muscimol has been researched along with Myoclonic Jerk in 11 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In male Swiss mice, muscimol produced myoclonic jerks." | 7.66 | Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice. ( Menon, MK; Vivonia, CA, 1981) |
| "A number of clinically used benzodiazepines were tested for their effectiveness in blocking muscimol-induced myoclonic jerks in mice." | 7.66 | A new method for the evaluation of benzodiazepines based on their ability to block muscimol-induced myoclonic jerks in mice. ( Haddox, VG; Menon, MK; Vivonia, CA, 1981) |
| "In male Swiss mice, muscimol produced myoclonic jerks." | 3.66 | Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice. ( Menon, MK; Vivonia, CA, 1981) |
| "A number of clinically used benzodiazepines were tested for their effectiveness in blocking muscimol-induced myoclonic jerks in mice." | 3.66 | A new method for the evaluation of benzodiazepines based on their ability to block muscimol-induced myoclonic jerks in mice. ( Haddox, VG; Menon, MK; Vivonia, CA, 1981) |
| "In Swiss mice, muscimol (3 mg per kilogram, intraperitoneally) caused myoclonic jerks of the hindquarters." | 3.66 | Gamma-hydroxybutyrate in experimental myoclonus. ( Menon, MK, 1982) |
| "Inherited congenital myoclonus (ICM) of Poll Hereford cattle is a neurological disease in which there are severe alterations in spinal cord glycine-mediated neurotransmission." | 1.28 | Increased gamma-aminobutyric acid receptor function in the cerebral cortex of myoclonic calves with an hereditary deficit in glycine/strychnine receptors. ( Dodd, PR; Gundlach, AL; Harper, PA; Johnston, GA; Lummis, SC, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Menon, MK | 5 |
| Vivonia, CA | 2 |
| File, SE | 1 |
| Simmonds, MA | 1 |
| Haddox, VG | 1 |
| Kriem, B | 1 |
| Cagniard, B | 1 |
| Bouquet, C | 1 |
| Rostain, JC | 1 |
| Abraini, JH | 1 |
| Lummis, SC | 1 |
| Gundlach, AL | 1 |
| Johnston, GA | 1 |
| Harper, PA | 1 |
| Dodd, PR | 1 |
| Meldrum, BS | 1 |
| Pranzatelli, MR | 1 |
| Snodgrass, SR | 1 |
| Chapman, AG | 1 |
3 reviews available for muscimol and Myoclonic Jerk
| Article | Year |
|---|---|
Drugs acting on amino acid neurotransmitters.
Topics: Acoustic Stimulation; Amino Acids; Animals; Chemical Phenomena; Chemistry; Diazepam; Electrophysiolo | 1986 |
The pharmacology of myoclonus.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzodiazepines; Brain; | 1985 |
Valproate and myoclonus.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; F | 1986 |
8 other studies available for muscimol and Myoclonic Jerk
| Article | Year |
|---|---|
Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Male; Mice; Muscimol; | 1981 |
Interactions of two phenylquinolines with picrotoxin and benzodiazepines in vivo and in vitro.
Topics: Animals; Anticonvulsants; Benzodiazepines; Drug Interactions; gamma-Aminobutyric Acid; Male; Mice; M | 1984 |
A new method for the evaluation of benzodiazepines based on their ability to block muscimol-induced myoclonic jerks in mice.
Topics: Animals; Benzodiazepines; Diazepam; Drug Evaluation; Flunitrazepam; Male; Mice; Muscimol; Myoclonus; | 1981 |
Gamma-hydroxybutyrate in experimental myoclonus.
Topics: Animals; Hydroxybutyrates; Male; Mice; Muscimol; Myoclonus; Sodium Oxybate | 1982 |
Demonstration of the antimyoclonic effect of 1-hydroxy-3-amino-pyrrolidone-2 (HA-966) using a new animal model.
Topics: Animals; Anticonvulsants; Male; Mice; Muscimol; Myoclonus; Pyrrolidinones | 1981 |
Paradoxical blockade of a muscimol response by THIP, a GABA agonist and also by GABA-transaminase inhibitors.
Topics: 4-Aminobutyrate Transaminase; Animals; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Muscimol; My | 1981 |
Modulation by GABA transmission in the substantia nigra compacta and reticulata of locomotor activity in rats exposed to high pressure.
Topics: Animals; Baclofen; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Helium | 1998 |
Increased gamma-aminobutyric acid receptor function in the cerebral cortex of myoclonic calves with an hereditary deficit in glycine/strychnine receptors.
Topics: Animals; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle | 1990 |