muscimol has been researched along with Learning Disabilities in 7 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The sensitivity of prenatal protein malnourished rats to the amnestic properties of the direct GABAA receptor agonist muscimol and the selective benzodiazepine (BZ) receptor agonist, CL218,872, was studied in the male offspring of rats provided with a protein deficient diet (6% casein) for 5 weeks prior to mating and throughout pregnancy." | 3.72 | Spatial learning deficits induced by muscimol and CL218,872: lack of effect of prenatal malnutrition. ( Bonnie, KE; Duran, P; Galler, JR; Hudson, JL; Shultz, PL; Tonkiss, J, 2003) |
| "Several studies have shown that sleep deprivation produces deficits in learning tasks, but mechanisms underlying these effects remain unclear." | 1.33 | Learning deficits induced by sleep deprivation and recovery are not associated with altered [(3)H]muscimol and [(3)H]flunitrazepam binding. ( Dubiela, FP; Hipólide, DC; Moreira, KM; Nobrega, JN; Oliveira, MG; Tufik, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nasehi, M | 1 |
| Roghani, F | 1 |
| Ebrahimi-Ghiri, M | 1 |
| Zarrindast, MR | 1 |
| Peters, GJ | 1 |
| David, CN | 1 |
| Marcus, MD | 1 |
| Smith, DM | 1 |
| Laurent, V | 1 |
| Westbrook, RF | 1 |
| Burke, KA | 1 |
| Takahashi, YK | 1 |
| Correll, J | 1 |
| Brown, PL | 1 |
| Schoenbaum, G | 1 |
| Tonkiss, J | 1 |
| Shultz, PL | 1 |
| Bonnie, KE | 1 |
| Hudson, JL | 1 |
| Duran, P | 1 |
| Galler, JR | 1 |
| Dubiela, FP | 1 |
| Oliveira, MG | 1 |
| Moreira, KM | 1 |
| Nobrega, JN | 1 |
| Tufik, S | 1 |
| Hipólide, DC | 1 |
| Waddell, J | 1 |
| Bangasser, DA | 1 |
| Shors, TJ | 1 |
7 other studies available for muscimol and Learning Disabilities
| Article | Year |
|---|---|
Role of the amygdala GABA-A receptors in ACPA-induced deficits during conditioned fear learning.
Topics: Amygdala; Animals; Arachidonic Acids; Bicuculline; Endocannabinoids; Fear; GABA-A Receptor Agonists; | 2017 |
The medial prefrontal cortex is critical for memory retrieval and resolving interference.
Topics: Analysis of Variance; Animals; Attention; Discrimination Learning; GABA-A Receptor Agonists; Hippoca | 2013 |
Inactivation of the infralimbic but not the prelimbic cortex impairs consolidation and retrieval of fear extinction.
Topics: Animals; Behavior, Animal; Conditioning, Classical; Electroshock; Extinction, Psychological; Fear; F | 2009 |
Orbitofrontal inactivation impairs reversal of Pavlovian learning by interfering with 'disinhibition' of responding for previously unrewarded cues.
Topics: Animals; Baclofen; Conditioning, Classical; Drug Combinations; GABA Agonists; Inhibition, Psychologi | 2009 |
Spatial learning deficits induced by muscimol and CL218,872: lack of effect of prenatal malnutrition.
Topics: Animals; Body Weight; Female; GABA Agonists; GABA-A Receptor Agonists; Learning Disabilities; Motor | 2003 |
Learning deficits induced by sleep deprivation and recovery are not associated with altered [(3)H]muscimol and [(3)H]flunitrazepam binding.
Topics: Animals; Autoradiography; Avoidance Learning; Brain; Flunitrazepam; GABA Agonists; GABA Modulators; | 2005 |
The basolateral nucleus of the amygdala is necessary to induce the opposing effects of stressful experience on learning in males and females.
Topics: Amygdala; Animals; Conditioning, Eyelid; Female; GABA Agonists; gamma-Aminobutyric Acid; Learning; L | 2008 |