muscimol has been researched along with Cerebellar Ataxia in 5 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study indicates that the hypermetria of ipsiversive saccades after inactivation of the monkey FOR is primarily due to a uniform gain increase for all sizes of saccades." | 1.31 | Saccadic dysmetria following inactivation of the primate fastigial oculomotor region. ( Iwamoto, Y; Yoshida, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dar, MS | 1 |
| Buzunov, E | 1 |
| Mueller, A | 1 |
| Straube, A | 1 |
| Robinson, FR | 1 |
| Quinet, J | 1 |
| Goffart, L | 1 |
| Tiemeyer, MJ | 1 |
| Singer, HS | 1 |
| Troncoso, JC | 1 |
| Cork, LC | 1 |
| Coyle, JT | 1 |
| Price, DL | 1 |
| Iwamoto, Y | 1 |
| Yoshida, K | 1 |
5 other studies available for muscimol and Cerebellar Ataxia
| Article | Year |
|---|---|
Functional interaction and cross-tolerance between ethanol and Δ9-THC: possible modulation by mouse cerebellar adenosinergic A1/GABAergic-A receptors.
Topics: Adenosine; Animals; Cannabinoid Receptor Agonists; Central Nervous System Depressants; Cerebellar At | 2014 |
When during horizontal saccades in monkey does cerebellar output affect movement?
Topics: Animals; Cerebellar Ataxia; Cerebellar Nuclei; Functional Laterality; GABA-A Receptor Agonists; Maca | 2013 |
Saccade dysmetria in head-unrestrained gaze shifts after muscimol inactivation of the caudal fastigial nucleus in the monkey.
Topics: Animals; Cerebellar Ataxia; Cerebellar Nuclei; Head Movements; Macaca mulatta; Muscimol; Photic Stim | 2005 |
Synaptic neurochemical alterations associated with neuronal degeneration in an inherited cerebellar ataxia of Gordon Setters.
Topics: Animals; Cerebellar Ataxia; Dogs; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Muscimol; Synaps | 1984 |
Saccadic dysmetria following inactivation of the primate fastigial oculomotor region.
Topics: Animals; Cerebellar Ataxia; Cerebellar Nuclei; GABA Agonists; Macaca mulatta; Male; Muscimol; Saccad | 2002 |