muscimol has been researched along with Nervous System Disorders in 2 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of N-(2,6-dimethyl-phenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (DM-9384), a cyclic derivative of GABA, were investigated and compared with those of aniracetam in an animal model of amnesia, using a passive avoidance task with animals that have GABAergic neuronal dysfunctions." | 3.68 | Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions. ( Itoh, J; Kameyama, T; Nabeshima, T; Noda, Y; Tohyama, K, 1990) |
| "The onset of tremors and convulsions, which occur as pressure is increased, were used as endpoints for assessing the onset and severity of the HPNS." | 1.27 | Interactions of gamma-aminobutyric acid and noradrenaline in the high pressure neurological syndrome. ( Angel, A; Halsey, MJ; Wardley-Smith, B, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Angel, A | 1 |
| Halsey, MJ | 1 |
| Wardley-Smith, B | 1 |
| Nabeshima, T | 1 |
| Noda, Y | 1 |
| Tohyama, K | 1 |
| Itoh, J | 1 |
| Kameyama, T | 1 |
2 other studies available for muscimol and Nervous System Disorders
| Article | Year |
|---|---|
Interactions of gamma-aminobutyric acid and noradrenaline in the high pressure neurological syndrome.
Topics: Aminobutyrates; Animals; Brain; Drug Interactions; Female; Hydroxydopamines; Injections, Intraventri | 1983 |
Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions.
Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Central Nervous System Agents; gamma-Aminobutyric | 1990 |