muscimol has been researched along with Chronic Pain in 5 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study investigated the involvement of mediodorsal thalamic (MD) GABA-A receptors in cetirizine/morphine-induced anti-allodynia using a rat model of neuropathic pain." | 4.31 | Pharmacological activation of mediodorsal thalamic GABA-A receptors modulates morphine/cetirizine-induced changes in the prefrontal cortical GFAP expression in a rat model of neuropathic pain. ( Alijanpour, S; Asgharpour-Masouleh, N; Delphi, L; Rezayof, A, 2023) |
| "Thus, mechanical hyperalgesia and allodynia, and the pattern of c-Fos staining in the amygdala subnuclei were evaluated in rats with chronic constriction of the sciatic nerve, as well as sham-operated and naïve rats." | 1.48 | The critical role of amygdala subnuclei in nociceptive and depressive-like behaviors in peripheral neuropathy. ( Antunes, GF; Assis, DV; Gouveia, F; Kuroki, M; Martinez, RCR; Oliveira, CC; Pagano, RL; Santos, LCT; Seno, MDJ, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shao, FB | 1 |
| Fang, JF | 1 |
| Wang, SS | 1 |
| Qiu, MT | 1 |
| Xi, DN | 1 |
| Jin, XM | 1 |
| Liu, JG | 1 |
| Shao, XM | 1 |
| Shen, Z | 1 |
| Liang, Y | 1 |
| Fang, JQ | 1 |
| Du, JY | 1 |
| Asgharpour-Masouleh, N | 1 |
| Rezayof, A | 1 |
| Alijanpour, S | 1 |
| Delphi, L | 1 |
| Seno, MDJ | 1 |
| Assis, DV | 1 |
| Gouveia, F | 1 |
| Antunes, GF | 1 |
| Kuroki, M | 1 |
| Oliveira, CC | 1 |
| Santos, LCT | 1 |
| Pagano, RL | 1 |
| Martinez, RCR | 1 |
| Zhang, C | 1 |
| Chen, RX | 1 |
| Zhang, Y | 1 |
| Wang, J | 1 |
| Liu, FY | 1 |
| Cai, J | 1 |
| Liao, FF | 1 |
| Xu, FQ | 1 |
| Yi, M | 1 |
| Wan, Y | 1 |
| Reichl, S | 1 |
| Augustin, M | 1 |
| Zahn, PK | 1 |
| Pogatzki-Zahn, EM | 1 |
5 other studies available for muscimol and Chronic Pain
| Article | Year |
|---|---|
Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Central Nervous System Sensitization; Chronic Pain; Clozapine | 2021 |
Pharmacological activation of mediodorsal thalamic GABA-A receptors modulates morphine/cetirizine-induced changes in the prefrontal cortical GFAP expression in a rat model of neuropathic pain.
Topics: Animals; Cetirizine; Chronic Pain; Disease Models, Animal; GABA-A Receptor Agonists; Glial Fibrillar | 2023 |
The critical role of amygdala subnuclei in nociceptive and depressive-like behaviors in peripheral neuropathy.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Basolateral Nuclear Complex; Central Amygdaloid Nucle | 2018 |
Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain.
Topics: Animals; Chronic Pain; Extracellular Space; Freund's Adjuvant; GABAergic Neurons; gamma-Aminobutyric | 2017 |
Peripheral and spinal GABAergic regulation of incisional pain in rats.
Topics: Animals; Baclofen; Behavior, Animal; Chronic Pain; gamma-Aminobutyric Acid; Hyperalgesia; Muscimol; | 2012 |