muscimol has been researched along with Muscle Spasticity in 2 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Excerpt | Relevance | Reference |
|---|---|---|
| "835 and a parallel shift of the probit-log dosage regression line to the right." | 1.27 | Delta-aminovaleric acid antagonizes the pharmacological actions of baclofen in the central nervous system. ( Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Wüllner, U, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Turski, L | 2 |
| Klockgether, T | 2 |
| Turski, WA | 1 |
| Schwartz, M | 1 |
| Sontag, KH | 2 |
| Schwarz, M | 1 |
| Wüllner, U | 1 |
2 other studies available for muscimol and Muscle Spasticity
| Article | Year |
|---|---|
The entopeduncular nucleus regulates muscle tone in genetically spastic rats: role of substance P and gamma-aminobutyric acid.
Topics: Animals; Female; gamma-Aminobutyric Acid; Globus Pallidus; Male; Muscimol; Muscle Spasticity; Muscle | 1990 |
Delta-aminovaleric acid antagonizes the pharmacological actions of baclofen in the central nervous system.
Topics: Animals; Baclofen; Bicuculline; Drug Antagonism; Electric Stimulation; Female; gamma-Aminobutyric Ac | 1988 |