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muscimol and Cerebral Hemorrhage

muscimol has been researched along with Cerebral Hemorrhage in 3 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"We conclude that muscimol significantly improves neurological outcome after intracerebral hematoma."7.69Medical therapy for intracerebral hematoma with the gamma-aminobutyric acid-A agonist muscimol. ( Jackson-Friedman, C; Lonzo-Doktor, L; Lyden, PD, 1997)
"Baclofen (20 mg/kg) was neuroprotective (potency ratio of 3."5.30High dose baclofen is neuroprotective but also causes intracerebral hemorrhage: a quantal bioassay study using the intraluminal suture occlusion method. ( Jackson-Friedman, C; Jin, A; Lyden, PD; Nunez, S; Zweifler, R, 1997)
"We conclude that muscimol significantly improves neurological outcome after intracerebral hematoma."3.69Medical therapy for intracerebral hematoma with the gamma-aminobutyric acid-A agonist muscimol. ( Jackson-Friedman, C; Lonzo-Doktor, L; Lyden, PD, 1997)
"Baclofen (20 mg/kg) was neuroprotective (potency ratio of 3."1.30High dose baclofen is neuroprotective but also causes intracerebral hemorrhage: a quantal bioassay study using the intraluminal suture occlusion method. ( Jackson-Friedman, C; Jin, A; Lyden, PD; Nunez, S; Zweifler, R, 1997)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishida, A1
Isa, K1
Umeda, T1
Kobayashi, K2
Hida, H1
Isa, T1
Lyden, PD2
Jackson-Friedman, C2
Lonzo-Doktor, L1
Nunez, S1
Jin, A1
Zweifler, R1

Other Studies

3 other studies available for muscimol and Cerebral Hemorrhage

ArticleYear
Causal Link between the Cortico-Rubral Pathway and Functional Recovery through Forced Impaired Limb Use in Rats with Stroke.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Jan-13, Volume: 36, Issue:2

    Topics: Animals; Biotin; Cerebral Hemorrhage; Deep Brain Stimulation; Dextrans; Disease Models, Animal; Doxy

2016
Medical therapy for intracerebral hematoma with the gamma-aminobutyric acid-A agonist muscimol.
    Stroke, 1997, Volume: 28, Issue:2

    Topics: Animals; Caudate Nucleus; Cerebral Hemorrhage; Collagenases; Drug Evaluation, Preclinical; GABA Anta

1997
High dose baclofen is neuroprotective but also causes intracerebral hemorrhage: a quantal bioassay study using the intraluminal suture occlusion method.
    Experimental neurology, 1997, Volume: 147, Issue:2

    Topics: Animals; Baclofen; Biological Assay; Cerebral Hemorrhage; Cold Temperature; Dizocilpine Maleate; Exc

1997