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muscimol and Hypoglycemia

muscimol has been researched along with Hypoglycemia in 2 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.

Research Excerpts

ExcerptRelevanceReference
"Hypoglycemia provokes a multifaceted counterregulatory response involving the sympathoadrenal system, stimulation of glucagon secretion, and the hypothalamo-pituitary-adrenal axis that is commonly impaired in diabetes."7.73Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia. ( Chan, O; Ding, Y; McCrimmon, RJ; Sherwin, RS; Zhu, W, 2006)
"Hypoglycemia provokes a multifaceted counterregulatory response involving the sympathoadrenal system, stimulation of glucagon secretion, and the hypothalamo-pituitary-adrenal axis that is commonly impaired in diabetes."3.73Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia. ( Chan, O; Ding, Y; McCrimmon, RJ; Sherwin, RS; Zhu, W, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, O1
Zhu, W1
Ding, Y1
McCrimmon, RJ1
Sherwin, RS1
Velísková, J1
Chudomel, O1
Poon, KL1
Marshall, B1
Velísek, L1

Other Studies

2 other studies available for muscimol and Hypoglycemia

ArticleYear
Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia.
    Diabetes, 2006, Volume: 55, Issue:4

    Topics: Animals; Bicuculline; Blood Glucose; Corticosterone; Epinephrine; GABA Antagonists; Glucagon; Glucos

2006
The involvement of the substantia nigra pars reticulata in hypoglycemic seizures.
    Epilepsia, 2007, Volume: 48 Suppl 5

    Topics: Animals; Baclofen; Behavior, Animal; Disease Models, Animal; Fasting; GABA-A Receptor Agonists; gamm

2007