Page last updated: 2024-10-31

muscimol and Pain

muscimol has been researched along with Pain in 58 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"The present study evaluated the carvacrol (CARV) effect on hyperalgesia and nociception induced by sarcoma 180 (S180) in mice."7.80Evidence for the involvement of descending pain-inhibitory mechanisms in the attenuation of cancer pain by carvacrol aided through a docking study. ( Alves, RS; Bezerra, DP; De Lucca Júnior, W; Gelain, DP; Guimarães, AG; Melo, NS; Mendonça Júnior, FJ; Quintans Júnior, LJ; Scotti, L; Scotti, MT, 2014)
" Glycine or muscimol reduced bicuculline-induced allodynia regardless of the administration site, whereas intrathecal taurine reduced bicuculline-induced allodynia."7.76Intracisternal or intrathecal glycine, taurine, or muscimol inhibit bicuculline-induced allodynia and thermal hyperalgesia in mice. ( Lee, IO; Lim, ES, 2010)
"Muscimol doses were 0."5.28Ontogeny of muscimol effects on locomotor activity, habituation, and pain reactivity in mice. ( Alleva, E; Laviola, G, 1990)
"Microinjection of bicuculline and muscimol into the NC decreased and increased pain responses, respectively, in a dose-dependent manner during both phases of the test."4.02Effects of GABAA receptors in nucleus cuneiformis on the cannabinoid antinociception using the formalin test. ( Chen, J; Hasanein, P; Komaki, A; Yari, S, 2021)
"The present study evaluated the carvacrol (CARV) effect on hyperalgesia and nociception induced by sarcoma 180 (S180) in mice."3.80Evidence for the involvement of descending pain-inhibitory mechanisms in the attenuation of cancer pain by carvacrol aided through a docking study. ( Alves, RS; Bezerra, DP; De Lucca Júnior, W; Gelain, DP; Guimarães, AG; Melo, NS; Mendonça Júnior, FJ; Quintans Júnior, LJ; Scotti, L; Scotti, MT, 2014)
" Glycine or muscimol reduced bicuculline-induced allodynia regardless of the administration site, whereas intrathecal taurine reduced bicuculline-induced allodynia."3.76Intracisternal or intrathecal glycine, taurine, or muscimol inhibit bicuculline-induced allodynia and thermal hyperalgesia in mice. ( Lee, IO; Lim, ES, 2010)
"The GABAA agonist, muscimol, administered intrathecally (IT) to the spinal cord at a dose (1 microgram) that was subthreshold for affecting pain thresholds (vocalization-threshold-to-tail-shock: VTTS, and tail-flick latency: TFL) in ovariectomized, hormonally untreated rats, showed a significant increase in VTTS up to 30 min postinjection in intact females only in proestrus or estrus."3.68Modulation by estrogen and progesterone of the effect of muscimol on nociception in the spinal cord. ( Beyer, C; Caba, M; Komisaruk, BR; McCarthy, MM, 1990)
"Acute colitis was induced with 5 days of dextran sodium sulfate (DSS, 3%) in the drinking water."1.72Peripheral GABAA receptor signaling contributes to visceral hypersensitivity in a mouse model of colitis. ( Gold, MS; Loeza-Alcocer, E, 2022)
"Itch and pain are unpleasant sensations that distress many patients with disease."1.43GABA(A) Receptors in the Central Nucleus of the Amygdala Are Involved in Pain- and Itch-Related Responses. ( Chen, L; Dong, Z; Han, H; Tan, T; Wang, W, 2016)
"The muscimol effect was reverted by the chloride channel coupled GABA(A) receptor blocker, picrotoxin (0."1.34Involvement of GABA A receptor-associated chloride channels in the peripheral antinociceptive effect induced by GABA A receptor agonist muscimol. ( Castro, M; Duarte, I; Francischi, J; Pacheco, D; Perez, A; Reis, G, 2007)
"Laudanosine was almost ineffective at [3H]muscimol binding to high-affinity GABA receptors (IC50 = 100 microM)."1.29Interactions between laudanosine, GABA, and opioid subtype receptors: implication for laudanosine seizure activity. ( Fonia, O; Gavish, M; Katz, Y; Liu, L; Pasternak, GW; Pick, CG; Weizman, A, 1994)
"Muscimol doses were 0."1.28Ontogeny of muscimol effects on locomotor activity, habituation, and pain reactivity in mice. ( Alleva, E; Laviola, G, 1990)
"D-Baclofen is an antagonist at spinal baclofen receptors."1.27GABAergic mechanisms in antinociception. ( Sawynok, J, 1984)

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199010 (17.24)18.7374
1990's13 (22.41)18.2507
2000's20 (34.48)29.6817
2010's13 (22.41)24.3611
2020's2 (3.45)2.80

Authors

AuthorsStudies
Loeza-Alcocer, E1
Gold, MS1
Chen, J1
Hasanein, P2
Komaki, A1
Yari, S1
Shih, HC1
Kuan, YH1
Shyu, BC1
Zugaib, J2
Menescal-de-Oliveira, L3
Whitt, JL1
Masri, R1
Pulimood, NS1
Keller, A1
Coutinho, MR2
Ferreira, MD1
Jiang, ZC1
Pan, Q1
Zheng, C1
Deng, XF1
Wang, JY2
Luo, F2
Guimarães, AG1
Scotti, L1
Scotti, MT1
Mendonça Júnior, FJ1
Melo, NS1
Alves, RS1
De Lucca Júnior, W1
Bezerra, DP1
Gelain, DP1
Quintans Júnior, LJ1
Chen, L1
Wang, W1
Tan, T1
Han, H1
Dong, Z1
Roeder, Z1
Chen, Q1
Davis, S1
Carlson, JD1
Tupone, D1
Heinricher, MM1
Mirazi, N1
Javanmardi, K1
Wang, N1
Munn, EM1
Harte, SE1
Lagman, A1
Borszcz, GS2
Gau, R1
Sévoz-Couche, C1
Laguzzi, R1
Hamon, M1
Bernard, JF1
Coizet, V1
Dommett, EJ1
Klop, EM1
Redgrave, P2
Overton, PG1
da Silva, LF1
Viisanen, H1
Pertovaara, A1
Lee, IO1
Lim, ES1
Jhou, TC1
Xu, SP1
Lee, MR1
Gallen, CL1
Ikemoto, S1
Sumikura, H1
Arendt-Nielsen, L1
Manning, BH2
Martin, WJ1
Meng, ID1
Hough, LB1
Nalwalk, JW1
Svokos, K1
Leurs, R1
Timmermann, H1
Hara, K2
Saito, Y2
Kirihara, Y2
Sakura, S2
Jung, SC1
Kim, JH1
Choi, IS1
Cho, JH1
Bae, YC1
Lee, MG1
Shin, HC1
Choi, BJ1
Jiang, M1
Alheid, GF1
Calandriello, T1
McCrimmon, DR1
Göktalay, G1
Levendusky, MC1
Millington, WR1
Tang, J1
Ko, S1
Ding, HK1
Qiu, CS1
Calejesan, AA1
Zhuo, M1
Monconduit, L1
Lopez-Avila, A1
Molat, JL1
Chalus, M1
Villanueva, L1
Brink, TS1
Hellman, KM1
Lambert, AM1
Mason, P1
LaGraize, SC1
Fuchs, PN1
Reis, G1
Pacheco, D1
Francischi, J1
Castro, M1
Perez, A1
Duarte, I1
Sawynok, J1
Menon, MK1
Clark, WG1
Vivonia, C1
Mantegazza, P1
Tammiso, R1
Vicentini, L1
Zambotti, F1
Zonta, N1
Rahman, AF1
Takahashi, M1
Kaneto, H1
Lin, Q1
Peng, Y1
Willis, WD1
Katz, Y1
Weizman, A1
Pick, CG1
Pasternak, GW1
Liu, L1
Fonia, O1
Gavish, M1
Suh, HW1
Song, DK1
Son, KH1
Woo, MH1
Do, JC1
Choi, YS1
Lee, KH1
Kim, YH1
Archer, DP1
Ewen, A1
Froelich, J1
Roth, SH1
Samanani, N1
Cui, JG1
Linderoth, B1
Meyerson, BA1
Nguyen, TT1
Matsumoto, K1
Watanabe, H1
Wang, S1
Yamada, Y1
Kosaka, Y1
Hawkins, MF1
Baumeister, AA2
Larue, RH1
Fountain, LT1
Highsmith, RW1
Jeffries, SK1
Duke, MA1
Nalivaiko, E1
Blessing, WW1
Zarrindast, MR1
Mahmoudi, M1
Jasnow, AM1
Huhman, KL1
McCarthy, MM1
Caba, M1
Komisaruk, BR3
Beyer, C3
Laviola, G2
Alleva, E1
Banas, C1
Gonzalez-Flores, O1
Aley, KO1
Kulkarni, SK1
Frye, GD1
Roberts, LA1
Ye, WL1
Feng, XC1
Moreau, JL1
Fields, HL1

Other Studies

58 other studies available for muscimol and Pain

ArticleYear
Peripheral GABAA receptor signaling contributes to visceral hypersensitivity in a mouse model of colitis.
    Pain, 2022, 07-01, Volume: 163, Issue:7

    Topics: Animals; Bicuculline; Colitis; Colon; Dextran Sulfate; Diazepam; Disease Models, Animal; Inflammator

2022
Effects of GABAA receptors in nucleus cuneiformis on the cannabinoid antinociception using the formalin test.
    Psychopharmacology, 2021, Volume: 238, Issue:6

    Topics: Animals; Benzoxazines; Bicuculline; Cannabinoids; GABA-A Receptor Agonists; GABA-A Receptor Antagoni

2021
Targeting brain-derived neurotrophic factor in the medial thalamus for the treatment of central poststroke pain in a rodent model.
    Pain, 2017, Volume: 158, Issue:7

    Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; GABA-A Receptor Agonists; Male;

2017
Cholinergic/opioid interaction in anterior cingulate cortex reduces the nociceptive response of vocalization in guinea pigs.
    Brain research, 2017, Sep-15, Volume: 1671

    Topics: Acetylcholine; Analgesics, Opioid; Animals; Atropine; Carbachol; Cholinergic Agents; Guinea Pigs; Gy

2017
Pathological activity in mediodorsal thalamus of rats with spinal cord injury pain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Feb-27, Volume: 33, Issue:9

    Topics: Action Potentials; Afferent Pathways; Animals; Disease Models, Animal; Functional Laterality; GABA-A

2013
Glutamate/GABA balance in ACC modulates the nociceptive responses of vocalization: an expression of affective-motivational component of pain in guinea pigs.
    Physiology & behavior, 2014, Mar-14, Volume: 126

    Topics: Animals; Bicuculline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid A

2014
Inactivation of the prelimbic rather than infralimbic cortex impairs acquisition and expression of formalin-induced conditioned place avoidance.
    Neuroscience letters, 2014, May-21, Volume: 569

    Topics: Animals; Avoidance Learning; Conditioning, Classical; Formaldehyde; GABA-A Receptor Agonists; Male;

2014
Evidence for the involvement of descending pain-inhibitory mechanisms in the attenuation of cancer pain by carvacrol aided through a docking study.
    Life sciences, 2014, Oct-22, Volume: 116, Issue:1

    Topics: Analgesics; Animals; Cymenes; Dose-Response Relationship, Drug; Hyperalgesia; Interleukin-10; Male;

2014
GABA(A) Receptors in the Central Nucleus of the Amygdala Are Involved in Pain- and Itch-Related Responses.
    The journal of pain, 2016, Volume: 17, Issue:2

    Topics: Animals; Behavior, Animal; Bicuculline; Central Amygdaloid Nucleus; Disease Models, Animal; GABA-A R

2016
Parabrachial complex links pain transmission to descending pain modulation.
    Pain, 2016, Volume: 157, Issue:12

    Topics: Action Potentials; Anesthetics, Local; Animals; Calcitonin Gene-Related Peptide; GABA-A Receptor Ago

2016
GABAA receptors in the central nucleus of amygdala (CeA) affect on pain modulation.
    Brain research, 2008, Nov-19, Volume: 1241

    Topics: Amygdala; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; G

2008
Corticofugal outputs facilitate acute, but inhibit chronic pain in rats.
    Pain, 2009, Volume: 142, Issue:1-2

    Topics: Analysis of Variance; Animals; Bicuculline; Chronic Disease; Disease Models, Animal; Freund's Adjuva

2009
Contribution of the periaqueductal gray to the suppression of pain affect produced by administration of morphine into the intralaminar thalamus of rat.
    The journal of pain, 2009, Volume: 10, Issue:4

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Electroshock; GABA Agonists; Intralaminar Thalamic Nu

2009
Inhibition of cardiac baroreflex by noxious thermal stimuli: a key role for lateral paragigantocellular serotonergic cells.
    Pain, 2009, Volume: 146, Issue:3

    Topics: Animals; Baroreflex; Fluorescent Dyes; GABA Agonists; Genes, fos; Granisetron; Heart; Hot Temperatur

2009
The parabrachial nucleus is a critical link in the transmission of short latency nociceptive information to midbrain dopaminergic neurons.
    Neuroscience, 2010, Jun-16, Volume: 168, Issue:1

    Topics: Anesthetics, Local; Animals; Dopamine; Electric Stimulation; Electrophysiology; Female; GABA-A Recep

2010
Opioidergic and GABAergic mechanisms in the rostral ventromedial medulla modulate the nociceptive response of vocalization in guinea pigs.
    Brain research bulletin, 2010, May-31, Volume: 82, Issue:3-4

    Topics: Analgesics, Opioid; Animals; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid;

2010
Roles of the rostroventromedial medulla and the spinal 5-HT(1A) receptor in descending antinociception induced by motor cortex stimulation in the neuropathic rat.
    Neuroscience letters, 2010, Jun-07, Volume: 476, Issue:3

    Topics: Animals; Electric Stimulation Therapy; GABA-A Receptor Agonists; Male; Medulla Oblongata; Motor Cort

2010
Intracisternal or intrathecal glycine, taurine, or muscimol inhibit bicuculline-induced allodynia and thermal hyperalgesia in mice.
    Acta pharmacologica Sinica, 2010, Volume: 31, Issue:8

    Topics: Animals; Bicuculline; Disease Models, Animal; Glycine; Hot Temperature; Hyperalgesia; Injections; In

2010
Mapping of reinforcing and analgesic effects of the mu opioid agonist endomorphin-1 in the ventral midbrain of the rat.
    Psychopharmacology, 2012, Volume: 224, Issue:2

    Topics: Analgesics, Opioid; Animals; Dopamine; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; M

2012
MAC reduction after intrathecal coadministration of GABA(A) agonist and glutamate antagonist in rats.
    Journal of anesthesia, 2003, Volume: 17, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Inhalation; Animals; Drug Synergism; Excitatory Amino Acid

2003
The rodent amygdala contributes to the production of cannabinoid-induced antinociception.
    Neuroscience, 2003, Volume: 120, Issue:4

    Topics: Amygdala; Analgesics; Animals; Benzoxazines; Cannabinoids; Cell Count; Dose-Response Relationship, D

2003
Pain-relieving drugs and the brain histaminergic system: multiple analgesic mechanisms from histamine, improgan and cimetidine.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53 Suppl 1

    Topics: Analgesics; Animals; Cimetidine; Male; Muscimol; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley

2004
The interaction between gamma-aminobutyric acid agonists and diltiazem in visceral antinociception in rats.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:5

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Catheterization; Colon; Diltiazem; Drug

2004
Corticothalamic modulation on formalin-induced change of VPM thalamic activities.
    Neuroreport, 2004, Jun-28, Volume: 15, Issue:9

    Topics: Animals; Bicuculline; Formaldehyde; GABA Agonists; GABA Antagonists; Male; Muscimol; Neural Pathways

2004
Parabrachial-lateral pontine neurons link nociception and breathing.
    Respiratory physiology & neurobiology, 2004, Nov-15, Volume: 143, Issue:2-3

    Topics: Action Potentials; Animals; Brain Mapping; Drug Administration Schedule; Extremities; Fluorescent Dy

2004
Muscimol injection into the lateral hypothalamus inhibits the hypotension and bradycardia caused by somato-visceral nociception.
    Brain research, 2004, Dec-10, Volume: 1029, Issue:1

    Topics: Animals; Bradycardia; Cardiovascular Physiological Phenomena; GABA Agonists; Homocysteine; Hypotensi

2004
Pavlovian fear memory induced by activation in the anterior cingulate cortex.
    Molecular pain, 2005, Feb-09, Volume: 1

    Topics: Animals; Fear; GABA-A Receptor Agonists; Gyrus Cinguli; Humans; Male; Memory; Mice; Mice, Inbred C57

2005
Contribution of the ventromedial hypothalamus to generation of the affective dimension of pain.
    Pain, 2006, Volume: 123, Issue:1-2

    Topics: Affect; Animals; Bicuculline; Conditioning, Classical; Electric Stimulation; Electroshock; Fear; GAB

2006
Corticofugal output from the primary somatosensory cortex selectively modulates innocuous and noxious inputs in the rat spinothalamic system.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Aug-16, Volume: 26, Issue:33

    Topics: Animals; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Hindlimb; Homocy

2006
Raphe magnus neurons help protect reactions to visceral pain from interruption by cutaneous pain.
    Journal of neurophysiology, 2006, Volume: 96, Issue:6

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Catheterization; Electric Stimulation; Electrophysiol

2006
GABAA but not GABAB receptors in the rostral anterior cingulate cortex selectively modulate pain-induced escape/avoidance behavior.
    Experimental neurology, 2007, Volume: 204, Issue:1

    Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Escape Reaction; GABA Agonists; GABA Antagonists

2007
Involvement of GABA A receptor-associated chloride channels in the peripheral antinociceptive effect induced by GABA A receptor agonist muscimol.
    European journal of pharmacology, 2007, Jun-14, Volume: 564, Issue:1-3

    Topics: Analysis of Variance; Animals; Bicuculline; Chloride Channels; Dinoprostone; Dose-Response Relations

2007
GABAergic mechanisms in antinociception.
    Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:4-6

    Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Analgesics; Animals; Baclofen; Bicuculline; Central Ne

1984
Interaction between phencyclidine (PCP) and GABA-ergic drugs: clinical implications.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:1

    Topics: Aminooxyacetic Acid; Anesthesia; Animals; Baclofen; Dextroamphetamine; Diazepam; Drug Interactions;

1980
The effect of GABAergic agents on opiate analgesia.
    Pharmacological research communications, 1980, Volume: 12, Issue:3

    Topics: Animals; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Injections, Intraventricular; Isoni

1980
Role of GABAergic systems in the development of morphine tolerance in formalin-treated mice.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:2

    Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Diazepam; Drug Tolerance; Flumazenil; Formaldehy

1995
Glycine and GABAA antagonists reduce the inhibition of primate spinothalamic tract neurons produced by stimulation in periaqueductal gray.
    Brain research, 1994, Aug-22, Volume: 654, Issue:2

    Topics: Animals; Bicuculline; Brain Mapping; Dose-Response Relationship, Drug; Electric Stimulation; GABA-A

1994
Interactions between laudanosine, GABA, and opioid subtype receptors: implication for laudanosine seizure activity.
    Brain research, 1994, May-23, Volume: 646, Issue:2

    Topics: Animals; Bicuculline; Binding, Competitive; Brain; Cell Membrane; Cerebral Ventricles; GABA Antagoni

1994
Antinociceptive effect of smilaxin B administered intracerebroventricularly in the mouse.
    Planta medica, 1996, Volume: 62, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Cerebral Ventricles; Dizocilpine Maleate; G

1996
Thiopentone induced enhancement of somatic motor responses to noxious stimulation: influence of GABAA receptor modulation.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:5 Pt 1

    Topics: Animals; Bicuculline; GABA Modulators; Hypnotics and Sedatives; Male; Muscimol; Pain; Rats; Rats, Sp

1996
Effects of spinal cord stimulation on touch-evoked allodynia involve GABAergic mechanisms. An experimental study in the mononeuropathic rat.
    Pain, 1996, Volume: 66, Issue:2-3

    Topics: Animals; Baclofen; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists;

1996
Involvement of supraspinal GABA-ergic systems in clonidine-induced antinociception in the tail-pinch test in mice.
    Life sciences, 1997, Volume: 61, Issue:11

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Baclofen; Bicuculline; Clonidine; GABA An

1997
Microinjections of muscimol into lateral superior colliculus disrupt orienting and oral movements in the formalin model of pain.
    Neuroscience, 1997, Volume: 81, Issue:4

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Functional Latera

1997
A lateralized deficit in morphine antinociception after unilateral inactivation of the central amygdala.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Nov-15, Volume: 18, Issue:22

    Topics: Afferent Pathways; Amygdala; Animals; Behavior, Animal; Disinfectants; Dose-Response Relationship, D

1998
The interaction of antinociceptive effects of morphine and GABA receptor agonists within the rat spinal cord.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:2

    Topics: Analgesics, Opioid; Animals; Baclofen; Colon; Dose-Response Relationship, Drug; Drug Interactions; D

1999
Central GABA activation and behaviors evoked by tail-pinch stress in the rat.
    Physiology & behavior, 1999, Volume: 67, Issue:5

    Topics: Animals; Behavior, Animal; Defecation; GABA Agonists; gamma-Aminobutyric Acid; Injections, Intravent

1999
Raphe region mediates changes in cutaneous vascular tone elicited by stimulation of amygdala and hypothalamus in rabbits.
    Brain research, 2001, Feb-09, Volume: 891, Issue:1-2

    Topics: Amygdala; Animals; Electric Stimulation; GABA Agonists; Hypothalamus; Male; Medulla Oblongata; Musci

2001
GABA mechanisms and antinociception in mice with ligated sciatic nerve.
    Pharmacology & toxicology, 2001, Volume: 89, Issue:2

    Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists;

2001
Activation of GABA(A) receptors in the amygdala blocks the acquisition and expression of conditioned defeat in Syrian hamsters.
    Brain research, 2001, Nov-30, Volume: 920, Issue:1-2

    Topics: Amygdala; Animals; Conditioning, Psychological; Cricetinae; Dose-Response Relationship, Drug; GABA A

2001
Modulation by estrogen and progesterone of the effect of muscimol on nociception in the spinal cord.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:1

    Topics: Animals; Estradiol; Estrogens; Estrus; Female; Injections, Spinal; Muscimol; Ovary; Pain; Progestero

1990
Ontogeny of muscimol effects on locomotor activity, habituation, and pain reactivity in mice.
    Psychopharmacology, 1990, Volume: 102, Issue:1

    Topics: Aging; Animals; Brain Chemistry; Female; Habituation, Psychophysiologic; Male; Mice; Motor Activity;

1990
Blockage of substance P-induced scratching behavior in rats by the intrathecal administration of inhibitory amino acid agonists.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:3

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Glycine; Injections, Spinal; Mu

1989
GABAergic agents-induced antinociceptive effect in mice.
    Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:10

    Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Mice; Morphine; M

1989
Involvement of the midbrain reticular formation in self-injurious behavior, stereotyped behavior, and analgesia induced by intranigral microinjection of muscimol.
    Brain research, 1986, Mar-26, Volume: 369, Issue:1-2

    Topics: Animals; Brain Mapping; gamma-Aminobutyric Acid; Male; Mesencephalon; Muscimol; Pain; Rats; Rats, In

1986
Nociceptive responses to altered GABAergic activity at the spinal cord.
    Life sciences, 1986, Nov-03, Volume: 39, Issue:18

    Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Injections, Spinal; Motor Activity; Muscimol;

1986
[Ontogeny of GABAergic modulation on locomotor activity and pain reactivity in mice].
    Annali dell'Istituto superiore di sanita, 1988, Volume: 24, Issue:4

    Topics: Animals; Brain; Drug Tolerance; Female; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Muscimo

1988
[Potentiation of acupuncture analgesia by GABA in the dorsal raphe nucleus].
    Sheng li xue bao : [Acta physiologica Sinica], 1986, Volume: 38, Issue:2

    Topics: 3-Mercaptopropionic Acid; Acupuncture Therapy; Animals; Bicuculline; Electric Stimulation Therapy; g

1986
Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission.
    Brain research, 1986, Nov-05, Volume: 397, Issue:1

    Topics: Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Morphine;

1986