muscimol has been researched along with Demyelinating Diseases in 1 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bicuculline treatment significantly reduced demyelination extension and increased the level of MBP expression." | 1.48 | Inhibition of GABA A receptor improved spatial memory impairment in the local model of demyelination in rat hippocampus. ( Afghani, A; Ashrafpour, M; Ashrafpour, S; Dehghan, S; Ebrahim Tabar, F; Gol, M; Mousavi Majd, A; Pourabdolhossein, F, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mousavi Majd, A | 1 |
| Ebrahim Tabar, F | 1 |
| Afghani, A | 1 |
| Ashrafpour, S | 1 |
| Dehghan, S | 1 |
| Gol, M | 1 |
| Ashrafpour, M | 1 |
| Pourabdolhossein, F | 1 |
1 other study available for muscimol and Demyelinating Diseases
| Article | Year |
|---|---|
Inhibition of GABA A receptor improved spatial memory impairment in the local model of demyelination in rat hippocampus.
Topics: Animals; Avoidance Learning; Bicuculline; Demyelinating Diseases; Disease Models, Animal; GABA-A Rec | 2018 |