Page last updated: 2024-10-31

muscimol and Genetic Predisposition

muscimol has been researched along with Genetic Predisposition in 3 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Research Excerpts

ExcerptRelevanceReference
"gamma-Aminobutyric acid (GABA) is a major neurotransmitter in AMG, and histamine receptor activation is also reported to stimulate GABA release."1.31Modulation of audiogenically kindled seizures by gamma-aminobutyric acid-related mechanisms in the amygdala. ( Faingold, CL; Feng, HJ; Naritoku, DK; Randall, ME, 2001)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Molnar, LR1
Fleming, WW1
Taylor, DA1
Feng, HJ1
Naritoku, DK1
Randall, ME1
Faingold, CL1
Buck, KJ1
McQuilkin, SJ1
Harris, RA1

Other Studies

3 other studies available for muscimol and Genetic Predisposition

ArticleYear
Alterations in neuronal gamma-aminobutyric acid(A) receptor responsiveness in genetic models of seizure susceptibility with different expression patterns.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:3

    Topics: Age Factors; Animals; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Genetic P

2000
Modulation of audiogenically kindled seizures by gamma-aminobutyric acid-related mechanisms in the amygdala.
    Experimental neurology, 2001, Volume: 172, Issue:2

    Topics: Acoustic Stimulation; Amygdala; Animals; Epilepsy; GABA Agonists; gamma-Aminobutyric Acid; Genetic P

2001
Modulation of gamma-aminobutyric acidA receptor-operated chloride channels by benzodiazepine inverse agonists is related to genetic differences in ethanol withdrawal seizure severity.
    Journal of neurochemistry, 1991, Volume: 57, Issue:6

    Topics: Animals; Benzodiazepines; Carbolines; Chloride Channels; Chlorides; Convulsants; Ethanol; Flunitraze

1991