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muscimol and Ischemic Attack, Transient

muscimol has been researched along with Ischemic Attack, Transient in 10 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
"The treatment of pentobarbital caused a significant alteration in the binding of [3H]naloxone and [3H]muscimol in various brain areas 5 h after ischemia."1.29Effect of pentobarbital on postischemic MK-801, muscimol, and naloxone bindings in the gerbil brain. ( Araki, T; Kanai, Y; Kato, H; Kogure, K, 1994)
"[3H]Muscimol was used to label the GABAA receptors and [3H]flunitrazepam to label central type benzodiazepine receptors."1.27GABA and benzodiazepine receptors in the gerbil brain after transient ischemia: demonstration by quantitative receptor autoradiography. ( Kogure, K; Onodera, H; Sato, G, 1987)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's5 (50.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, Y2
Lei, Z2
Xu, ZC2
Blanco, GD1
Sommer, C1
Fahrner, A1
Kiessling, M1
Rossignol, P1
Claperon, N1
Durussel, JJ1
Kanai, Y3
Araki, T3
Kato, H3
Kogure, K4
Murakami, F1
Mileson, BE1
Ehrmann, ML1
Schwartz, RD1
Samochocki, M1
Strosznajder, J1
Onodera, H1
Sato, G1

Other Studies

10 other studies available for muscimol and Ischemic Attack, Transient

ArticleYear
Enhancement of inhibitory synaptic transmission in large aspiny neurons after transient cerebral ischemia.
    Neuroscience, 2009, Mar-17, Volume: 159, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Biophysics;

2009
Increased GAD expression in the striatum after transient cerebral ischemia.
    Molecular and cellular neurosciences, 2010, Volume: 45, Issue:4

    Topics: Animals; Blotting, Western; Corpus Striatum; Fluorescent Antibody Technique; GABA-A Receptor Agonist

2010
Postischemic neuroprotection in the ischemia-tolerant state gerbil hippocampus is associated with increased ligand binding to inhibitory GABA(A) receptors.
    Acta neuropathologica, 2003, Volume: 105, Issue:3

    Topics: Animals; Autoradiography; Binding, Competitive; Gerbillinae; Hippocampus; Ischemic Attack, Transient

2003
[Protective effects of muscimol on acute brain ischemia in the rat (author's transl)].
    Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie, 1982, Mar-15, Volume: 294, Issue:11

    Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Ischemic Attack, Transient; Kinetics; Male; Muscimol; Ox

1982
Effect of pentobarbital on postischemic MK-801, muscimol, and naloxone bindings in the gerbil brain.
    Brain research, 1994, Sep-19, Volume: 657, Issue:1-2

    Topics: Animals; Brain; Dizocilpine Maleate; Gerbillinae; Ischemic Attack, Transient; Male; Muscimol; Naloxo

1994
Postischemic changes in the binding of excitatory and inhibitory neurotransmitters in the gerbil brain.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:4

    Topics: Animals; Autoradiography; Brain Chemistry; Dizocilpine Maleate; gamma-Aminobutyric Acid; Gerbillinae

1993
Alterations in the gamma-aminobutyric acid-gated chloride channel following transient forebrain ischemia in the gerbil.
    Journal of neurochemistry, 1992, Volume: 58, Issue:2

    Topics: Animals; Autoradiography; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlori

1992
Long-term changes in gerbil brain neurotransmitter receptors following transient cerebral ischaemia.
    British journal of pharmacology, 1992, Volume: 107, Issue:2

    Topics: Adenosine; Animals; Autoradiography; Binding Sites; Brain; Dizocilpine Maleate; Gerbillinae; Hippoca

1992
Brain ischemia increased high affinity binding of [3H]muscimol into synaptic plasma membrane receptor.
    Acta neurobiologiae experimentalis, 1990, Volume: 50, Issue:4-5

    Topics: Animals; Brain; Gerbillinae; Ischemic Attack, Transient; Kinetics; Muscimol; Rats; Rats, Inbred Stra

1990
GABA and benzodiazepine receptors in the gerbil brain after transient ischemia: demonstration by quantitative receptor autoradiography.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1987, Volume: 7, Issue:1

    Topics: Animals; Autoradiography; Brain Chemistry; Flunitrazepam; Gerbillinae; Hippocampus; Ischemic Attack,

1987