muscimol has been researched along with Cerebral Infarction in 5 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Transient focal cerebral ischemia was induced in male Wistar rats for 2 h using the suture occlusion technique." | 1.32 | Exogenous brain-derived neurotrophic factor prevents postischemic downregulation of [3H]muscimol binding to GABA(A) receptors in the cortical penumbra. ( Kiessling, M; Kollmar, R; Schäbitz, WR; Schwab, S; Sommer, C, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sommer, C | 2 |
| Kollmar, R | 1 |
| Schwab, S | 2 |
| Kiessling, M | 1 |
| Schäbitz, WR | 2 |
| Zhang, F | 1 |
| Li, C | 1 |
| Wang, R | 1 |
| Han, D | 1 |
| Zhang, QG | 1 |
| Zhou, C | 1 |
| Yu, HM | 1 |
| Zhang, GY | 1 |
| Müller, HD | 1 |
| Hanumanthiah, KM | 1 |
| Diederich, K | 1 |
| Lyden, PD | 1 |
| Lonzo, L | 1 |
| Kanie, S | 1 |
| Yokoyama, O | 1 |
| Komatsu, K | 1 |
| Kodama, K | 1 |
| Yotsuyanagi, S | 1 |
| Niikura, S | 1 |
| Nagasaka, Y | 1 |
| Miyamoto, KI | 1 |
| Namiki, M | 1 |
5 other studies available for muscimol and Cerebral Infarction
| Article | Year |
|---|---|
Exogenous brain-derived neurotrophic factor prevents postischemic downregulation of [3H]muscimol binding to GABA(A) receptors in the cortical penumbra.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain Ische | 2003 |
Activation of GABA receptors attenuates neuronal apoptosis through inhibiting the tyrosine phosphorylation of NR2A by Src after cerebral ischemia and reperfusion.
Topics: Analysis of Variance; Animals; Apoptosis; Baclofen; Brain Ischemia; Cerebral Infarction; Disease Mod | 2007 |
Brain-derived neurotrophic factor but not forced arm use improves long-term outcome after photothrombotic stroke and transiently upregulates binding densities of excitatory glutamate receptors in the rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Brain-Der | 2008 |
Combination therapy protects ischemic brain in rats. A glutamate antagonist plus a gamma-aminobutyric acid agonist.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Dizocilpine Maleate; Drug Combinations; Excitat | 1994 |
GABAergic contribution to rat bladder hyperactivity after middle cerebral artery occlusion.
Topics: Animals; Baclofen; Bicuculline; Cerebral Infarction; Cerebral Ventricles; Dose-Response Relationship | 2000 |