muscimol has been researched along with Epilepsies, Partial in 3 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kohane, DS | 1 |
| Holmes, GL | 1 |
| Chau, Y | 1 |
| Zurakowski, D | 1 |
| Langer, R | 1 |
| Cha, BH | 1 |
| Kim, DY | 1 |
| Fenoglio, KA | 1 |
| Simeone, TA | 1 |
| Coons, SW | 1 |
| Wu, J | 1 |
| Chang, Y | 1 |
| Kerrigan, JF | 1 |
| Rho, JM | 1 |
| Ono, K | 1 |
| Wada, JA | 1 |
3 other studies available for muscimol and Epilepsies, Partial
| Article | Year |
|---|---|
Effectiveness of muscimol-containing microparticles against pilocarpine-induced focal seizures.
Topics: Animals; Anticonvulsants; Drug Carriers; Drug Implants; Epilepsies, Partial; GABA-A Receptor Agonist | 2002 |
GABAA receptor-mediated activation of L-type calcium channels induces neuronal excitation in surgically resected human hypothalamic hamartomas.
Topics: Action Potentials; Adolescent; Adult; Calcium Channels, L-Type; Child, Preschool; Chloride Channels; | 2008 |
Facilitation of premotor cortical seizure development by intranigral muscimol.
Topics: Animals; Dopamine; Epilepsies, Partial; gamma-Aminobutyric Acid; Male; Microinjections; Motor Cortex | 1987 |