muscimol has been researched along with Inadequate Sleep in 8 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice." | 7.74 | Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008) |
| "White rats were subjected to REM-sleep deprivation during 14-20 days of pregnancy." | 5.28 | [The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy]. ( Zabludovskiĭ, AL; Zhulin, VV, 1989) |
| " In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice." | 3.74 | Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008) |
| "Treatment with melatonin (5 and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared to control (sleep deprived)." | 1.37 | Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice. ( Kumar, A; Kumar, P; Singh, A, 2011) |
| "Treatment with melatonin (5 mg/kg and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared with control (sleep-deprived)." | 1.35 | Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice. ( Kumar, A; Singh, A, 2009) |
| "Several studies have shown that sleep deprivation produces deficits in learning tasks, but mechanisms underlying these effects remain unclear." | 1.33 | Learning deficits induced by sleep deprivation and recovery are not associated with altered [(3)H]muscimol and [(3)H]flunitrazepam binding. ( Dubiela, FP; Hipólide, DC; Moreira, KM; Nobrega, JN; Oliveira, MG; Tufik, S, 2005) |
| "White rats were subjected to REM-sleep deprivation during 14-20 days of pregnancy." | 1.28 | [The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy]. ( Zabludovskiĭ, AL; Zhulin, VV, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sapin, E | 1 |
| Lapray, D | 1 |
| Bérod, A | 1 |
| Goutagny, R | 1 |
| Léger, L | 1 |
| Ravassard, P | 1 |
| Clément, O | 1 |
| Hanriot, L | 1 |
| Fort, P | 1 |
| Luppi, PH | 1 |
| Singh, A | 3 |
| Kumar, A | 3 |
| Wei, H | 1 |
| Hao, B | 1 |
| Huang, JL | 1 |
| Ma, AN | 1 |
| Li, XY | 1 |
| Wang, YX | 1 |
| Pertovaara, A | 1 |
| Kumar, P | 1 |
| Dubiela, FP | 1 |
| Oliveira, MG | 1 |
| Moreira, KM | 1 |
| Nobrega, JN | 1 |
| Tufik, S | 1 |
| Hipólide, DC | 1 |
| Frank, MG | 1 |
| Jha, SK | 1 |
| Coleman, T | 1 |
| Zhulin, VV | 1 |
| Zabludovskiĭ, AL | 1 |
8 other studies available for muscimol and Inadequate Sleep
| Article | Year |
|---|---|
Localization of the brainstem GABAergic neurons controlling paradoxical (REM) sleep.
Topics: Animals; Brain Stem; Disorders of Excessive Somnolence; GABA Plasma Membrane Transport Proteins; gam | 2009 |
Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Catalase; Dose-Response Relationship, Drug; Flumaze | 2008 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Fem | 2009 |
Intrathecal administration of a gap junction decoupler, an inhibitor of Na(+)-K(+)-2Cl(-) cotransporter 1, or a GABA(A) receptor agonist attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat.
Topics: Animals; Behavior, Animal; Bumetanide; Carbenoxolone; Chloride Channels; GABA Agonists; Gap Junction | 2010 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Flumazenil; GABA Modulators; gamma-Aminobutyric Ac | 2011 |
Learning deficits induced by sleep deprivation and recovery are not associated with altered [(3)H]muscimol and [(3)H]flunitrazepam binding.
Topics: Animals; Autoradiography; Avoidance Learning; Brain; Flunitrazepam; GABA Agonists; GABA Modulators; | 2005 |
Blockade of postsynaptic activity in sleep inhibits developmental plasticity in visual cortex.
Topics: Action Potentials; Animals; Cats; Dominance, Ocular; Electroencephalography; Electromyography; Excit | 2006 |
[The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy].
Topics: Animals; Cerebral Cortex; Female; Muscimol; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rece | 1989 |