muscimol has been researched along with Muscle Rigidity in 6 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The haloperidol catalepsy was strongly inhibited by administration of picrotoxin to the Vm while the morphine catalepsy remained unchanged after picrotoxin." | 1.27 | Thalamus as a relay station for catalepsy and rigidity. ( Kolasiewicz, W; Ossowska, K; Wolfarth, S, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ellenbroek, B | 1 |
| Schwarz, M | 2 |
| Sontag, KH | 2 |
| Cools, A | 1 |
| Turski, L | 2 |
| Havemann, U | 1 |
| Kuschinsky, K | 1 |
| Wichmann, T | 1 |
| Bergman, H | 1 |
| DeLong, MR | 1 |
| van den Bos, R | 1 |
| Cools, AR | 1 |
| Wolfarth, S | 2 |
| Kolasiewicz, W | 1 |
| Ossowska, K | 1 |
| Klockgether, T | 1 |
6 other studies available for muscimol and Muscle Rigidity
| Article | Year |
|---|---|
The role of the colliculus superior in the expression of muscular rigidity.
Topics: Animals; Bicuculline; Electromyography; Male; Muscimol; Muscle Rigidity; Rats; Rats, Inbred Strains; | 1984 |
GABAergic mechanisms in mediating muscular rigidity, catalepsy and postural asymmetry in rats: differences between dorsal and ventral striatum.
Topics: Animals; Catalepsy; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Muscle Rigidit | 1984 |
The primate subthalamic nucleus. III. Changes in motor behavior and neuronal activity in the internal pallidum induced by subthalamic inactivation in the MPTP model of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Afferent Pathways; Animals; Bicuculline; Brain Mapping | 1994 |
Involvement of the substantia innominata/ventral pallidum complex in transmitting forelimb muscular rigidity evoked from the nucleus accumbens in rats.
Topics: Animals; Basal Ganglia; Bicuculline; Electrodes; Electromyography; Forelimb; Haloperidol; Injections | 1989 |
Thalamus as a relay station for catalepsy and rigidity.
Topics: Animals; Brain Mapping; Catalepsy; Escape Reaction; Haloperidol; Male; Morphine; Muscimol; Muscle Ri | 1985 |
Rigidity and catalepsy after injections of muscimol into the ventromedial thalamic nucleus: an electromyographic study in the rat.
Topics: Animals; Bicuculline; Catalepsy; Electromyography; Humans; Male; Muscimol; Muscle Rigidity; Oxazoles | 1985 |