Page last updated: 2024-10-31

muscimol and Pregnancy

muscimol has been researched along with Pregnancy in 72 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"White rats were subjected to REM-sleep deprivation during 14-20 days of pregnancy."5.28[The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy]. ( Zabludovskiĭ, AL; Zhulin, VV, 1989)
"Prenatal exposure to valproic acid (VPA) enhances the risk for later development of autism spectrum disorders (ASD)."3.85Increased GABAA receptor binding in amygdala after prenatal administration of valproic acid to rats. ( Bertelsen, F; Drasbek, KR; Folloni, D; Landau, AM; Møller, A; Scheel-Krüger, J, 2017)
" We here examined autoradiographic binding of [(3)H]muscimol to measure the total population of GABA(A) receptors and [(3)H]flunitrazepam to assess density of benzodiazepine sites in the medial prefrontal cortex, bed nucleus of the stria terminalis, amygdala, hippocampus, and periaqueductal gray of female rats sacrificed on day 7 postpartum, day 10 of pregnancy, or as diestrous virgins."3.77Autoradiographic analysis of GABAA receptor binding in the neural anxiety network of postpartum and non-postpartum laboratory rats. ( Lonstein, JS; Miller, SM, 2011)
"The sensitivity of prenatal protein malnourished rats to the amnestic properties of the direct GABAA receptor agonist muscimol and the selective benzodiazepine (BZ) receptor agonist, CL218,872, was studied in the male offspring of rats provided with a protein deficient diet (6% casein) for 5 weeks prior to mating and throughout pregnancy."3.72Spatial learning deficits induced by muscimol and CL218,872: lack of effect of prenatal malnutrition. ( Bonnie, KE; Duran, P; Galler, JR; Hudson, JL; Shultz, PL; Tonkiss, J, 2003)
"The abundance of gamma-aminobutyric acid receptor type A (GABAA receptor) subunit mRNAs and polypeptides as well as muscimol-stimulated 36Cl- uptake were measured in rat cerebral cortex or hippocampus at various times during pregnancy and after delivery."3.70Molecular and functional adaptation of the GABA(A) receptor complex during pregnancy and after delivery in the rat brain. ( Biggio, G; Concas, A; Floris, S; Follesa, P; Mostallino, MC; Tuligi, G, 1998)
"Pregnancy increases affinity of [3H]muscimol binding to GABAA receptors in the rat forebrain."3.67Pregnancy-induced alterations of GABAA receptor sensitivity in maternal brain: an antecedent of post-partum 'blues'? ( Falkay, G; Ford-Rice, F; Majewska, MD, 1989)
"Binding of a GABAA receptor agonist, [3H]muscimol, was studied in rat uterine membranes of non-pregnant rats and those at days 15 and 19 of pregnancy."3.67Modulation of uterine GABAA receptors during gestation and by tetrahydroprogesterone. ( Baulieu, EE; Falkay, G; Majewska, MD, 1989)
"Muscimol was administered twice on d14 and twice on d15 (1 h prior to each lipopolysaccharide injection; 0."1.39Muscimol delays lipopolysaccharide-induced preterm delivery in mice: role of GABA(A) receptors and nitric oxide. ( Dehpour, AR; Fakhraei, N; Gharedaghi, MH; Javadi-Paydar, M; Javadian, P; Salehi-Sadaghiani, M; Tavangar, SM; Yousefzadeh-Fard, Y, 2013)
"Muscimol treatment in the saline-exposed group increased the mount and intromission latencies."1.38Maternal exposure to picrotoxin modifies the response of the GABAA receptor during sexual behavior of adult male rat offspring. ( Baso, AC; Bernardi, MM; Felicio, LF; Kirsten, TB; Prosdocimi, FC; Teodorov, E, 2012)
"Gadolinium is a rare-earth lanthanide metal ion and is used as organic gadolinium complexes in magnetic resonance imaging (MRI)."1.35Inhibition of chloride outward transport by gadolinium in cultured rat spinal cord neurons. ( Hirao, K; Ishibashi, H; Nabekura, J; Yamaguchi, J, 2009)
"Pretreatment with muscimol, a GABAA receptor agonist, over a concentration range of 0."1.33Chronic stimulation of GABAA receptor with muscimol reduces amyloid beta protein (25-35)-induced neurotoxicity in cultured rat cortical cells. ( Ban, JY; Lee, BY; Seong, YH, 2005)
"Thymol is a naturally occurring phenolic monoterpene known for its anti-microbial and anti-oxidant properties."1.33Allosteric positive interaction of thymol with the GABAA receptor in primary cultures of mouse cortical neurons. ( Bujons, J; García, DA; Suñol, C; Vale, C, 2006)
"Effects of hyperthermia-induced seizures (HS) on GABAA and benzodiazepine (BDZ) receptor binding in immature rat brain were evaluated using in vitro autoradiography."1.33Hyperthermia-induced seizures modify the GABAA and benzodiazepine receptor binding in immature rat brain. ( Feria, A; González-Ramírez, M; Orozco, S; Rocha, L; Salgado, H, 2005)
"Bicuculline treatment led to a disorganized distribution of GnRH cells in the forebrain and a concomitant dissociation of GnRH cells from fibers of guidance."1.31Effects of gamma-aminobutyric acid(A) receptor manipulation on migrating gonadotropin-releasing hormone neurons through the entire migratory route in vivo and in vitro. ( Bless, EP; Schwarting, GA; Tobet, SA; Westaway, WA, 2000)
"The muscimol treatment, however, did not mimic the effects of perinatal estrogen treatment."1.28GABAergic influence on the development of the sexually dimorphic nucleus of male and female rats. ( Bach, F; Flügge, G; Wuttke, W, 1992)
"Phenobarbital (PhB) was administered to pregnant mice during days 9-18 of gestation."1.28Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors. ( Fares, F; Gavish, M; Pick, CG; Weizman, A; Yanai, J, 1990)
"White rats were subjected to REM-sleep deprivation during 14-20 days of pregnancy."1.28[The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy]. ( Zabludovskiĭ, AL; Zhulin, VV, 1989)
"[3H]muscimol was used for the labeling of GABA receptors and [3H]flunitrazepam for benzodiazepine receptors."1.26Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study. ( Kuhar, MJ; Palacios, JM, 1981)

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-199020 (27.78)18.7374
1990's15 (20.83)18.2507
2000's27 (37.50)29.6817
2010's8 (11.11)24.3611
2020's2 (2.78)2.80

Authors

AuthorsStudies
Aghighi Bidgoli, F1
Salami, M1
Talaei, SA1
Vacher, CM1
Lacaille, H1
O'Reilly, JJ1
Salzbank, J1
Bakalar, D1
Sebaoui, S1
Liere, P1
Clarkson-Paredes, C1
Sasaki, T1
Sathyanesan, A1
Kratimenos, P1
Ellegood, J1
Lerch, JP1
Imamura, Y1
Popratiloff, A1
Hashimoto-Torii, K1
Gallo, V1
Schumacher, M1
Penn, AA1
Delhaes, F1
Fournier, S1
Tolsa, JF1
Peyter, AC1
Bairam, A1
Kinkead, R1
Shi, Z1
Cassaglia, PA1
Gotthardt, LC1
Brooks, VL1
Bradford, AB1
Mancini, JD1
Atchison, WD1
Bertelsen, F1
Møller, A1
Folloni, D1
Drasbek, KR1
Scheel-Krüger, J1
Landau, AM1
Ishibashi, H1
Hirao, K1
Yamaguchi, J1
Nabekura, J1
Sanderson, JL1
Donald Partridge, L1
Valenzuela, CF1
du Bois, TM1
Deng, C1
Han, M1
Newell, KA1
Huang, XF1
Bortone, D1
Polleux, F1
Zhou, R1
Bai, Y1
Yang, R1
Zhu, Y1
Chi, X1
Li, L1
Chen, L2
Sokabe, M1
Miller, SM1
Lonstein, JS1
Gharedaghi, MH1
Javadi-Paydar, M1
Yousefzadeh-Fard, Y1
Salehi-Sadaghiani, M1
Javadian, P1
Fakhraei, N1
Tavangar, SM1
Dehpour, AR1
Bernardi, MM1
Kirsten, TB1
Teodorov, E1
Baso, AC1
Prosdocimi, FC1
Felicio, LF1
Soria, JM1
Valdeolmillos, M1
Schomberg, SL1
Bauer, J1
Kintner, DB1
Su, G1
Flemmer, A1
Forbush, B1
Sun, D1
Nuñez, JL2
McCarthy, MM2
Tonkiss, J1
Shultz, PL1
Bonnie, KE1
Hudson, JL1
Duran, P1
Galler, JR1
Lee, BY1
Ban, JY1
Seong, YH1
Bambrick, LL1
Krueger, BK1
García, DA1
Bujons, J1
Vale, C1
Suñol, C1
González-Ramírez, M1
Orozco, S1
Salgado, H1
Feria, A1
Rocha, L2
Galanopoulou, AS1
González Ramírez, M1
Orozco Suárez, S1
Salgado Ceballos, H1
Feria Velasco, A1
Heida, JG1
Velísková, J1
Moshé, SL1
Racagni, G2
Apud, JA2
Cocchi, D2
Locatelli, V2
Iuliano, E2
Casanueva, F1
Müller, EE2
Hösli, E3
Möhler, H1
Richards, JG1
Hösli, L3
Massotti, M1
Alleva, FR1
Balazs, T1
Guidotti, A1
Sarliève, LL1
DeFeudis, FV1
Ossola, L1
Varga, V1
Mandel, P1
Shibla, DB1
Gardell, MA1
Neale, JH1
Palacios, JM2
Kuhar, MJ2
Johnston, BM1
Gluckman, PD2
Brooksbank, BW1
Atkinson, DJ1
Balázs, R1
Koff, JM1
Miller, LG3
Rage, F1
Jalaguier, S1
Rougeot, C1
Tapia-Arancibia, L1
Fiszman, ML1
Behar, T1
Lange, GD2
Smith, SV2
Novotny, EA2
Barker, JL2
Follesa, P2
Floris, S1
Tuligi, G1
Mostallino, MC2
Concas, A2
Biggio, G2
Mienville, JM1
Porcu, P1
Barbaccia, ML1
Trabucchi, M1
Purdy, RH1
Grisenti, P1
Blaine, K1
Gasser, K1
Conway, S1
Bless, EP1
Westaway, WA1
Schwarting, GA1
Tobet, SA1
Tkachuk, SS1
Pishak, VP1
Myslyts'kyĭ, VF1
Moore, JP1
Wray, S1
Ricceri, L1
Venerosi, A1
Valanzano, A1
Sorace, A1
Alleva, E1
Luk, KC1
Sadikot, AF1
Fujii, E1
Mellon, SH1
Altmann, L1
Mundy, WR1
Ward, TR1
Fastabend, A1
Lilienthal, H1
Bailey, CD1
Brien, JF1
Reynolds, JN1
Otsuka, T1
Hashida, M1
Oka, T1
Kaba, H1
Briner, W1
Grobin, AC1
Morrow, AL1
Miachon, S1
Augier, S1
Jouvenet, M1
Boucher, P1
Vallon, JJ1
Niehoff, DL1
Licht, P1
Harbarth, P1
Merz, WE1
Bach, F1
Flügge, G2
Wuttke, W2
Chesley, S1
Lumpkin, M1
Schatzki, A1
Galpern, WR1
Greenblatt, DJ1
Shader, RI1
Jarolimek, W1
Misgeld, U1
Mandler, RN1
Schaffner, AE1
Redle, S1
Rojas, J1
Schramek, H1
Fares, F1
Weizman, A1
Pick, CG1
Yanai, J1
Gavish, M1
Bisset, GW1
Chowdrey, HS1
Fairhall, KM1
Gunn, LK1
Majewska, MD2
Ford-Rice, F1
Falkay, G2
Zhulin, VV2
Zabludovskiĭ, AL2
Roy, RB1
Weill, CL1
Lopez, F1
Baulieu, EE1
Ruiz, G1
Hamon, M1
Vergé, D1
Rothe, T1
Middleton-Price, H1
Bigl, V1
Fuchs, E1

Reviews

1 review available for muscimol and Pregnancy

ArticleYear
Anterior pituitary GABA receptors in relation to prolactin secretion.
    Advances in biochemical psychopharmacology, 1983, Volume: 37

    Topics: Animals; Diestrus; Estradiol; Female; gamma-Aminobutyric Acid; Lactation; Muscimol; Picrotoxin; Pitu

1983

Other Studies

71 other studies available for muscimol and Pregnancy

ArticleYear
Environmental enrichment restores impaired spatial memory and synaptic plasticity in prenatally stress exposed rats: The role of GABAergic neurotransmission.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2020, Volume: 80, Issue:7

    Topics: Animals; Bicuculline; Corticosterone; Environment; Female; GABA-A Receptor Agonists; GABA-A Receptor

2020
Placental endocrine function shapes cerebellar development and social behavior.
    Nature neuroscience, 2021, Volume: 24, Issue:10

    Topics: Aldehyde Reductase; Animals; Autism Spectrum Disorder; Cerebellum; Endocrine Glands; Female; GABA Ag

2021
Consequences of gestational stress on GABAergic modulation of respiratory activity in developing newborn pups.
    Respiratory physiology & neurobiology, 2014, Aug-15, Volume: 200

    Topics: Animals; Animals, Newborn; Brain Stem; Cervical Vertebrae; Dose-Response Relationship, Drug; Female;

2014
Hypothalamic Paraventricular and Arcuate Nuclei Contribute to Elevated Sympathetic Nerve Activity in Pregnant Rats: Roles of Neuropeptide Y and α-Melanocyte-Stimulating Hormone.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 66, Issue:6

    Topics: alpha-MSH; Analysis of Variance; Animals; Arcuate Nucleus of Hypothalamus; Blood Pressure; Female; G

2015
Methylmercury-Dependent Increases in Fluo4 Fluorescence in Neonatal Rat Cerebellar Slices Depend on Granule Cell Migrational Stage and GABAA Receptor Modulation.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 356, Issue:1

    Topics: Aniline Compounds; Animals; Animals, Newborn; Bicuculline; Calcium Signaling; Cell Movement; Cell Su

2016
Increased GABAA receptor binding in amygdala after prenatal administration of valproic acid to rats.
    Acta neuropsychiatrica, 2017, Volume: 29, Issue:5

    Topics: Amygdala; Animals; Autism Spectrum Disorder; Autoradiography; Azides; Benzodiazepines; Carbon Radioi

2017
Inhibition of chloride outward transport by gadolinium in cultured rat spinal cord neurons.
    Neurotoxicology, 2009, Volume: 30, Issue:1

    Topics: Animals; Bumetanide; Cells, Cultured; Chlorides; Female; Furosemide; GABA-A Receptor Agonists; Gadol

2009
Modulation of GABAergic and glutamatergic transmission by ethanol in the developing neocortex: an in vitro test of the excessive inhibition hypothesis of fetal alcohol spectrum disorder.
    Neuropharmacology, 2009, Volume: 56, Issue:2

    Topics: Animals; Animals, Newborn; Biophysics; Calcium; Central Nervous System Depressants; Dizocilpine Male

2009
Excitatory and inhibitory neurotransmission is chronically altered following perinatal NMDA receptor blockade.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2009, Volume: 19, Issue:4

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Brain Mapping; Dizocilpine Maleate; Excitatory Amino

2009
KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner.
    Neuron, 2009, Apr-16, Volume: 62, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Chan

2009
Abnormal synaptic plasticity in basolateral amygdala may account for hyperactivity and attention-deficit in male rat exposed perinatally to low-dose bisphenol-A.
    Neuropharmacology, 2011, Volume: 60, Issue:5

    Topics: Air Pollutants, Occupational; Amygdala; Animals; Attention Deficit Disorder with Hyperactivity; Benz

2011
Autoradiographic analysis of GABAA receptor binding in the neural anxiety network of postpartum and non-postpartum laboratory rats.
    Brain research bulletin, 2011, Aug-10, Volume: 86, Issue:1-2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Autoradiography; Brain; Female; Flunitrazepam; GABA-A Recepto

2011
Muscimol delays lipopolysaccharide-induced preterm delivery in mice: role of GABA(A) receptors and nitric oxide.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:1

    Topics: Amniotic Fluid; Animals; Bicuculline; Disease Models, Animal; Female; GABA-A Receptor Agonists; GABA

2013
Maternal exposure to picrotoxin modifies the response of the GABAA receptor during sexual behavior of adult male rat offspring.
    Behavioural pharmacology, 2012, Volume: 23, Issue:7

    Topics: Animals; Female; GABA Antagonists; GABA-A Receptor Agonists; Injections, Subcutaneous; Lactation; Ma

2012
Receptor-activated calcium signals in tangentially migrating cortical cells.
    Cerebral cortex (New York, N.Y. : 1991), 2002, Volume: 12, Issue:8

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Calc

2002
Cross talk between the GABA(A) receptor and the Na-K-Cl cotransporter is mediated by intracellular Cl-.
    Journal of neurophysiology, 2003, Volume: 89, Issue:1

    Topics: Animals; Calcium; Cell Size; Cells, Cultured; Cerebral Cortex; Chlorides; Female; GABA Agonists; Mus

2003
Estradiol exacerbates hippocampal damage in a model of preterm infant brain injury.
    Endocrinology, 2003, Volume: 144, Issue:6

    Topics: Animals; Animals, Newborn; Cell Death; Cells, Cultured; Disease Models, Animal; Drug Synergism; Estr

2003
Spatial learning deficits induced by muscimol and CL218,872: lack of effect of prenatal malnutrition.
    Nutritional neuroscience, 2003, Volume: 6, Issue:6

    Topics: Animals; Body Weight; Female; GABA Agonists; GABA-A Receptor Agonists; Learning Disabilities; Motor

2003
Chronic stimulation of GABAA receptor with muscimol reduces amyloid beta protein (25-35)-induced neurotoxicity in cultured rat cortical cells.
    Neuroscience research, 2005, Volume: 52, Issue:4

    Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Baclofen; Blotting, Western; Calcium; Calcium

2005
Prolongation and enhancement of gamma-aminobutyric acid receptor mediated excitation by chronic treatment with estradiol in developing rat hippocampal neurons.
    The European journal of neuroscience, 2005, Volume: 21, Issue:12

    Topics: Animals; Bicuculline; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type

2005
Allosteric positive interaction of thymol with the GABAA receptor in primary cultures of mouse cortical neurons.
    Neuropharmacology, 2006, Volume: 50, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Chloride Channel

2006
Hyperthermia-induced seizures modify the GABAA and benzodiazepine receptor binding in immature rat brain.
    Cellular and molecular neurobiology, 2005, Volume: 25, Issue:6

    Topics: Animals; Animals, Newborn; Autoradiography; Brain; Child; Female; Fever; Flunitrazepam; GABA Agonist

2005
Sex- and cell-type-specific patterns of GABAA receptor and estradiol-mediated signaling in the immature rat substantia nigra.
    The European journal of neuroscience, 2006, Volume: 23, Issue:9

    Topics: Animals; Animals, Newborn; Cell Count; CREB-Binding Protein; Estradiol; Female; GABA Agonists; Immun

2006
Hyperthermia-induced seizures modify the GABA(A) and benzodiazepine receptor binding in immature rat brain.
    Cellular and molecular neurobiology, 2007, Volume: 27, Issue:2

    Topics: Age Factors; Animals; Autoradiography; Brain; Female; Fever; Flunitrazepam; GABA Agonists; GABA Modu

2007
Blockade of androgen receptors is sufficient to alter the sexual differentiation of the substantia nigra pars reticulata seizure-controlling network.
    Epileptic disorders : international epilepsy journal with videotape, 2008, Volume: 10, Issue:1

    Topics: Androgen Receptor Antagonists; Animals; Convulsants; Female; GABA Agonists; Male; Muscimol; Nerve Ne

2008
Regulation of prolactin secretion during suckling: involvement of the hypothalamo-pituitary GABAergic system.
    Journal of endocrinological investigation, 1984, Volume: 7, Issue:5

    Topics: Animals; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamo-Hypo

1984
Autoradiographic localization of binding sites for [3H]gamma-aminobutyrate, [3H]muscimol,(+)[3H]bicuculline methiodide and [3H] flunitrazepam in cultures of rat cerebellum and spinal cord.
    Neuroscience, 1980, Volume: 5, Issue:9

    Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Autoradiography; Bicuculline; Binding Sites; Cells,

1980
GABA and benzodiazepine receptors in the offspring of dams receiving diazepam: ontogenetic studies.
    Neuropharmacology, 1980, Volume: 19, Issue:10

    Topics: Animals; Behavior, Animal; Brain Chemistry; Diazepam; Female; Muscimol; Pregnancy; Rats; Receptors,

1980
Development of [3H]muscimol binding to subcellular particles of a culture of mouse brain.
    Neurochemical research, 1980, Volume: 5, Issue:12

    Topics: Animals; Axons; Brain; Cells, Cultured; Female; Mice; Microscopy, Phase-Contrast; Muscimol; Neurons;

1980
The insensitivity of developing benzodiazepine receptors to chronic treatment with diazepam, GABA and muscimol in brain cell cultures.
    Brain research, 1981, Apr-06, Volume: 210, Issue:1-2

    Topics: Animals; Brain; Cell Membrane; Cells, Cultured; Diazepam; Female; Fetus; gamma-Aminobutyric Acid; Ki

1981
Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study.
    Brain research, 1981, Volume: 254, Issue:4

    Topics: Aging; Animals; Autoradiography; Cerebellum; Clonazepam; Female; Flunitrazepam; gamma-Aminobutyric A

1981
Autoradiographic localization of binding sites for inhibitory amino acids and their antagonists in cultured rat CNS.
    Progress in brain research, 1983, Volume: 58

    Topics: Amino Acids; Animals; Animals, Newborn; Autoradiography; Bicuculline; Brain Stem; Cells, Cultured; C

1983
GABA-mediated inhibition of breathing in the late gestation sheep fetus.
    Journal of developmental physiology, 1983, Volume: 5, Issue:6

    Topics: Animals; Apnea; Female; Fetal Hypoxia; Fetus; gamma-Aminobutyric Acid; Gestational Age; Muscimol; Ox

1983
The ontogenesis of GABA mediated inhibition of growth hormone release in the sheep.
    Journal of developmental physiology, 1982, Volume: 4, Issue:4

    Topics: Animals; Animals, Newborn; Female; Fetus; gamma-Aminobutyric Acid; Growth Hormone; Muscimol; Picroto

1982
Biochemical development of the human brain. II. Some parameters of the GABA-ergic system.
    Developmental neuroscience, 1981, Volume: 4, Issue:3

    Topics: Adult; Aging; Cerebellum; Cerebral Cortex; DNA; Female; gamma-Aminobutyric Acid; Gestational Age; Gl

1981
Prenatal lorazepam exposure: 4. Persistent alterations in pentylenetetrazole-induced seizure threshold and GABA-dependent chloride uptake after prenatal lorazepam exposure.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 51, Issue:4

    Topics: Animals; Brain Chemistry; Chlorides; Chlorine; Female; gamma-Aminobutyric Acid; Lorazepam; Mice; Mus

1995
GABA inhibition of somatostatin gene expression in cultured hypothalamic neurones.
    Neuroreport, 1993, Volume: 4, Issue:3

    Topics: Actins; Animals; Bicuculline; Cell Survival; Cells, Cultured; DNA; DNA Probes; Female; gamma-Aminobu

1993
GABAergic cells and signals appear together in the early post-mitotic period of telencephalic and striatal development.
    Brain research. Developmental brain research, 1993, Jun-08, Volume: 73, Issue:2

    Topics: Acridine Orange; Animals; Corpus Striatum; Female; Flow Cytometry; Fluorescent Dyes; gamma-Aminobuty

1993
Molecular and functional adaptation of the GABA(A) receptor complex during pregnancy and after delivery in the rat brain.
    The European journal of neuroscience, 1998, Volume: 10, Issue:9

    Topics: Allosteric Regulation; Alternative Splicing; Animals; Brain Chemistry; Cerebral Cortex; Chlorides; D

1998
Persistent depolarizing action of GABA in rat Cajal-Retzius cells.
    The Journal of physiology, 1998, Nov-01, Volume: 512 ( Pt 3)

    Topics: Animals; Animals, Newborn; Calcium; Electrophysiology; Female; GABA Agonists; gamma-Aminobutyric Aci

1998
Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Oct-27, Volume: 95, Issue:22

    Topics: Animals; Cell Membrane; Cerebral Cortex; Chlorides; Desoxycorticosterone; Estrus; Female; Finasterid

1998
Influence of fetal alcohol exposure on the GABAergic regulation of growth hormone release in postnatal rats.
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:10

    Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Body Weight; Central Nervous System Depressants

1999
Effects of gamma-aminobutyric acid(A) receptor manipulation on migrating gonadotropin-releasing hormone neurons through the entire migratory route in vivo and in vitro.
    Endocrinology, 2000, Volume: 141, Issue:3

    Topics: Animals; Bicuculline; Cell Count; Cell Movement; Female; GABA Agonists; GABA Antagonists; GABA-A Rec

2000
[The mechanisms of the GABA-ergic regulation of beta-endorphin levels in the hypothalamic structures of prenatally stressed male rats].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2000, Volume: 46, Issue:2

    Topics: Animals; Baclofen; beta-Endorphin; Brain Chemistry; Female; GABA Agonists; Hypothalamus, Middle; Mal

2000
Luteinizing hormone-releasing hormone (LHRH) biosynthesis and secretion in embryonic LHRH.
    Endocrinology, 2000, Volume: 141, Issue:12

    Topics: Animals; Brain Chemistry; Calcium; Culture Techniques; Female; GABA Agonists; gamma-Aminobutyric Aci

2000
Prenatal AZT or 3TC and mouse development of locomotor activity and hot-plate responding upon administration of the GABA(A) receptor agonist muscimol.
    Psychopharmacology, 2001, Volume: 153, Issue:4

    Topics: Animals; Anti-HIV Agents; Female; GABA Agonists; GABA-A Receptor Agonists; Habituation, Psychophysio

2001
GABA promotes survival but not proliferation of parvalbumin-immunoreactive interneurons in rodent neostriatum: an in vivo study with stereology.
    Neuroscience, 2001, Volume: 104, Issue:1

    Topics: Animals; Animals, Newborn; Bicuculline; Cell Count; Cell Division; Cell Movement; Cell Survival; Emb

2001
Regulation of uterine gamma-aminobutyric acid(A) receptor subunit expression throughout pregnancy.
    Endocrinology, 2001, Volume: 142, Issue:5

    Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Animals; Female;

2001
Developmental exposure of rats to a reconstituted PCB mixture or aroclor 1254: effects on long-term potentiation and [3H]MK-801 binding in occipital cortex and hippocampus.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 61, Issue:2

    Topics: Administration, Oral; Analysis of Variance; Animals; Animals, Newborn; Binding Sites; Brain; Chlorod

2001
Chronic prenatal ethanol exposure increases GABA(A) receptor subunit protein expression in the adult guinea pig cerebral cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jun-15, Volume: 21, Issue:12

    Topics: Administration, Oral; Animals; Body Weight; Cerebral Cortex; Dizocilpine Maleate; Drug Administratio

2001
Activation of GABA(A) receptors in the accessory olfactory bulb does not prevent the formation of an olfactory memory in mice.
    The Journal of veterinary medical science, 2001, Volume: 63, Issue:7

    Topics: Animals; Female; GABA Agonists; Male; Memory; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Muscimol;

2001
The effect of GABA receptor ligands in experimental spina bifida occulta.
    BMC pharmacology, 2001, Volume: 1

    Topics: Animals; Baclofen; Bicuculline; Female; GABA Agonists; GABA Antagonists; Male; Muscimol; Pregnancy;

2001
3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex.
    Brain research. Developmental brain research, 2001, Nov-26, Volume: 131, Issue:1-2

    Topics: Allosteric Regulation; Animals; Animals, Newborn; Anti-Anxiety Agents; Biological Transport; Cerebra

2001
Nutritional parameters modify muricidal behavior of male Wistar rats: preventive effects of amino acids and 4' Cl diazepam.
    Life sciences, 2001, Oct-26, Volume: 69, Issue:23

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Benzodiazepinones; Cholesterol; Diet; Di

2001
Ontogeny of GABA and benzodiazepine receptors: effects of Triton X-100, bromide and muscimol.
    Brain research, 1979, Dec-28, Volume: 179, Issue:2

    Topics: Age Factors; Animals; Anti-Anxiety Agents; Bromides; Cerebellum; Female; Flunitrazepam; gamma-Aminob

1979
Evidence for a modulation of human chorionic gonadotropin (hCG) subunit messenger ribonucleic acid levels and hCG secretion by gamma-aminobutyric acid in human first trimester placenta in vitro.
    Endocrinology, 1992, Volume: 130, Issue:1

    Topics: Bicuculline; Chorionic Gonadotropin; Culture Techniques; Female; gamma-Aminobutyric Acid; Humans; Mu

1992
GABAergic influence on the development of the sexually dimorphic nucleus of male and female rats.
    Brain research, 1992, Feb-28, Volume: 573, Issue:2

    Topics: Animals; Female; gamma-Aminobutyric Acid; Hypothalamus; Luteinizing Hormone; Male; Muscimol; Neurons

1992
Prenatal exposure to benzodiazepine--I. Prenatal exposure to lorazepam in mice alters open-field activity and GABAA receptor function.
    Neuropharmacology, 1991, Volume: 30, Issue:1

    Topics: Animals; Brain; Cerebral Cortex; Chlorides; Female; Gestational Age; Lorazepam; Maternal-Fetal Excha

1991
Reduction of GABAA receptor-mediated inhibition by the non-NMDA receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione in cultured neurons of rat brain.
    Neuroscience letters, 1991, Jan-02, Volume: 121, Issue:1-2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Brain; Cadmium; Cells, Cultured; Embryo,

1991
Electrical and chemical excitability appear one week before birth in the embryonic rat spinal cord.
    Brain research, 1990, Jul-02, Volume: 522, Issue:1

    Topics: Animals; Electric Stimulation; Female; Fetus; Flow Cytometry; Fluorescence; gamma-Aminobutyric Acid;

1990
Action of baclofen, GABA and antagonists on the membrane potential of cultured astrocytes of rat spinal cord.
    Neuroscience letters, 1990, Sep-18, Volume: 117, Issue:3

    Topics: Animals; Astrocytes; Autoradiography; Baclofen; Bicuculline; Electrophysiology; Female; GABA Antagon

1990
Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors.
    Brain research, 1990, Jan-01, Volume: 506, Issue:1

    Topics: Aging; Animals; Brain; Female; Flunitrazepam; Male; Mice; Muscimol; Phenobarbital; Pregnancy; Prenat

1990
Central inhibition by gamma-aminobutyric acid and muscimol of the release of vasopressin and oxytocin by an osmotic stimulus in the rat.
    British journal of pharmacology, 1990, Volume: 99, Issue:3

    Topics: Animals; Diuresis; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Iodine Radioisotop

1990
Pregnancy-induced alterations of GABAA receptor sensitivity in maternal brain: an antecedent of post-partum 'blues'?
    Brain research, 1989, Mar-20, Volume: 482, Issue:2

    Topics: Animals; Female; Frontal Lobe; Gestational Age; Muscimol; Postpartum Period; Pregnancy; Pregnancy, A

1989
[The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1989, Issue:6

    Topics: Animals; Cerebral Cortex; Female; Muscimol; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rece

1989
Persistent alterations in GABAA receptor binding and function after prenatal lorazepam administration in the chick.
    Brain research bulletin, 1989, Volume: 23, Issue:3

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Chickens;

1989
Modulation of uterine GABAA receptors during gestation and by tetrahydroprogesterone.
    European journal of pharmacology, 1989, Dec-12, Volume: 174, Issue:1

    Topics: Animals; Female; Kinetics; Muscimol; Pregnancy; Pregnancy, Animal; Pregnanes; Pregnanolone; Rats; Ra

1989
Chronic phenytoin treatment decreases GABAA but not beta-adrenoceptors in the cerebellum of young rats.
    European journal of pharmacology, 1989, Sep-13, Volume: 168, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Cerebellum; Female; Flunitrazepam; Kinetics;

1989
The ontogeny of GABA receptors and glutamic acid decarboxylase in regions of the rat brain. Effect of prenatal exposure to diazepam.
    Neuropharmacology, 1988, Volume: 27, Issue:7

    Topics: Animals; Brain; Diazepam; Female; Glutamate Decarboxylase; Muscimol; Pregnancy; Prenatal Exposure De

1988
[Peculiarities of H3-muscimol binding to neocortex membranes of rats exposed to the effects of ethanol in the prenatal period].
    Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 106, Issue:10

    Topics: Age Factors; Animals; Cerebral Cortex; Ethanol; Female; Male; Muscimol; Pregnancy; Prenatal Exposure

1988
Postnatal development of transmitter systems: sexual differentiation of the GABAergic system and effects of muscimol.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1986, Volume: 4, Issue:4

    Topics: Aging; Animals; Brain; Female; gamma-Aminobutyric Acid; Male; Maternal-Fetal Exchange; Muscimol; Pre

1986