muscimol has been researched along with Delayed Effects, Prenatal Exposure in 16 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| "White rats were subjected to REM-sleep deprivation during 14-20 days of pregnancy." | 5.28 | [The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy]. ( Zabludovskiĭ, AL; Zhulin, VV, 1989) |
| "Prenatal exposure to valproic acid (VPA) enhances the risk for later development of autism spectrum disorders (ASD)." | 3.85 | Increased GABAA receptor binding in amygdala after prenatal administration of valproic acid to rats. ( Bertelsen, F; Drasbek, KR; Folloni, D; Landau, AM; Møller, A; Scheel-Krüger, J, 2017) |
| "The sensitivity of prenatal protein malnourished rats to the amnestic properties of the direct GABAA receptor agonist muscimol and the selective benzodiazepine (BZ) receptor agonist, CL218,872, was studied in the male offspring of rats provided with a protein deficient diet (6% casein) for 5 weeks prior to mating and throughout pregnancy." | 3.72 | Spatial learning deficits induced by muscimol and CL218,872: lack of effect of prenatal malnutrition. ( Bonnie, KE; Duran, P; Galler, JR; Hudson, JL; Shultz, PL; Tonkiss, J, 2003) |
| "Muscimol treatment in the saline-exposed group increased the mount and intromission latencies." | 1.38 | Maternal exposure to picrotoxin modifies the response of the GABAA receptor during sexual behavior of adult male rat offspring. ( Baso, AC; Bernardi, MM; Felicio, LF; Kirsten, TB; Prosdocimi, FC; Teodorov, E, 2012) |
| "Phenobarbital (PhB) was administered to pregnant mice during days 9-18 of gestation." | 1.28 | Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors. ( Fares, F; Gavish, M; Pick, CG; Weizman, A; Yanai, J, 1990) |
| "White rats were subjected to REM-sleep deprivation during 14-20 days of pregnancy." | 1.28 | [The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy]. ( Zabludovskiĭ, AL; Zhulin, VV, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Aghighi Bidgoli, F | 1 |
| Salami, M | 1 |
| Talaei, SA | 1 |
| Delhaes, F | 1 |
| Fournier, S | 1 |
| Tolsa, JF | 1 |
| Peyter, AC | 1 |
| Bairam, A | 1 |
| Kinkead, R | 1 |
| Bertelsen, F | 1 |
| Møller, A | 1 |
| Folloni, D | 1 |
| Drasbek, KR | 1 |
| Scheel-Krüger, J | 1 |
| Landau, AM | 1 |
| Bernardi, MM | 1 |
| Kirsten, TB | 1 |
| Teodorov, E | 1 |
| Baso, AC | 1 |
| Prosdocimi, FC | 1 |
| Felicio, LF | 1 |
| Tonkiss, J | 1 |
| Shultz, PL | 1 |
| Bonnie, KE | 1 |
| Hudson, JL | 1 |
| Duran, P | 1 |
| Galler, JR | 1 |
| Koff, JM | 1 |
| Miller, LG | 2 |
| Blaine, K | 1 |
| Gasser, K | 1 |
| Conway, S | 1 |
| Tkachuk, SS | 1 |
| Pishak, VP | 1 |
| Myslyts'kyĭ, VF | 1 |
| Ricceri, L | 1 |
| Venerosi, A | 1 |
| Valanzano, A | 1 |
| Sorace, A | 1 |
| Alleva, E | 1 |
| Luk, KC | 1 |
| Sadikot, AF | 1 |
| Bailey, CD | 1 |
| Brien, JF | 1 |
| Reynolds, JN | 1 |
| Fares, F | 1 |
| Weizman, A | 1 |
| Pick, CG | 1 |
| Yanai, J | 1 |
| Gavish, M | 1 |
| Zhulin, VV | 2 |
| Zabludovskiĭ, AL | 2 |
| Roy, RB | 1 |
| Weill, CL | 1 |
| Lopez, F | 1 |
| Rothe, T | 1 |
| Middleton-Price, H | 1 |
| Bigl, V | 1 |
16 other studies available for muscimol and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Environmental enrichment restores impaired spatial memory and synaptic plasticity in prenatally stress exposed rats: The role of GABAergic neurotransmission.
Topics: Animals; Bicuculline; Corticosterone; Environment; Female; GABA-A Receptor Agonists; GABA-A Receptor | 2020 |
Consequences of gestational stress on GABAergic modulation of respiratory activity in developing newborn pups.
Topics: Animals; Animals, Newborn; Brain Stem; Cervical Vertebrae; Dose-Response Relationship, Drug; Female; | 2014 |
Increased GABAA receptor binding in amygdala after prenatal administration of valproic acid to rats.
Topics: Amygdala; Animals; Autism Spectrum Disorder; Autoradiography; Azides; Benzodiazepines; Carbon Radioi | 2017 |
Maternal exposure to picrotoxin modifies the response of the GABAA receptor during sexual behavior of adult male rat offspring.
Topics: Animals; Female; GABA Antagonists; GABA-A Receptor Agonists; Injections, Subcutaneous; Lactation; Ma | 2012 |
Spatial learning deficits induced by muscimol and CL218,872: lack of effect of prenatal malnutrition.
Topics: Animals; Body Weight; Female; GABA Agonists; GABA-A Receptor Agonists; Learning Disabilities; Motor | 2003 |
Prenatal lorazepam exposure: 4. Persistent alterations in pentylenetetrazole-induced seizure threshold and GABA-dependent chloride uptake after prenatal lorazepam exposure.
Topics: Animals; Brain Chemistry; Chlorides; Chlorine; Female; gamma-Aminobutyric Acid; Lorazepam; Mice; Mus | 1995 |
Influence of fetal alcohol exposure on the GABAergic regulation of growth hormone release in postnatal rats.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Body Weight; Central Nervous System Depressants | 1999 |
[The mechanisms of the GABA-ergic regulation of beta-endorphin levels in the hypothalamic structures of prenatally stressed male rats].
Topics: Animals; Baclofen; beta-Endorphin; Brain Chemistry; Female; GABA Agonists; Hypothalamus, Middle; Mal | 2000 |
Prenatal AZT or 3TC and mouse development of locomotor activity and hot-plate responding upon administration of the GABA(A) receptor agonist muscimol.
Topics: Animals; Anti-HIV Agents; Female; GABA Agonists; GABA-A Receptor Agonists; Habituation, Psychophysio | 2001 |
GABA promotes survival but not proliferation of parvalbumin-immunoreactive interneurons in rodent neostriatum: an in vivo study with stereology.
Topics: Animals; Animals, Newborn; Bicuculline; Cell Count; Cell Division; Cell Movement; Cell Survival; Emb | 2001 |
Chronic prenatal ethanol exposure increases GABA(A) receptor subunit protein expression in the adult guinea pig cerebral cortex.
Topics: Administration, Oral; Animals; Body Weight; Cerebral Cortex; Dizocilpine Maleate; Drug Administratio | 2001 |
Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors.
Topics: Aging; Animals; Brain; Female; Flunitrazepam; Male; Mice; Muscimol; Phenobarbital; Pregnancy; Prenat | 1990 |
[The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy].
Topics: Animals; Cerebral Cortex; Female; Muscimol; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rece | 1989 |
Persistent alterations in GABAA receptor binding and function after prenatal lorazepam administration in the chick.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Chickens; | 1989 |
The ontogeny of GABA receptors and glutamic acid decarboxylase in regions of the rat brain. Effect of prenatal exposure to diazepam.
Topics: Animals; Brain; Diazepam; Female; Glutamate Decarboxylase; Muscimol; Pregnancy; Prenatal Exposure De | 1988 |
[Peculiarities of H3-muscimol binding to neocortex membranes of rats exposed to the effects of ethanol in the prenatal period].
Topics: Age Factors; Animals; Cerebral Cortex; Ethanol; Female; Male; Muscimol; Pregnancy; Prenatal Exposure | 1988 |