muscimol has been researched along with Inflammation in 5 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Genistein reversal was partially blocked by the dynamin inhibitor peptide P4." | 1.38 | Inflammation-induced shift in spinal GABA(A) signaling is associated with a tyrosine kinase-dependent increase in GABA(A) current density in nociceptive afferents. ( Dua, S; Gold, MS; Zhu, Y, 2012) |
| "The SP-induced hyperalgesia was both GABA(A) and NMDA receptor-dependent after pre- and post-treatment with selective antagonists at the spinal level." | 1.36 | Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla. ( Dubner, R; Guo, W; Lagraize, SC; Ren, K; Wei, F; Yang, K, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shao, FB | 1 |
| Fang, JF | 1 |
| Wang, SS | 1 |
| Qiu, MT | 1 |
| Xi, DN | 1 |
| Jin, XM | 1 |
| Liu, JG | 1 |
| Shao, XM | 1 |
| Shen, Z | 1 |
| Liang, Y | 1 |
| Fang, JQ | 1 |
| Du, JY | 1 |
| Zhang, C | 1 |
| Chen, RX | 1 |
| Zhang, Y | 1 |
| Wang, J | 1 |
| Liu, FY | 1 |
| Cai, J | 1 |
| Liao, FF | 1 |
| Xu, FQ | 1 |
| Yi, M | 1 |
| Wan, Y | 1 |
| Lagraize, SC | 1 |
| Guo, W | 1 |
| Yang, K | 1 |
| Wei, F | 1 |
| Ren, K | 1 |
| Dubner, R | 1 |
| Zhu, Y | 1 |
| Dua, S | 1 |
| Gold, MS | 2 |
| Anseloni, VC | 1 |
5 other studies available for muscimol and Inflammation
| Article | Year |
|---|---|
Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Central Nervous System Sensitization; Chronic Pain; Clozapine | 2021 |
Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain.
Topics: Animals; Chronic Pain; Extracellular Space; Freund's Adjuvant; GABAergic Neurons; gamma-Aminobutyric | 2017 |
Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla.
Topics: Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Dizocilp | 2010 |
Inflammation-induced shift in spinal GABA(A) signaling is associated with a tyrosine kinase-dependent increase in GABA(A) current density in nociceptive afferents.
Topics: Action Potentials; Animals; Calcium; Freund's Adjuvant; GABA-A Receptor Agonists; GABA-A Receptor An | 2012 |
Inflammation-induced shift in the valence of spinal GABA-A receptor-mediated modulation of nociception in the adult rat.
Topics: Animals; Antineoplastic Agents; Flumazenil; Freund's Adjuvant; GABA Agonists; GABA Antagonists; GABA | 2008 |