Page last updated: 2024-10-31

muscimol and Pyrexia

muscimol has been researched along with Pyrexia in 16 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Research Excerpts

ExcerptRelevanceReference
"Theophylline-associated convulsions are frequently exacerbated by fever, but the mechanisms behind it are still not completely understood."3.77Effect of heat exposure on aminophylline-induced convulsions in mice. ( Araki, H; Kawasaki, H; Ochi, R; Suemaru, K; Takechi, K; Watanabe, S; Yamaguchi, T, 2011)
"Effects of hyperthermia-induced seizures (HS) on GABAA and benzodiazepine (BDZ) receptor binding in immature rat brain were evaluated using in vitro autoradiography."1.33Hyperthermia-induced seizures modify the GABAA and benzodiazepine receptor binding in immature rat brain. ( Feria, A; González-Ramírez, M; Orozco, S; Rocha, L; Salgado, H, 2005)
"Fever is the widely known hallmark of disease and is induced by the action of the nervous system."1.31The rostral raphe pallidus nucleus mediates pyrogenic transmission from the preoptic area. ( Kaneko, T; Katoh, H; Kobayashi, S; Matsumura, K; Nakamura, K; Negishi, M, 2002)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's2 (12.50)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tanaka, M1
McKinley, MJ1
McAllen, RM1
Zaretsky, DV1
Zaretskaia, MV1
Durant, PJ1
Rusyniak, DE1
Wellman, LL1
Fitzpatrick, ME1
Hallum, OY1
Sutton, AM1
Williams, BL1
Sanford, LD1
Chen, F1
Dworak, M1
Wang, Y1
Cham, JL1
Badoer, E1
Cao, WH1
Madden, CJ1
Morrison, SF2
Ochi, R1
Suemaru, K1
Watanabe, S1
Yamaguchi, T1
Takechi, K1
Kawasaki, H1
Araki, H1
Nakamura, K2
González-Ramírez, M1
Orozco, S1
Salgado, H1
Feria, A1
Rocha, L2
González Ramírez, M1
Orozco Suárez, S1
Salgado Ceballos, H1
Feria Velasco, A1
Osaka, T1
Ootsuka, Y1
Blessing, WW1
Steiner, AA1
Romanovsky, AA1
DeFeudis, FV1
Monda, M2
Amaro, S1
Sullo, A1
De Luca, B1
Osborne, PG1
Onoe, H1
Watanabe, Y1
Viggiano, A1
De Luca, V1
Matsumura, K1
Kaneko, T1
Kobayashi, S1
Katoh, H1
Negishi, M1

Reviews

1 review available for muscimol and Pyrexia

ArticleYear
Involvement of GABA and other inhibitory amino acids in thermoregulation.
    General pharmacology, 1984, Volume: 15, Issue:6

    Topics: Allylglycine; Amino Acids; Animals; Body Temperature Regulation; Brain; Fever; gamma-Aminobutyric Ac

1984

Other Studies

15 other studies available for muscimol and Pyrexia

ArticleYear
Role of an excitatory preoptic-raphé pathway in febrile vasoconstriction of the rat's tail.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Dec-15, Volume: 305, Issue:12

    Topics: Animals; Dinoprostone; Excitatory Amino Acid Antagonists; Fever; Glycine; Kynurenic Acid; Male; Micr

2013
Treadmill running restores MDMA-mediated hyperthermia prevented by inhibition of the dorsomedial hypothalamus.
    Brain research, 2015, May-22, Volume: 1608

    Topics: Analysis of Variance; Animals; Body Temperature; Exercise Test; Fever; GABA-A Receptor Agonists; Hal

2015
Individual Differences in Animal Stress Models: Considering Resilience, Vulnerability, and the Amygdala in Mediating the Effects of Stress and Conditioned Fear on Sleep.
    Sleep, 2016, 06-01, Volume: 39, Issue:6

    Topics: Adaptation, Psychological; Amygdala; Animals; Conditioning, Psychological; Disease Models, Animal; E

2016
Role of the hypothalamic PVN in the reflex reduction in mesenteric blood flow elicited by hyperthermia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:6

    Topics: Animals; Blood Pressure; Body Temperature; Disease Models, Animal; Down-Regulation; Fever; GABA Agon

2008
Inhibition of brown adipose tissue thermogenesis by neurons in the ventrolateral medulla and in the nucleus tractus solitarius.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:1

    Topics: Adipose Tissue, Brown; Animals; Bicuculline; Body Temperature; Cardiovascular System; Cold Temperatu

2010
Effect of heat exposure on aminophylline-induced convulsions in mice.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:5

    Topics: Aminophylline; Animals; Dizocilpine Maleate; Fever; Male; Mice; Muscimol; Seizures; Theophylline

2011
Central efferent pathways for cold-defensive and febrile shivering.
    The Journal of physiology, 2011, Jul-15, Volume: 589, Issue:Pt 14

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adipose Tissue, Brown; Animals; Blood Pressure; Body Tempera

2011
Hyperthermia-induced seizures modify the GABAA and benzodiazepine receptor binding in immature rat brain.
    Cellular and molecular neurobiology, 2005, Volume: 25, Issue:6

    Topics: Animals; Animals, Newborn; Autoradiography; Brain; Child; Female; Fever; Flunitrazepam; GABA Agonist

2005
Hyperthermia-induced seizures modify the GABA(A) and benzodiazepine receptor binding in immature rat brain.
    Cellular and molecular neurobiology, 2007, Volume: 27, Issue:2

    Topics: Age Factors; Animals; Autoradiography; Brain; Female; Fever; Flunitrazepam; GABA Agonists; GABA Modu

2007
Prostaglandin E(2) fever mediated by inhibition of the GABAergic transmission in the region immediately adjacent to the organum vasculosum of the lamina terminalis.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 456, Issue:5

    Topics: Animals; Bicuculline; Body Temperature; Dinoprostone; Dose-Response Relationship, Drug; Fever; GABA

2008
Fever response to intravenous prostaglandin E2 is mediated by the brain but does not require afferent vagal signaling.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:4

    Topics: Adipose Tissue, Brown; Animals; Body Temperature; Brain; Carbon Dioxide; Dinoprostone; Disease Model

2008
Injection of muscimol in the posterior hypothalamus reduces the PGE1-hyperthermia in the rat.
    Brain research bulletin, 1995, Volume: 37, Issue:6

    Topics: Adipose Tissue; Alprostadil; Animals; Body Temperature; Colon; Electric Stimulation; Fever; Heart Ra

1995
GABAergic system inducing hyperthermia in the rat preoptic area: its independence of prostaglandin E2 system.
    Brain research, 1994, Oct-24, Volume: 661, Issue:1-2

    Topics: Analysis of Variance; Animals; Bicuculline; Body Temperature; Dinoprostone; Dose-Response Relationsh

1994
Administration of muscimol into the posterior hypothalamus reduces hyperthermia induced by hippocampal neostigmine injection.
    Brain research, 2000, Dec-29, Volume: 887, Issue:2

    Topics: Adipose Tissue, Brown; Animals; Body Temperature; Colon; Fever; Hippocampus; Hypothalamus, Posterior

2000
The rostral raphe pallidus nucleus mediates pyrogenic transmission from the preoptic area.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Jun-01, Volume: 22, Issue:11

    Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Cell Count; Dinoprostone; Fever; Fluore

2002