muscimol has been researched along with Movement Disorders in 11 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishida, A | 1 |
| Isa, K | 1 |
| Umeda, T | 1 |
| Kobayashi, K | 2 |
| Hida, H | 1 |
| Isa, T | 1 |
| Sindhurakar, A | 1 |
| Butensky, SD | 1 |
| Meyers, E | 1 |
| Santos, J | 1 |
| Bethea, T | 1 |
| Khalili, A | 1 |
| Sloan, AP | 1 |
| Rennaker, RL | 1 |
| Carmel, JB | 1 |
| Karachi, C | 1 |
| Grabli, D | 1 |
| Baup, N | 1 |
| Mounayar, S | 1 |
| Tandé, D | 1 |
| François, C | 1 |
| Hirsch, EC | 1 |
| Creed, MC | 1 |
| Hamani, C | 1 |
| Nobrega, JN | 1 |
| Marsden, CD | 1 |
| Sheehy, MP | 1 |
| Crossman, AR | 1 |
| Sambrook, MA | 1 |
| Jackson, A | 1 |
| Burbaud, P | 1 |
| Bonnet, B | 1 |
| Guehl, D | 1 |
| Lagueny, A | 1 |
| Bioulac, B | 1 |
| Fogassi, L | 1 |
| Gallese, V | 1 |
| Buccino, G | 1 |
| Craighero, L | 1 |
| Fadiga, L | 1 |
| Rizzolatti, G | 1 |
| Di Chiara, G | 1 |
| Morelli, M | 1 |
| Porceddu, ML | 1 |
| Gessa, GL | 1 |
| Spooren, WP | 1 |
| Groenewegen, HJ | 1 |
| Cools, AR | 1 |
| Scheel-Krüger, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Subthalamic Nucleus Deep Brain Stimulation in Tourette's Syndrome[NCT02619084] | Phase 2 | 10 participants (Actual) | Interventional | 2011-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for muscimol and Movement Disorders
| Article | Year |
|---|---|
GABA and movement disorders.
Topics: Anticonvulsants; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; | 1981 |
10 other studies available for muscimol and Movement Disorders
| Article | Year |
|---|---|
Causal Link between the Cortico-Rubral Pathway and Functional Recovery through Forced Impaired Limb Use in Rats with Stroke.
Topics: Animals; Biotin; Cerebral Hemorrhage; Deep Brain Stimulation; Dextrans; Disease Models, Animal; Doxy | 2016 |
An Automated Test of Rat Forelimb Supination Quantifies Motor Function Loss and Recovery After Corticospinal Injury.
Topics: Animals; Automation, Laboratory; Disease Models, Animal; Equipment Design; Female; Food; Forelimb; M | 2017 |
Dysfunction of the subthalamic nucleus induces behavioral and movement disorders in monkeys.
Topics: Animals; Behavior, Animal; Bicuculline; Chlorocebus aethiops; Disease Models, Animal; Functional Lat | 2009 |
Early gene mapping after deep brain stimulation in a rat model of tardive dyskinesia: comparison with transient local inactivation.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Deep Brain Stimulation; Early Growth Response P | 2012 |
Experimental hemichorea/hemiballismus in the monkey. Studies on the intracerebral site of action in a drug-induced dyskinesia.
Topics: Animals; Bicuculline; Brain Diseases; Brain Mapping; Chorea; Dyskinesia, Drug-Induced; Female; Globu | 1984 |
Movement disorders induced by gamma-aminobutyric agonist and antagonist injections into the internal globus pallidus and substantia nigra pars reticulata of the monkey.
Topics: Animals; Bicuculline; GABA Agonists; GABA Antagonists; Globus Pallidus; Injections; Macaca fascicula | 1998 |
Cortical mechanism for the visual guidance of hand grasping movements in the monkey: A reversible inactivation study.
Topics: Animals; Functional Laterality; GABA Agonists; Hand; Hand Strength; Macaca nemestrina; Motor Cortex; | 2001 |
Role of thalamic gamma-aminobutyrate in motor functions: catalepsy and ipsiversive turning after intrathalamic muscimol.
Topics: Animals; Brain Mapping; Catalepsy; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Male; Motor Act | 1979 |
Subregions of the caudate nucleus and their in- and output channels in oro-facial dyskinesia: a behavioural and retrograde tracing study in the cat.
Topics: Animals; Axonal Transport; Carbachol; Catecholamines; Cats; Caudate Nucleus; Dopamine Agents; Facial | 1991 |
Dopamine-GABA interactions: evidence that GABA transmits, modulates and mediates dopaminergic functions in the basal ganglia and the limbic system.
Topics: Amygdala; Animals; Basal Ganglia; Behavior, Animal; Benzodiazepines; Catalepsy; Corpus Striatum; Dop | 1986 |