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muscimol and Tachycardia

muscimol has been researched along with Tachycardia in 8 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

Research Excerpts

ExcerptRelevanceReference
" In urethane-anaesthetised rats, stimulation of neurons in the perifornical area by microinjection of bicuculline or 6-OH-saclofen causes tachycardia and inhibits baroreflex bradycardia."3.69Ethanol inhibition of stress-related tachycardia involves medullary NMDA receptors. ( Kunos, G; Lovas, G; Palkovits, M; Varga, K, 1996)
"Thus, DMH-induced tachycardia is mediated through activation of neurons in the area of the RP, suggesting that these neurons may play a previously unrecognized role in stress-induced cardiac stimulation."1.31Tachycardia evoked by disinhibition of the dorsomedial hypothalamus in rats is mediated through medullary raphe. ( DiMicco, JA; Samuels, BC; Zaretsky, DV, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abreu, AR1
de Abreu, AR1
Santos, LT1
de Souza, AA1
da Silva, LG1
Chianca, DA1
de Menezes, RC1
Chitravanshi, VC1
Kawabe, K1
Sapru, HN1
Nakamura, K1
Morrison, SF1
Zaretsky, DV2
Zaretskaia, MV1
Samuels, BC2
Cluxton, LK1
DiMicco, JA2
McDougall, SJ1
Widdop, RE1
Lawrence, AJ1
Salomé, N1
Ngampramuan, S1
Nalivaiko, E1
Varga, K1
Lovas, G1
Palkovits, M1
Kunos, G1

Other Studies

8 other studies available for muscimol and Tachycardia

ArticleYear
Blunted GABA-mediated inhibition within the dorsomedial hypothalamus potentiates the cardiovascular response to emotional stress in rats fed a high-fat diet.
    Neuroscience, 2014, Mar-14, Volume: 262

    Topics: Animals; Arterial Pressure; Bicuculline; Diet, High-Fat; Emotions; GABA-A Receptor Agonists; GABA-A

2014
GABA and glycine receptors in the nucleus ambiguus mediate tachycardia elicited by chemical stimulation of the hypothalamic arcuate nucleus.
    American journal of physiology. Heart and circulatory physiology, 2015, Jul-01, Volume: 309, Issue:1

    Topics: Animals; Arcuate Nucleus of Hypothalamus; GABA Antagonists; GABA-A Receptor Agonists; Glycine Agents

2015
Central efferent pathways for cold-defensive and febrile shivering.
    The Journal of physiology, 2011, Jul-15, Volume: 589, Issue:Pt 14

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adipose Tissue, Brown; Animals; Blood Pressure; Body Tempera

2011
Microinjection of muscimol into raphe pallidus suppresses tachycardia associated with air stress in conscious rats.
    The Journal of physiology, 2003, Jan-01, Volume: 546, Issue:Pt 1

    Topics: Air; Animals; Baroreflex; GABA Agonists; Male; Microinjections; Muscimol; Raphe Nuclei; Rats; Rats,

2003
Medial prefrontal cortical integration of psychological stress in rats.
    The European journal of neuroscience, 2004, Volume: 20, Issue:9

    Topics: Amygdala; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Dorsomedial Hypothalamic

2004
Intra-amygdala injection of GABAA agonist, muscimol, reduces tachycardia and modifies cardiac sympatho-vagal balance during restraint stress in rats.
    Neuroscience, 2007, Aug-24, Volume: 148, Issue:2

    Topics: Amygdala; Analysis of Variance; Animals; Area Under Curve; Functional Laterality; GABA Agonists; Hea

2007
Ethanol inhibition of stress-related tachycardia involves medullary NMDA receptors.
    European journal of pharmacology, 1996, Aug-29, Volume: 310, Issue:2-3

    Topics: Animals; Baclofen; Bicuculline; Ethanol; GABA Agonists; GABA Antagonists; Male; Muscimol; Rats; Rats

1996
Tachycardia evoked by disinhibition of the dorsomedial hypothalamus in rats is mediated through medullary raphe.
    The Journal of physiology, 2002, Feb-01, Volume: 538, Issue:Pt 3

    Topics: Animals; Bicuculline; Cardiovascular System; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonis

2002