Page last updated: 2024-10-31

muscimol and Hyperphagia

muscimol has been researched along with Hyperphagia in 6 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Hyperphagia: Ingestion of a greater than optimal quantity of food.

Research Excerpts

ExcerptRelevanceReference
" The present study explored how two mPFC subregions, the infralimbic (IL) and prelimbic (PRL) cortices, regulate sucrose hyperphagia elicited specifically by a neurochemical manipulation of the agranular/dysgranular region of gustatory insula (AI/DI)."4.12Eating driven by the gustatory insula: contrasting regulation by infralimbic vs. prelimbic cortices. ( Baldo, BA; Giacomini, JL; Sadeghian, K, 2022)
" Interestingly, benzodiazepine receptor antagonist flumazenil (5 ng/rat, icv), augmented the orexin-A (30 nM/rat, icv) induced hyperphagia; the effect may be attributed to the intrinsic activity of the agent."3.73GABA(A) receptors mediate orexin-A induced stimulation of food intake. ( Carta, A; Chopde, CT; Kokare, DM; Patole, AM; Subhedar, NK, 2006)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Giacomini, JL1
Sadeghian, K1
Baldo, BA2
Tejas-Juárez, JG1
Cruz-Martínez, AM1
López-Alonso, VE1
García-Iglesias, B1
Mancilla-Díaz, JM1
Florán-Garduño, B1
Escartín-Pérez, RE1
Taha, SA1
Katsuura, Y1
Noorvash, D1
Seroussi, A1
Fields, HL1
Kokare, DM1
Patole, AM1
Carta, A1
Chopde, CT1
Subhedar, NK1
Alsene, KM1
Negron, A1
Kelley, AE1
Bendotti, C1
Garattini, S1
Samanin, R1

Other Studies

6 other studies available for muscimol and Hyperphagia

ArticleYear
Eating driven by the gustatory insula: contrasting regulation by infralimbic vs. prelimbic cortices.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2022, Volume: 47, Issue:7

    Topics: Animals; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hyperphagia; Muscimol; Prefrontal Cortex; Rats

2022
Stimulation of dopamine D4 receptors in the paraventricular nucleus of the hypothalamus of male rats induces hyperphagia: involvement of glutamate.
    Physiology & behavior, 2014, Jun-22, Volume: 133

    Topics: Animals; Benzamides; Corticosterone; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; Eat

2014
Convergent, not serial, striatal and pallidal circuits regulate opioid-induced food intake.
    Neuroscience, 2009, Jul-07, Volume: 161, Issue:3

    Topics: Animals; Catheterization; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Feeding Behavior; GABA Agonis

2009
GABA(A) receptors mediate orexin-A induced stimulation of food intake.
    Neuropharmacology, 2006, Volume: 50, Issue:1

    Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Eating; Flumazenil; GABA Agonists; GABA Antagon

2006
Hyperphagia induced by GABAA receptor-mediated inhibition of the nucleus accumbens shell: dependence on intact neural output from the central amygdaloid region.
    Behavioral neuroscience, 2005, Volume: 119, Issue:5

    Topics: Amygdala; Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Dose-Response Relatio

2005
Hyperphagia caused by muscimol injection in the nucleus raphe dorsalis of rats: its control by 5-hydroxytryptamine in the nucleus accumbens.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:7

    Topics: Animals; Feeding and Eating Disorders; Hyperphagia; Injections; Male; Muscimol; Norfenfluramine; Nuc

1986