muscimol has been researched along with Cleft Palate in 1 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Cleft Palate: Congenital fissure of the soft and/or hard palate, due to faulty fusion.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a second series of experiments we found that the GABA(A) receptor agonist muscimol could rescue the cleft palate phenotype in Gad1 and Viaat mutant embryos." | 3.76 | Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice. ( Condie, BG; Oh, WJ; Summers, R; Westmoreland, JJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oh, WJ | 1 |
| Westmoreland, JJ | 1 |
| Summers, R | 1 |
| Condie, BG | 1 |
1 other study available for muscimol and Cleft Palate
| Article | Year |
|---|---|
Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice.
Topics: Animals; Central Nervous System; Cleft Palate; Crosses, Genetic; Female; Glutamate Decarboxylase; Ho | 2010 |