muscimol has been researched along with Cognition Disorders in 5 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study investigated the possible relation between muscimol-induced long-term depression and barbiturates/benzodiazepine-induced amnesia and attempts to determine the possible effect of pregnenolone sulfate on muscimol-induced long-term depression." | 7.70 | Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate. ( Akhondzadeh, S; Stone, TW, 1998) |
| " The present study investigated the possible relation between muscimol-induced long-term depression and barbiturates/benzodiazepine-induced amnesia and attempts to determine the possible effect of pregnenolone sulfate on muscimol-induced long-term depression." | 3.70 | Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate. ( Akhondzadeh, S; Stone, TW, 1998) |
| " To provide proof of concept for the nomethiazole drug class, selected examples were assayed for restoration of synaptic function in hippocampal slices from AD-transgenic mice, reversal of cognitive deficits, and brain bioavailability of the prodrug and its neuroprotective MZ metabolite." | 1.38 | Design and synthesis of neuroprotective methylthiazoles and modification as NO-chimeras for neurodegenerative therapy. ( Arancio, O; Fa', M; Luo, J; Qin, Z; Tavassoli, E; Teich, AF; Thatcher, GR; VandeVrede, L, 2012) |
| "When muscimol was applied to a portion of area 5 in which the activity in the numerosity-selective cells was recorded, the error rate in the selection task increased significantly." | 1.36 | Deficits in action selection based on numerical information after inactivation of the posterior parietal cortex in monkeys. ( Sawamura, H; Shima, K; Tanji, J, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qin, Z | 1 |
| Luo, J | 1 |
| VandeVrede, L | 1 |
| Tavassoli, E | 1 |
| Fa', M | 1 |
| Teich, AF | 1 |
| Arancio, O | 1 |
| Thatcher, GR | 1 |
| Axelsson, SFA | 1 |
| Horst, NK | 1 |
| Horiguchi, N | 1 |
| Roberts, AC | 1 |
| Robbins, TW | 1 |
| Shirvalkar, PR | 1 |
| Rapp, PR | 1 |
| Shapiro, ML | 1 |
| Sawamura, H | 1 |
| Shima, K | 1 |
| Tanji, J | 1 |
| Akhondzadeh, S | 1 |
| Stone, TW | 1 |
5 other studies available for muscimol and Cognition Disorders
| Article | Year |
|---|---|
Design and synthesis of neuroprotective methylthiazoles and modification as NO-chimeras for neurodegenerative therapy.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Avoidance Learning; Biological Availabil | 2012 |
Flexible versus Fixed Spatial Self-Ordered Response Sequencing: Effects of Inactivation and Neurochemical Modulation of Ventrolateral Prefrontal Cortex.
Topics: Animals; Antipsychotic Agents; Baclofen; Callithrix; Cognition Disorders; Dopamine; Dopamine D2 Rece | 2021 |
Bidirectional changes to hippocampal theta-gamma comodulation predict memory for recent spatial episodes.
Topics: Animals; Behavior, Animal; Brain; Cognition Disorders; Electrodes; Electrophysiology; Fornix, Brain; | 2010 |
Deficits in action selection based on numerical information after inactivation of the posterior parietal cortex in monkeys.
Topics: Action Potentials; Analysis of Variance; Animals; Brain Mapping; Choice Behavior; Cognition Disorder | 2010 |
Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate.
Topics: Amnesia; Animals; Barbiturates; Benzodiazepines; Cognition Disorders; Depression; Diazepam; Drug Syn | 1998 |