation; GABA Agonists; GABA Antagonists; Humans; Mac | 2002 |
7 other studies available for muscimol and Tremor
| Article | Year |
|---|---|
Loss of Balance between Striatal Feedforward Inhibition and Corticostriatal Excitation Leads to Tremor.
Topics: Adamantane; Animals; Basal Ganglia Diseases; Cerebral Cortex; Corpus Striatum; Evoked Potentials; Fe | 2018 |
Pharmacological characterization of harmaline-induced tremor activity in mice.
Topics: Affect; Animals; Anticonvulsants; Baclofen; Behavior, Animal; Benzazepines; Carbolines; Chlordiazepo | 2009 |
Drugs that increase gamma-aminobutyric acid transmission protect against the high pressure neurological syndrome.
Topics: Anesthetics; Animals; Bicuculline; Body Temperature; Flurazepam; gamma-Aminobutyric Acid; Male; Mice | 1982 |
Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors.
Topics: 4-Aminobutyrate Transaminase; Acoustic Stimulation; Aminobutyrates; Animals; Chlordiazepoxide; Disea | 1983 |
Injection of GABA-agonist into globus pallidus in patient with Parkinson's disease.
Topics: Adult; GABA Agonists; Globus Pallidus; Humans; Injections, Intralesional; Male; Muscimol; Parkinson | 1998 |
Grasping essential tremor.
Topics: Clozapine; GABA Agonists; GABA Antagonists; Humans; Muscimol; Tremor | 1999 |
Action of tremorgenic mycotoxins on GABAA receptor.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Elect | 1987 |