muscimol has been researched along with Epilepsy, Tonic-Clonic in 3 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giorgi, FS | 1 |
| Velísková, J | 1 |
| Chudomel, O | 1 |
| Kyrozis, A | 1 |
| Moshé, SL | 1 |
| Narita, M | 1 |
| Takahashi, Y | 1 |
| Suzuki, T | 1 |
| Misawa, M | 1 |
| Nagase, H | 1 |
| MacGregor, DG | 1 |
| Graham, DI | 1 |
| Stone, TW | 1 |
3 other studies available for muscimol and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
The role of substantia nigra pars reticulata in modulating clonic seizures is determined by testosterone levels during the immediate postnatal period.
Topics: Animals; Animals, Newborn; Convulsants; Dihydrotestosterone; Electrophysiology; Epilepsy, Tonic-Clon | 2007 |
An ATP-sensitive potassium channel blocker abolishes the potentiating effect of morphine on the bicuculline-induced convulsion in mice.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Bicuculline; Epilepsy, Tonic-Clonic; Glyburide; I | 1993 |
The attenuation of kainate-induced neurotoxicity by chlormethiazole and its enhancement by dizocilpine, muscimol, and adenosine receptor agonists.
Topics: Adenosine; Animals; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Synergism; Drug The | 1997 |