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muscimol and Stomach Ulcer

muscimol has been researched along with Stomach Ulcer in 2 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Research Excerpts

ExcerptRelevanceReference
"Effects of systemically administered gamma-aminobutyric acid (GABA) on indomethacin-induced gastric ulceration were studied in rats."7.67Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors. ( Hara, S; Morioka, S; Satoh, K; Yanagihara, S, 1988)
"The occurrence and characteristics of binding sites specific for gamma-aminobutyric acid (GABA) and muscimol in the rat stomach were examined by biochemical and autoradiographic techniques, and the effects of GABAergic model compounds on gastric ulceration induced by chemical irritation was studied in intact and unilaterally vagotomized rats."3.67GABAA receptors in the rat stomach may mediate mucoprotective effects. ( Amenta, F; Erdö, SL; Ezer, E; Matuz, J; Wolff, JR, 1989)
"Effects of systemically administered gamma-aminobutyric acid (GABA) on indomethacin-induced gastric ulceration were studied in rats."3.67Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors. ( Hara, S; Morioka, S; Satoh, K; Yanagihara, S, 1988)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erdö, SL1
Ezer, E1
Matuz, J1
Wolff, JR1
Amenta, F1
Hara, S1
Yanagihara, S1
Satoh, K1
Morioka, S1

Other Studies

2 other studies available for muscimol and Stomach Ulcer

ArticleYear
GABAA receptors in the rat stomach may mediate mucoprotective effects.
    European journal of pharmacology, 1989, Jun-08, Volume: 165, Issue:1

    Topics: Administration, Oral; Aminooxyacetic Acid; Animals; Anti-Ulcer Agents; Baclofen; Bicuculline; Bindin

1989
Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors.
    Japanese journal of pharmacology, 1988, Volume: 47, Issue:4

    Topics: Animals; Anticonvulsants; Atropine; beta-Alanine; Bicuculline; Drug Synergism; gamma-Aminobutyric Ac

1988