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muscimol and Cleft Palate, Isolated

muscimol has been researched along with Cleft Palate, Isolated in 1 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Research Excerpts

ExcerptRelevanceReference
" In a second series of experiments we found that the GABA(A) receptor agonist muscimol could rescue the cleft palate phenotype in Gad1 and Viaat mutant embryos."3.76Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice. ( Condie, BG; Oh, WJ; Summers, R; Westmoreland, JJ, 2010)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oh, WJ1
Westmoreland, JJ1
Summers, R1
Condie, BG1

Other Studies

1 other study available for muscimol and Cleft Palate, Isolated

ArticleYear
Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice.
    PloS one, 2010, Mar-19, Volume: 5, Issue:3

    Topics: Animals; Central Nervous System; Cleft Palate; Crosses, Genetic; Female; Glutamate Decarboxylase; Ho

2010