muscimol has been researched along with Memory Disorders in 20 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bicuculline treatment significantly reduced demyelination extension and increased the level of MBP expression." | 1.48 | Inhibition of GABA A receptor improved spatial memory impairment in the local model of demyelination in rat hippocampus. ( Afghani, A; Ashrafpour, M; Ashrafpour, S; Dehghan, S; Ebrahim Tabar, F; Gol, M; Mousavi Majd, A; Pourabdolhossein, F, 2018) |
| "Muscimol pretreatment did not change D-AP5-induced anxiolytic-like behaviors but potentiated avoidance memory impairment." | 1.43 | The role of CA3 GABAA receptors on anxiolytic-like behaviors and avoidance memory deficit induced by NMDA receptor antagonists. ( Farahizadeh, M; Nasehi, M; Zarrabian, S; Zarrindast, MR, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oh, JP | 1 |
| Han, JH | 1 |
| Nasehi, M | 3 |
| Roghani, F | 1 |
| Ebrahimi-Ghiri, M | 1 |
| Zarrindast, MR | 4 |
| Mousavi Majd, A | 1 |
| Ebrahim Tabar, F | 1 |
| Afghani, A | 1 |
| Ashrafpour, S | 1 |
| Dehghan, S | 1 |
| Gol, M | 1 |
| Ashrafpour, M | 1 |
| Pourabdolhossein, F | 1 |
| Jafari-Sabet, M | 1 |
| Banafshe, HR | 1 |
| Khodadadnejad, MA | 1 |
| Sardari, M | 1 |
| Rezayof, A | 1 |
| Khodagholi, F | 1 |
| Hasanein, P | 1 |
| Sharifi, M | 1 |
| Kim, J | 1 |
| Wasserman, EA | 1 |
| Castro, L | 1 |
| Freeman, JH | 1 |
| Zarrabian, S | 1 |
| Farahizadeh, M | 1 |
| Khakpoor, M | 1 |
| Vahdati, A | 1 |
| Hoseyni, SE | 1 |
| Stackman, RW | 1 |
| Cohen, SJ | 1 |
| Lora, JC | 1 |
| Rios, LM | 1 |
| Frauenknecht, K | 1 |
| Plaschke, K | 1 |
| Sommer, C | 1 |
| Jo, YS | 1 |
| Lee, I | 1 |
| Shah, AA | 1 |
| Parent, MB | 4 |
| Kim, JJ | 1 |
| Koo, JW | 1 |
| Lee, HJ | 1 |
| Han, JS | 1 |
| Krebs, DL | 1 |
| Amaral, OB | 1 |
| Luft, T | 1 |
| Cammarota, M | 1 |
| Izquierdo, I | 2 |
| Roesler, R | 1 |
| Yamamoto, Y | 1 |
| Mikami, A | 1 |
| Fujii, Y | 1 |
| Kamei, C | 1 |
| Krebs-Kraft, DL | 2 |
| Wheeler, MG | 1 |
| Spanis, CW | 1 |
| Bianchin, MM | 1 |
| McGaugh, JL | 1 |
20 other studies available for muscimol and Memory Disorders
| Article | Year |
|---|---|
A critical role of hippocampus for formation of remote cued fear memory.
Topics: Acoustic Stimulation; Animals; Conditioning, Classical; Cues; Fear; Hippocampus; Male; Memory Disord | 2020 |
Role of the amygdala GABA-A receptors in ACPA-induced deficits during conditioned fear learning.
Topics: Amygdala; Animals; Arachidonic Acids; Bicuculline; Endocannabinoids; Fear; GABA-A Receptor Agonists; | 2017 |
Inhibition of GABA A receptor improved spatial memory impairment in the local model of demyelination in rat hippocampus.
Topics: Animals; Avoidance Learning; Bicuculline; Demyelinating Diseases; Disease Models, Animal; GABA-A Rec | 2018 |
Modulation of muscimol state-dependent memory by α2-adrenoceptors of the dorsal hippocampal area.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Avoidance Le | 2013 |
Basolateral amygdala GABA-A receptors mediate stress-induced memory retrieval impairment in rats.
Topics: Amygdala; Animals; Behavior, Animal; Bicuculline; Disease Models, Animal; GABA-A Receptor Agonists; | 2014 |
GABA(A) receptors in the central amygdala are involved in memory retention deficits induced by cannabinoids in rats.
Topics: Amnesia; Animals; Avoidance Learning; Benzoxazines; Bicuculline; Cannabinoids; Central Amygdaloid Nu | 2015 |
Anterior cingulate cortex inactivation impairs rodent visual selective attention and prospective memory.
Topics: Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; Cues; Functional Later | 2016 |
The role of CA3 GABAA receptors on anxiolytic-like behaviors and avoidance memory deficit induced by NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Avoidance Learning; Bicuculline; CA3 Region, Hippocam | 2016 |
Additive effect of BLA GABAA receptor mechanism and (+)-MK-801 on memory retention deficit, an isobologram analysis.
Topics: Animals; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; GABA-A Receptor Ago | 2016 |
Temporary inactivation reveals that the CA1 region of the mouse dorsal hippocampus plays an equivalent role in the retrieval of long-term object memory and spatial memory.
Topics: Animals; Behavior, Animal; CA1 Region, Hippocampal; GABA-A Receptor Agonists; Male; Memory Disorders | 2016 |
Transient oligemia is associated with long-term changes in binding densities of cortical inhibitory GABAA receptors in the rat brain.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Disease Models, Animal; Down-Regulation; GABA Agonis | 2009 |
Disconnection of the hippocampal-perirhinal cortical circuits severely disrupts object-place paired associative memory.
Topics: Animals; Association Learning; Discrimination, Psychological; Disease Models, Animal; Entorhinal Cor | 2010 |
Septal infusions of glucose or pyruvate, but not fructose, produce avoidance deficits when co-infused with the GABA agonist muscimol.
Topics: Animals; Avoidance Learning; Fructose; GABA Agonists; Glucose; Male; Memory Disorders; Muscimol; Pyr | 2003 |
Amygdalar inactivation blocks stress-induced impairments in hippocampal long-term potentiation and spatial memory.
Topics: Amygdala; Animals; Corticosterone; Drug Administration Schedule; Electroshock; GABA Agonists; GABA-A | 2005 |
Hippocampal infusions of pyruvate reverse the memory-impairing effects of septal muscimol infusions.
Topics: Animals; Avoidance Learning; Electroshock; GABA Agonists; Hippocampus; Male; Memory Disorders; Memor | 2005 |
Temporary inactivation of the dorsal hippocampus induces a transient impairment in retrieval of aversive memory.
Topics: Animals; Avoidance Learning; Behavior, Animal; GABA Agonists; Hippocampus; Inhibition, Psychological | 2007 |
Effect of histamine on muscimol-induced working memory deficits in radial maze performance.
Topics: Animals; Brain Chemistry; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; GA | 2007 |
Hippocampal infusions of glucose reverse memory deficits produced by co-infusions of a GABA receptor agonist.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; GABA Agonists; gamma-A | 2008 |
The memory-impairing effects of septal GABA receptor activation involve GABAergic septo-hippocampal projection neurons.
Topics: Animals; GABA Agonists; Hippocampus; Male; Memory; Memory Disorders; Muscarinic Antagonists; Muscimo | 2007 |
Excitotoxic basolateral amygdala lesions potentiate the memory impairment effect of muscimol injected into the medial septal area.
Topics: Amygdala; Animals; Avoidance Learning; GABA Agonists; Infusions, Parenteral; Male; Maze Learning; Me | 1999 |