Page last updated: 2024-10-31

muscimol and Ischemia

muscimol has been researched along with Ischemia in 3 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Either muscimol (a GABA-A agonist) or bicuculline (a GABA-A antagonist) was administered intravenously to groups of rabbits exposed to reversible spinal cord ischemia induced by temporary occlusion of the infrarenal aorta."7.69Effect of gamma-aminobutyric acid modulation on neuronal ischemia in rabbits. ( Madden, KP, 1994)
"Either muscimol (a GABA-A agonist) or bicuculline (a GABA-A antagonist) was administered intravenously to groups of rabbits exposed to reversible spinal cord ischemia induced by temporary occlusion of the infrarenal aorta."3.69Effect of gamma-aminobutyric acid modulation on neuronal ischemia in rabbits. ( Madden, KP, 1994)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Madden, KP1
Zeevalk, GD1
Nicklas, WJ1
Hao, JX1
Xu, XJ1
Yu, YX1
Seiger, A1
Wiesenfeld-Hallin, Z1

Other Studies

3 other studies available for muscimol and Ischemia

ArticleYear
Effect of gamma-aminobutyric acid modulation on neuronal ischemia in rabbits.
    Stroke, 1994, Volume: 25, Issue:11

    Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Injections, Intrave

1994
Activity at the GABA transporter contributes to acute cellular swelling produced by metabolic impairment in retina.
    Vision research, 1997, Volume: 37, Issue:24

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Chick Embryo; Culture Techniq

1997
Baclofen reverses the hypersensitivity of dorsal horn wide dynamic range neurons to mechanical stimulation after transient spinal cord ischemia; implications for a tonic GABAergic inhibitory control of myelinated fiber input.
    Journal of neurophysiology, 1992, Volume: 68, Issue:2

    Topics: Animals; Baclofen; Decerebrate State; Electric Stimulation; gamma-Aminobutyric Acid; Ischemia; Musci

1992