muscimol has been researched along with Cerebrovascular Disorders in 3 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "If muscimol was combined with MK-801 at lower doses of each drug, the combination was neuroprotective (potency ratio of 4." | 1.29 | Combination chemotherapy extends the therapeutic window to 60 minutes after stroke. ( Lonzo, L; Lyden, P; Nunez, S, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lyden, P | 1 |
| Lonzo, L | 1 |
| Nunez, S | 1 |
| Schallert, T | 1 |
| Jones, TA | 1 |
| Lindner, MD | 1 |
| Hashimoto, T | 1 |
| Kimori, M | 1 |
| Nakamura, Y | 1 |
| Kuriyama, K | 1 |
1 review available for muscimol and Cerebrovascular Disorders
| Article | Year |
|---|---|
Multilevel transneuronal degeneration after brain damage. Behavioral events and effects of anticonvulsant gamma-aminobutyric acid-related drugs.
Topics: Animals; Atrophy; Behavior, Animal; Cerebrovascular Disorders; Corpus Striatum; Diazepam; gamma-Amin | 1990 |
2 other studies available for muscimol and Cerebrovascular Disorders
| Article | Year |
|---|---|
Combination chemotherapy extends the therapeutic window to 60 minutes after stroke.
Topics: Animals; Brain; Cerebrovascular Disorders; Dizocilpine Maleate; Drug Therapy, Combination; Excitator | 1995 |
Effect of NC-1100 [1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl) ethanol dihydrochloride] on gamma-aminobutyric acid (GABA) metabolism in rat brain: analysis using stroke-prone spontaneously hypertensive rat.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Animals; Brain; Cerebrovascular Disorders; gamma-Aminobut | 1989 |