muscimol has been researched along with Supranuclear Palsy, Progressive in 2 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Supranuclear Palsy, Progressive: A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohashi, T | 1 |
| Waitzman, DM | 1 |
| Silakov, VL | 1 |
| DePalma-Bowles, S | 1 |
| Ayers, AS | 1 |
2 other studies available for muscimol and Supranuclear Palsy, Progressive
| Article | Year |
|---|---|
[Neuron group of rostral midbrain associated with selective vertical gaze palsy in alert cats].
Topics: Action Potentials; Animals; Arousal; Cats; Eye Movements; Mesencephalon; Muscimol; Neurons; Supranuc | 1995 |
Effects of reversible inactivation of the primate mesencephalic reticular formation. II. Hypometric vertical saccades.
Topics: Animals; Feedback; GABA Agonists; Head Movements; Macaca mulatta; Mesencephalon; Microinjections; Mu | 2000 |